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Biomedical subjects

B Millat

Publications and source records attributed to B Millat.

At least 91 records · Page 5Linked to original sources

[Therapeutic approach to pulmonary embolism].

The purpose of this study is the retrospective evaluation of the treatment of 196 cases of pulmonary embolism. Therapeutic attitude was standardized. Intravenous heparin followed early on by oral anticoagulants remains the basic treatment of the majority of patients (74%). This treatment could be associated with: (1) Fibrinolysis with urokinase bolus at the time of massive pulmonary embolism with clinical and hemodynamic signs of shock (14%). No severe hemorrhagic complication was observed. 2) Inferior vena caval interruption in case of contraindications or failure of anticoagulation (29%). Only one death was observed in this study.

Anticoagulants↗

[Temporary minimal esophagostomy in the surgical treatment of malignant esophago-respiratory fistulas].

Oesophago-bronchial and oesophago-pleural fistulae are serious complications of oesophageal cancers. They occur earlier than is generally believed and, if untreated, result in death caused by septic and respiratory complications. An original two-stage surgical method is reported and illustrated by 3 cases. The first stage consists of excluding the oesophagus at both ends and introducing, through a small oesophagostomy, a Foley's catheter to aspirate the secretions; the cardia is excluded by stapling; jejunostomy is performed by the catheter technique. The second stage consists of oesophageal reconstruction. The functional result is of such quality that the indications for palliative endoscopic intubation, perhaps used too routinely at present, should be revised.

Adult↗

[Infectious complications of diverticular sigmoiditis: can the failure of medical treatment be predicted?].

A retrospective study of case histories of 36 patients with infectious complications of sigmoid diverticulitis (excluding peritonitis) compared clinical, biologic and radiologic signs in a group responding favorably to medical treatment (24 cases) and a group requiring surgery after a mean of 9 days of treatment in a surgical ward (12 cases). Six signs were found to be related to the course of the disease: a painful left iliac mass on admission, persistence or increase in pain after 48 hours, absence of restoration of normal intestinal transit, temperature below 36.5 degrees C or above 37.8 degrees C, leucocytosis of less than 2,500 or more than 13,500/mm3, evidence of radiologic stenosis by simple contrast enema. A prospective study could assess the prognostic value of these signs as determinants of failure to respond to medical treatment.

Acute Disease↗

[Peripheral intravenous infusions. Reduction of morbidity owing to an electronic controller of infusion flow rate].

The ability of an electronic infusion controller (IVAC 230) to reduce morbidity in peripheral intravenous infusions was investigated in a controlled randomized trial. The results were assessed on the number of sites of injection in relation to the total duration of perfusion, with an adjustment for the quality of the fluids infused. Using the controller resulted in a 50% decrease in the number of sites of injection (risk alpha = 1%, beta = 10%).

Electronics, Medical↗

[Use of the gallbladder in the re-establishment of biliary continuity].

Five procedures using the gallbladder to re-establish biliary or biliary-digestive continuity have been described. A new technique, is presented, which was applied in a case of benign, acute cryptogenetic stenosis requiring full resection of the common hepatic duct. Owing to its theoretical advantages, this new technique may be considered when post-operative results are dependent upon the risks inherent in reflux cholangitis, as is the case in liver transplantation.

Adult↗

[Postoperative continuous or cyclic total parenteral nutrition].

In patients with inflammatory bowel disease treated by total parenteral nutrition (TPN), the incidence of TPN-induced cholestasis may be reduced by discontinuous (cyclic) TPN. In order to test this statement, a prospective trial was carried out in which 21 selected adults requiring at least 12 day postoperative nutrition were randomly allocated to two groups: continuous vs cyclic TPN. The efficiency, evaluated on nitrogen balance and prealbumin levels, was no different. Those patients undergoing cyclic-TPN needed more insulin in the first four postoperative days. The incidence of biological cholestasis was the same in the two groups. This prospective study gave strong evidence against the potential benefit of cyclic rather than continuous TPN in postoperative patients. Nonetheless, additional prospective trials using larger patient populations and greater lengths of TPN are needed to confirm these findings.

Adult↗

[Acute pancreatitis: severity factors. Retrospective analysis of 78 cases].

Retrospective analysis of clinical and laboratory findings was undertaken in 78 patients in which pancreatitis was confirmed pathologically. In our experience, severity factors are as follows: age over 55 years and, during the first 48 hours, fall in haematocrit of more than 10%, corrected plasma calcium lower than 8 mg %, plasma creatinine greater than 30 mg/1, hypoxia less than 60 mm Hg, resistant to assisted ventilation, liquid sequestration more than 6 litres. These objective parameters define the group of patients who, in our experience, should derive benefit from new suggested forms of treatment.

Acute Disease↗

[Postoperative cholecystitis. Apropos of 9 cases (3 lithiasic and 6 alithiasic)].

Postoperative cholecystitis (three cases with and six cases without associated stones) was found following 25.00 operations performed over a period of 8 years. Analysis of these cases and a literature review suggest that the onset of a postoperative lithiasic cholecystitis is probably only the result of coincidence, where as alithiasic cholecystitis is a definite postoperative complication, these affections having to be considered within the more general framework of post-aggression cholecystitis.

Acute Disease↗

[Hydatid cyst of the pancreas. One case (author's transl)].

This particular location is rare but should be more frequently detected with the help of ultrasonography, CT and serological tests. The surgical indications, which depend upon the effects of the cyst on pancreatic ducts and vessels, are discussed.

Adult↗