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Biomedical subjects

B M Coursey

Publications and source records attributed to B M Coursey.

21 records · Page 2Linked to original sources

The standardization of samarium-153.

Samarium-153 has been standardized by 4 pi beta liquid-scintillation counting, with an uncertainty of 0.4%. The probability per decay for the 103.2-keV gamma ray was measured, using two germanium detectors, to be 0.298 +/- 0.004. The half life, based on liquid-scintillation measurements over 6.4 half lives and pressurized-ionization-chamber measurements over four half lives, was found to be 46.27 +/- 0.02 h. The uncertainties given are one estimated standard deviation (of the mean when applicable) for random and non-random components.

Gamma Rays↗

Experimental validation of radiopharmaceutical absorbed dose to mineralized bone tissue.

Therapeutic and palliative uses of bone-seeking radiopharmaceuticals are undergoing clinical trials for human subjects. Radiation dosimetry for these applications is based on the Medical Internal Radiation Dosimetry (MIRD) schema. An experimental method for dosimetry of bone tissue based on electron paramagnetic resonance (EPR) spectrometry is described. Preliminary results for beagle bone exposed to radiopharmaceuticals under clinical conditions have indicated that the EPR dose measurements give approximately the calculated dose, but suggest that the dose distribution may be non-uniform.

Animals↗

Standards of radium-226: from Marie Curie to the International Committee for Radionuclide Metrology.

In the early part of the 20th century, the pioneers of radioactivity research, led by Marie Curie, Ernest Rutherford and Stefan Meyer, formed a Commission internationale des étalons de radium. The Commission made arrangements for the preparation and intercomparisons of the international standards of radium, which were identified as the Paris standard and the Vienna standard. Otto Hönigschmid from Vienna prepared a first set of international secondary standards in 1912 and a second set in 1934. In both instances, these secondary standards were compared by gamma-ray measurements with the Paris and Vienna standards. The usage of these international standards of radium in the 20th century is described.

Journal Article↗