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Biomedical subjects

B Marković

Publications and source records attributed to B Marković.

At least 19 recordsLinked to original sources
PubMed1992

[Cytogenetic changes in persons exposed to polychlorinated biphenyls].

A cytogenetic study performed in a group of workers exposed to polychlorinated biphenyls comprised analysis of structural chromosomal aberrations in the lymphocytes in the first division in vitro, analysis of micronuclei frequency in binuclear lymphoblasts induced by cytochalasin B and analysis of sister chromatid exchanges. The study included 48 exposed workers and 15 controls. In 16 exposed workers increased incidence of unstable chromosomal aberrations (dicentrics, rings and acentrics) was found, while in 19 no structural chromosomal aberrations could be detected. In 11 workers changes defined as chromosomal and chromatid breaks were noted. This type of change, however, can be evidenced in a non-exposed population as well. In two workers stable chromosomal aberrations were recorded (translocations and inversions). The incidence of micronuclei as well as exchange of sister chromatids were elevated in the exposed group of workers compared to controls.

Adult↗
PubMed1990

[Balkan nephropathy. Current problems of pathogenesis and carcinogenesis].

An important characteristic in the pathogenesis of Balkan nephropathy is the long latent period between the start of exposure and the clinical manifestation of the disease. The pathogenic mechanisms involved in this process are considered in both the adult and the child. Certain essential questions relating to carcinogenesis are also considered, urothelial cancer being very often associated with Balkan nephropathy.

Adolescent↗
PubMed1989

[Tumors of the retroperitoneum].

Authors present 13 patients with tumors of the retroperitoneal space. Primary tumors were revealed in 84.6%, malignant tumors in 92%, mesodermal source in 100%, liposarcomas in 30%, Operative treatment was undertaken in all patients, radical operation in 5 patients, radical operation with intervention on the surrounding structures in 4 patients, reduction tumor in one and biopsy in 3 patients.

Adult↗
PubMed1988

Erythrocyte and plasma glutathione levels in patients with chronic renal insufficiency.

Reduced glutathione (GSH) levels were investigated in the erythrocytes and plasma of nondialyzed patients with varying degrees of renal insufficiency and also of patients on regular hemodialysis treatment. GSH levels were from 19 to 70% higher in the erythrocytes of examined patients as compared to their corresponding age-matched controls. A correlation was found between the degree of renal insufficiency and the erythrocyte GSH level. No variations in plasma GSH levels which could be related to the degree of renal deterioration were observed. A routine hemodialysis did not significantly affect erythrocyte and plasma GSH levels. No significant differences in GSH levels between anemic and nonanemic uremic patients were observed.

Anemia↗
PubMed1988

Acid and alkaline phosphatase activity in bone-cyst fluid.

The acid and alkaline phosphatase activity in fluid aspirated from solitary bone cysts in six patients was measured, and large increases in the concentration of acid phosphatase were found. In some cases this increase was reflected in venous blood concentrations. The significance of these findings for the pathogenesis and the management of solitary bone cyst is discussed.

Acid Phosphatase↗
PubMed1985

[Balkan nephropathy and transitional cell carcinoma. Pathogenetic problems and the early phase of cancerogenesis].

Balkan Nephropathy belongs to the group of primary chronic interstitial nephropathy with tubular functional abnormalities at early clinical stage. This disease may occur at any age and may affect all members of the same family including the children existing in them in latent form. The coincidental occurrence of Balkan Nephropathy and urothelial carcinoma has been very often observed. The actual problems of early Balkan Nephropathy pathogenesis and carcinogenesis are considered.

Adult↗
PubMed1985

[Malignant mesenchymoma in the region of Denonvillier's fascia].

A case with malignant mesenchymoma in the region of Denonvillier's fascia is presented. This localization has not been described in the literature up to now. It presented clinically by acute urinary retention. Morphologically it consists of three components: leiomyosarcoma, liposarcoma and chondrosarcoma. Tumor ablation with adenomectomy was performed by a retropubic approach.

Aged↗
PubMed1983

[Juxta-vesical ureterolithotomy with intubation of the distal part of the ureter without opening the urinary bladder].

A new surgical method in the treatment of juxtavesical ureterolithiasis is described; its advantage in relation to the classical juxtavesical ureterolithotomy is in the intubation of distal part of the ureter without incision of the bladder. In this way a stenosis at the place of ureterolithotomy is prevented, and on the other side the existent stenosis is dilated. 23 patients have been operated upon, in 9 of whom there was a blockage of the kidney caused by a stone in juxtavesical part of the ureter, with uretero-hydronephrosis in 14 patients. In 14 patients the urine was infected, and in 9 ones sterile; the stone has been in the ureter about 2-3 months in 15 cases. In all patients an extraction of the stone by a Dormy catheter has been tried, but without success. The follow-up of the patients, 8-12 months after surgery showed that the kidney does secrete well, ureter was with a fair passage at the x-ray, and without stenosis of the ureter.

Adult↗
PubMed1982

[Specifics of atelectasis after lumbotomy].

The results three years observation of postoperative lung atelectasis have shown that it is not so frequent, by urological patients in the decubito lateral position. The five cases were all on the left lung, as explained in the previous text. Their maximal incidence begins 24 hours after the operation. If it is suspected on atelectasis, there is no problem in diagnosing it, and for the treatment of it you only need bronchial catheter 6-8 CH. and a lung X-ray. Don't give up with the first try of disobstruction of the bronch or leave the patient and wait. Conservative treatment leads to all the complications mentioned in the former text, if the airing of atelectasis area is not carried out in time. The temperature always promptly falls if the reexpansion of lungs is achieved. We must very certainly differ a pneumonia from atelectasis, because a failure may be disastrous. This process is reversible, if the treatment is begun in time. All this shows that a clinical doctor must seriously observate the patient's postoperative course and every sign and symptom.

Humans↗