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Biomedical subjects

B Monk

Publications and source records attributed to B Monk.

At least 19 recordsLinked to original sources
PubMed1989

Induction of hair growth in alopecia totalis with diphencyprone sensitization.

The therapeutic use of the induction of an allergic contact sensitivity to diphencyprone in alopecia areata has been studied. Fourteen subjects had alopecia totalis and four had extensive and long-standing alopecia areata. Topical diphencyprone was capable of inducing an allergic contact sensitivity in 16 subjects (89%), and 13 of these agreed to proceed to repeated intermittent applications to the left side of the scalp, the right side acting as an untreated control; six subjects achieved cosmetically useful regrowth of normally pigmented terminal hair. No clinical features seemed to distinguish those who showed a favourable response from those who did not.

Adult↗
PubMed1985

Ageing and the skin.

Advances in our understanding of ageing in the skin mean that many of the undesirable stigmata of growing old may be delayed or prevented. This is important not merely for reasons of vanity but also because ageing in the skin is associated with the development of a variety of tumours.

Aging↗
PubMed1980

The 4-methylumbelliferone sulphate sulphatases of human tears.

The properties of human tear 4-methylumbelliferone sulphate sulphatase (EC 3.1.6.1) have been investigated. More than 80% of the enzyme activity behaved as the acidic A isoenzyme on isoelectric focusing and DEAE-cellulose ion exchange chromatography. The distribution of enzyme activity in a normal population has been investigated. The least interindividual variation was seen when enzyme activities were calculated as units per mg tears. The alpha-galactosidase, beta-N-acetylglucosaminidase and sulphatase enzyme activities in human tears varied independently of each other. The use of tear sulphatases for the detection of metachromatic leukodystrophy (McKusick 24980) is discussed.

Acetylglucosaminidase↗