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Biomedical subjects

B M Tolia

Publications and source records attributed to B M Tolia.

30 records · Page 2Linked to original sources

Xanthogranulomatous pyelonephritis: segmental or generalized disease.

Xanthogranul omatous pyelonephritis of the kidney usually occurs in association with urinary tract infection, obstruction and/or calculi. The diagnosis usually is made when a nephrectomy is performed for a non-functioning kidney and/or a mass indistinguishable from carcinoma on radiological as well as gross examination. Segmental excision of the kidney for focal xanthogranulomatous pyelonephritis has been used rarely in the past. Focal involvement of the kidney with xanthogranulomatous pyelonephritis was encountered in 4 instances at our institution. The diagnosis was made incidentally in 3 patients during segmental excision of the involved parenchyma and/or cyst wall. We believe that the xanthogranulomatous process probably starts as a localized involvement in some cases and, if excised during this stage, further destruction of renal parenchyma can be prevented successfully.

Adult↗

Carcinoma of prostate presenting as retroperitoneal mass.

The pattern of dissemination of prostatic carcinoma varies, but skeletal metastasis is the single most common symptomatic mode of presentation. The clinical course and treatment of the 2 cases presenting with symptomatic metastases to the retroperitoneum are described in detail and pertinent literature is reviewed.

Adenocarcinoma↗

Symptomatic renal angiomyolipoma: report of 8 cases, 2 with spontaneous rupture.

Of the 97 patients with symptomatic renal angiomyolipoma not associated with tuberous sclerosis reported in the literature 13 have presented with a clinical picture of shock because of spontaneous rupture and massive retroperitoneal hemorrhage. Eight new patients with symptomatic renal angiomyolipomas are described, 2 of whom presented with an acute abdomen. Renal angiomyolipomas are essentially benign tumors. Several angiographic and pyelographic characteristics have been described but none appears to be unequivocally diagnostic. Because of the inability to make a precise preoperative diagnosis and the possibility of massive hemorrhage, nephrectomy is indicated in patients with such unilateral solid tumors in the absence of the tuberous sclerosis complex.

Adult↗

Testicular torsion in adults: plea for its consideration early in clinical evaluation of acute scrotum.

A case of a thirty-eight-year-old man with acute scrotum is presented. Past history of transient episodes of testicular pain, negative findings on urinalysis, and lack of symptomatic relief despite antibiotic therapy plus a high index of suspicion helped establish the correct diagnosis of testicular torsion. A long delay between onset of symptoms and surgical exploration resulted in testicular infarction. A plea is made to consider torsion of the testis even in the adult with scrotal pain when all of the classic clinical criteria of epididymitis are not present.

Acute Disease↗

Bowen's disease of shaft of penis. Successful treatment with 5-fluorouracil.

Bowen's disease is a precancerous lesion of the superficial layers of the skin. The topical application of 5-fluorouracil has been successfully used in the treatment of such lesions. An ususual case of Bowen's disease of the skin of the penile shaft treated successfully with topical 5-fluorouracil is presented along with a review of different modes of treatment.

Administration, Topical↗