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Biomedical subjects

B Maguire

Publications and source records attributed to B Maguire.

36 records · Page 2Linked to original sources

Attitudes about AIDS.

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Acquired Immunodeficiency Syndrome↗

Recent graduates' evaluation of their dental school education.

To assess recent dental graduates' perceptions about the adequacy of their education, a random sample of individuals who graduated between 1980 and 1982 was surveyed. The 362 respondents (56 percent response rate) indicated their perceived level of preparedness and the importance to practice of 75 topics in the dental school curriculum. The means for level of preparedness and importance to practice were plotted for each of the 75 topics. Those topics that new dentists believed to be underemphasized or overemphasized in the curriculum were identified. These findings have implications for planning curricular changes for dental education.

Adult↗

Experiment on aggregation of red cells under microgravity on STS 51-C.

Kinetics and morphology of aggregation of red cells were studied using automatic slit-capillary photo-viscometers, one situated on the middeck of the space shuttle 'Discovery', and the other in the ground laboratory at KSC. Experiments were run simultaneously, blood samples being adjusted to haematocrit of 0.30 using native plasma, at temp. of 25 degrees C, and anticoagulated by EDTA. Donors included patients with myocardial infarction, insulin-dependent diabetes, hyperlipidaemia and hypertension. Macro and microphotographs were obtained during flow and stasis. There was a striking difference in the morphology of aggregates formed in space and on the ground. Aggregates formed under zero gravity showed rouleaux formation, while the same blood samples showed severe clumping on the ground, in all patients blood. Normal blood showed rouleaux on the ground, but a random swarm-like pattern in space. The shape of the red cells remained normal under zero gravity.

Colonic Neoplasms↗

Extent of urinary excretion of p-hydroxyphenytoin in healthy subjects given phenytoin.

Urinary excretion of p-hydroxyphenytoin and its glucuronide conjugate was measured in eight healthy young adults in a comparative bioavailability study of oral sodium phenytoin (approximately 5 mg/kg/dose). Among these subjects the percentage of the phenytoin dose converted to p-hydroxyphenytoin and appearing in urine was relatively similar (mean 79%, range 67-88%). The great majority of the p-hydroxyphenytoin appeared in urine as conjugates; only 1.4-3.4% of the excreted p-hydroxyphenytoin was in the form of unconjugated metabolite. The proportion of a single phenytoin dose excreted in urine as p-hydroxyphenytoin or its conjugate increased from the first dose (mean +/- SD) 74.9 +/- 4.6% to the second dose, given 2 weeks later 79.3 +/- 4.6% (p less than 0.05). This finding suggests that autoinduction of phenytoin metabolism may occur after relatively brief exposure to the drug.

Adult↗

Measurement of Aggregation of Red Cells in space--a project for the NASA space shuttle.

Progress is described on the advanced stages in design of an instrument for the study of red blood cell aggregation and blood viscosity under near-zero gravity conditions. This paper gives a brief review of the experiment and its background and a description of the design of the instrument intended for space conditions. Summaries are given of solutions to some problems peculiar to a space experiment, particularly blood storage, microscope focusing, experiment control and data acquisition.

Blood Sedimentation↗

Laparoscopy.

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Endoscopy↗

Do the benefits of continuing education outweigh the costs?

Debate on the costs and benefits of continuing professional education for nurses has intensified following the PREPP proposals. Evidence suggests that nurses who consider that their educational needs are being fully met have higher morale and work more efficiently than those who do not.

Cost-Benefit Analysis↗

The professional role of the nurse.

The extent to which nurses feel that their contribution is recognized and that they are involved in important decisions varies according to grade and location. Clinical nurses generally feel that they exert little influence over doctors, general management or their own nurse managers.

Decision Making↗

Factors influencing job satisfaction among nurses.

This article considers the results of an opinion survey of nurses working in Gwynedd, North Wales. Present changes to the structure and function of the NHS are heightening concerns and eroding the strengths of the profession. Action is needed if nursing's move towards enhanced professional status is to be maintained.

Career Choice↗

Public acceptance of the Surgeon General's brochure on AIDS.

Public acceptance of the Surgeon General's brochure, "Understanding AIDS," was investigated in a nationwide telephone survey of a representative sample of 2,000 adults generated by random digit dialing. A response rate of 75 percent was achieved. A total of 59 percent of respondents remembered receiving the brochure; of these, 68 percent read most of it and 20 percent read half of it or less. Most respondents reacted positively; 86 percent believed that it was a good use of government money, and only 7 percent would have preferred not getting it. Analysis by demographic characteristics indicated that blacks and young people were less likely to remember receiving the brochure than were whites and retired persons. The public health community can assume that the mailing met with resounding approval and that other public health brochures would be welcomed.

Acquired Immunodeficiency Syndrome↗