The function of the thyroid gland transplanted after being frozen to --196 degrees C was studied in experiments on rats. The gland was transplanted to thyroidectomized animals. Glands frozen without the use of cryoprotective agents and also in the presence of a cryoprotector--polyethyleneoxide with a mol. wt. of 400 (PEO-400) were used. Besides, a study was made of the effect of different rates of chilling on the thyroid gland. In assessment of the gland function a determination was made of tissue respiration, of I-131 consumption, and blood thyroid hormone content. To assess the cryoprotective effect of PEO-400 and for the choice of its optimal concentration the NMR method and roentgenostructural analysis werea applied. The thyroid gland proved to take and to retain its capacity to hormone formation after its freezing to the temperature of --196 degrees C according to a special program in the presence of PEO-400.

Animals↗

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[Patogenetic bases of the preparation choice in treatment of purulent wounds].

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Anti-Bacterial Agents↗

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[Choice of methods in determining water space volumes in surgical patients].

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Blood Volume↗

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[Protegentin--a combined preparation for the local treatment of suppurative infection].

Protegentin is a formulation in the form of an ointment for local application. Its high efficacy was demonstrated in the treatment of wounds in the 1st phase of the process, extended decubitus, trophic ulcers, wounds of various genesis not healing for prolonged periods, urogenital infections, abscesses, maxillofacial phlegmon and abscessing parodontosis. The ointment showed good draining, proteolytic and bactericidal effects. The tolerance was good. The positive results were observed in 97 per cent of the cases.

Administration, Topical↗

PubMedDate not supplied

[The morphofunctional characteristics of the normal duodenojejunal flexure and in pathology of the extrahepatic bile ducts].

Results of complex experimental and clinical (146 patients) investigations of the morphofunctional state of the duodeno-intestinal flexure (DIF) are presented. It was established that patients with the pathology of extrahepatic bile ducts had limited mobility of DIF which was responsible for higher intraduodenal pressure and appearance of duodeno-gastric reflux. Mobilization of DIF improves the evacuation of the intestinal contents from the duodenum in patients with the pathology of extrahepatic bile ducts and is thought to be a prophylactic measure against the development of chronic duodenal obstruction after cholecystectomy.

Bile Duct Diseases↗