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Biomedical subjects

B M Slotnick

Publications and source records attributed to B M Slotnick.

67 records · Page 4Linked to original sources
PubMed1966

Deficits in passive avoidance and fear conditioning in mice with septal lesions.

By means of a simple activity measure, mice with lesions of the septal forebrain were tested for passive avoidance (response inhibition) and fear conditioning. In two separate experiments animals with septal lesions showed little or no conditioning, as evidenced by lack of suppression of activity during and following activitycontingent foot shock. Results support and extend thehypothesis that these deficits in passive avoidance derive from the removal of normal inhibitory influences mediated by the septal area.

Animals↗
PubMedDate not supplied

Variability in the stereotaxic position of cerebral points in the albino rat.

An analysis of variability in the stereotaxic position of five cerebral points in rats revealed: (1) that variability was less from the bregma skull point than from ear-bar-zero or the lambda skull point, (2) that high correlations exist between the position of skull points and cerebral structures, and (3) that the use of two external landmarks for predicting the position of cerebral targets produces a greater than 40% reduction in errors over that resulting from the use of single (ear-bar-zero or skull landmark) predictors.

Aging↗
PubMedDate not supplied

Transection of the lateral olfactory tract does not produce anosmia.

Rats trained in an olfactometer were tested for retention of an odor detection and odor discrimination task after lesions of the olfactory peduncle. Large lesions of the peduncle, including transection of the lateral olfactory tract and anterior commissure resulted in severe deficits in retention and relearning but did not produce anosmia. Discrete lesions of the lateral olfactory tract had little or no effect on retention. The results indicate that the lateral and intermediate olfactory pathways are not essential for smell and suggest that significant olfactory function may be mediated by medial olfactory bulb projections.

Animals↗