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Biomedical subjects

B Milleron

Publications and source records attributed to B Milleron.

At least 163 records · Page 9Linked to original sources
PubMed1978

[Voluminous tracheal diverticulum. One case (author's transl)].

A tracheal diverticulum, probably of congenital origin, was discovered accidentally during the course of a broncho-pulmonary affection. Diverticuli of the trachea are usually found during a simple systematic radiological examination, or when an established pulmonary condition is being investigated. Routine bronchography, alone, or associated with a tomograph, can be used to demonstrate its characteristics and precise location. Bronchoscopy may then be carried out in order to study the area surrounding the diverticular orifice more closely, and to establish the condition of its mucous lining. Several evolutive stages are involved in the pathogenesis of tracheal diverticuli, varying from a rudimentary bronchiole to megalotrachea, which, for many authors, is an autonomous condition because of its anatomical and pathological make-up, producing its own well-defined symptomatology.

Aged↗
PubMed1978

[Clinical study of pleural fibromas].

After 3 personal observations of pleural fibromas, 67 analogous cases have been recorded. Clinical, radiological and pathological signs are recalled. The authors stress the 2 points which can turn this benign tumour into a serious disease :--onset of major hypoglycemia,--recurrences happening in a malignant fashion.

Adult↗
PubMed1978

[Isolated cystic lymphangioma in the mediastinum].

Cystic lymphangioma localized only in the mediastinum is a rare type of primitive tumour (less than 1% of the mediastinum primitive tumours). These three new observations concern lymphangiomas with an anterior position ; therir anatomical connections with the lymphatic system are difficult to show. Treated by surgery these benign tumours have a good prognosis and only a few cases of local recurrences have been reported.

Adult↗
PubMed1977

[Pseudo-tumoral round atelectasis without known pleural history (apropos of 2 cases)].

The authors recall two cases of round atelectasis without any known pleural past-record. The first showed, on successive X rays, an increase in size of the image. In the second case a pleural effusion occurred after the discovery of a round opacity. They stress the various small radiological signs as a way of including the etiology of a purely mechanical atelectasis among the difficult diagnosis of intraparenchymal round opacities.

Adult↗
PubMedDate not supplied

[Cytological diagnosis of bronchial cancers from samples obtained through broncho-fibroscopy].

The results of cytological studies of samples obtained by fibre endoscopy of the bronchus in 160 cases of bronchial ; carcinoma were analysed. Thanks to the routine use of brushing, aspiration, often selective and sputum examination, the diagnosis was obtained in 62% of cases. Naturally it was mainly positive in the proximal budding forms (78%) but the figures in the distal forms, including those where fibre endoscopy was negative, remained high (54%). There was never a true false positive, and the cytohistological correlation was almost 100%. Distal aspirations were the most useful in peripheral forms, whilst brushing was more useful in proximal forms. In any case thanks to these new technics, fibre endoscopy has become a simple examination for routine use which has now a very important place in the diagnosis of bronchial carcinoma.

Adult↗
PubMedDate not supplied

[Destroyed lung (author's transl)].

The expression of "destroyed lung" is, now, accepted to designate the large destructions of the lung, secondary to pulmonary and essentially infectious diseases, the cure of which is obtained but with important sequelae. The main cause remains tuberculosis, cured by chemotherapy. Some large pulmonary suppurations, treated by antibiotics, can lead to the same sequelae. These "destroyed lungs" can keep an asymptomatic form. But often, about ten years after the initial disease, they cause several troubles such as progressive dyspnea leading to irreversible respiratory insufficiency, repeated pulmonary infectious episodes and hemoptysis, the risk of which is increased by aspergillosis. The radiological aspect of these "destroyed lungs" is made of opacities with multiple cavities or with one unique large cavity. The mechanism of hemoptysis has been understood recently: all destructive lesion of the pulmonary tissue produces as a consequence a development of the systemic blood circulation, bronchial or parietal, with reverse blood circulation from systemo-pulmonary anastomoses-which can produce capillary dilatations-into the pulmonary artery. All these complications can lead to a surgical treatment. Embolization of bronchial arteries is a less aggressive method when hemoptysis is the main symptom. These acquires "destroyed lungs" can be compared to those caused by extensive pseudokystic bronchiectases. For both cases clinical aspects and therapeutic methods are similar, though the lesions are fixed and likely congenital in the last form.

Adult↗
PubMedDate not supplied

[Clinical aspect and actual frequency of bilateral squamous cell bronchial carcinoma with simultaneous revelation (author's transl)].

Clinical and physiopathological data about 10 cases of bilateral squamous cell bronchial carcinoma with simultaneous revelation, are reviewed. This clinical form is not rare, usually found by a systematic bilateral endoscopy. In these 10 cases, the clinical and radiological data did not allow to predict the diagnosis before the endoscopy. Physio-pathological mechanisms are not well established. Various hypotheses are propounded : air-way, blood or lymphatic metastases, simultaneous tumoral blossoming, superficial propagation, genetic factors intervention. For these 10 cases, the authors develop arguments for one or another of these mechanisms.

Aged↗
PubMedDate not supplied

[Carcinoid tumor of the thymus: report of a case (author's transl)].

Carcinoid tumor primarily developing in the thymus gland is very rare. A new case is reported to add to the 35 previously reported. In most cases, patients have no endocrinological syndrome; the tumor is rarely associated with a multiple endocrine adenomatosis. This neoplasm probably derived from Kultschizky cells which are present in the normal thymus gland. Histologically they are very similar to the carcinoid tumor of other organs. Complete surgical excision is the best treatment when possible.

Apudoma↗
PubMedDate not supplied

[Clinical and evolutive characteristics of bronchial cancers discovered by systematic X-ray examinations (author's transl)].

The characteristics of broncho-pulmonary cancers discovered during systematic X-ray were studied over an 11 year period by comparison with cancers discovered through their symptoms. The operability of first group patients was definitely superior (62.5% against 36.7%y and so was the 5 year survival (18.7 against 5.5%). These differences are statistically significant and should be remembered, before the results of extensive anglo-saxon surveys be known, about the value of X-ray detection of bronchial cancer--at least in high risk patients.

Adenocarcinoma↗
PubMedDate not supplied

Immunochemotherapy in 34 cases of oat cell carcinoma of the lung with 19 complete responses.

Thirty-four previously untreated patients with oat cell carcinoma of the lung were treated with a myelotoxic combination of cyclophosphamide, adriamycin, methotrexate, CCNU, and Corynebacterium parvum (regimen A) every 4 weeks, interspersed with a non-myelotoxic combination including bleomycin, vincristine, dehydroemetine, and Corynebacterium parvum (regimen B) weekly the other 3 weeks or when hematologic toxicity prohibited administration of regimen A. Hematologic toxicity was frequent but was never a serious problem except in two cases of profound leukopenia in which fatal supervening infection occurred. Nineteen patients in this series (56%) showed a complete response lasting from 4+ to 65+ months. Eight of these patients are still alive with a followup of 6+ to 65+ months. Nine patients (26%) showed a partial response (greater than 50%) lasting 1-10+ months. Only one patient in this group is surviving (10+ months). The overall response rate was thus 82%. It is concluded from this study that only a complete response has any significant effect on survival, the benefit of a partial response over no response being only slight. The results achieved are compared to those of available series in the literature and from this comparison strategic deductions for the treatment of oat cell carcinoma of the lung are made.

Adult↗