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Biomedical subjects

B Lorcerie

Publications and source records attributed to B Lorcerie.

At least 37 records · Page 2Linked to original sources
PubMed1997

Retroperitoneal fibrosis and infection of an aortic graft prosthesis: diagnosis and therapeutic problems.

The occurrence of a retroperitoneal fibrosis (RPF) after an aorto-bifemoral bypass is unusual. A case of RPF as a complication of an infection of the graft prosthesis is reported. Computed tomography and magnetic resonance imaging prove useful in diagnosing graft infection: they may reveal periprosthetic gas or perigraft fluid persisting for several months after surgery. However, they may fail when they are performed too early, and repeat performance is suggested.

Aged↗
PubMed1995

[Perforation of colonic diverticulum under corticoids: a complication to be known and recognized].

Glucocorticoids can produce acute perforation of colonic diverticula and peritoneal infection. We report two observations in which patients presented a peritoneal collection with no specific clinical signs. The diagnosis was considered after C-T scan or ultrasans. Residues of contrast liquid, after an earlier X-ray exploration, have made the diagnosis of diverticula easier. In one case, corticosteroids were started as a short cure for the treatment of a myeloma. In the other case, patient received a long term corticosteroid therapy at low dose for an asthmatic disease. The perforation was induced by an increased dosage. Diverticular perforations result from inhibition of synthesis of prostaglandins who have the beneficial property of "cytoprotection" and from the immunosuppressive action of glucocorticoids which favour the diffusion of the peritoneal infection. diffusion of the peritoneal infection.

Aged↗
PubMed1994

[Association of infectious aneurysm and microbial spondylodiscitis: physiopathological hypotheses, diagnostic and therapeutic approach].

Two years after a Staphylococcus aureus septicaemia, in a patient with dermatopolymyositis occurred an infectious aneurysm of abdominal aorta with contiguous pyogenic spondylodiscitis. Coexistence of both pathologies is rare and physiopathological mechanisms still remain uncertain. However, many arguments in the present case report are in favour of the initial responsibility of an infectious aneurysm. Main interest in early diagnosing infectious aneurysm, allowed by new investigations such as magnetic resonance imaging and marked leukocyte bone scanning, is the prevention of major complications. Antibiotherapy and surgical removal of infectious aneurysm must be quickly achieved in every case.

Aneurysm, Infected↗
PubMed1993

[Dilated cardiomyopathy disclosing dermatopolymyositis. Management].

Cardiac involvement in dermatopolymyositis is common but rarely symptomatic. Cardiac failure as the presentation is very rare. No correlation exists between the severity of muscular involvement and cardiac involvement. Myocarditis is not uncommon and must be borne in mind if CK MB are above 3% of total CK. It is always associated with electrocardiographic abnormalities. Corticosteroids remain first line treatment. They generally lead to regression of cardiac problems which are usually of secondary importance. If cardiac involvement is severe, the spectacular action of venoglobulins should lead to their use being envisaged from the outset, combined with corticosteroids.

Cardiomyopathy, Dilated↗
PubMed1992

[Intra-alveolar hemorrhages in systemic diseases].

Alveolar haemorrhage is usually, but often belatedly, diagnosed in patients presenting with haemoptysis and radiological alveolar syndrome. Its occurrence frequently marks a turn for the worst in the course of a systemic disease, since its prognosis is sombre. Recognizing its early signs might enable treatment to be instituted and prognosis to be improved. In the presence of typical alveolar haemorrhage, if high-dose corticosteroid therapy and immunosuppressants do not improve the symptoms within 48 hours plasmapheresis must be started. Alveolar haemorrhage must be considered a vital emergency justifying this therapeutic approach without waiting for the hypothetical diagnosis of the underlying systemic disease.

Adolescent↗
PubMed1992

Vascular manifestations in homocystinuria.

Homocystinuria was discovered in a 21-year-old woman when she presented with lower limb ischemia and pulmonary embolism. This patient had a partial deficit in cystathionine-synthetase and took strongly dosed oral contraceptive medication. This report underscores: (1) the value of searching for this type of pathology even in the adult; (2) the possibility of disclosure by another condition, and particularly, drug-induced; (3) the importance of searching for other involved members of the same family; and (4) the possibility of treatment in vitamin sensitive patients.

Adult↗
PubMed1990

[Ischemic vascular complications following thrombopenia induced by heparin. Diagnostic and therapeutic problems].

The authors report 21 cases of heparin-induced thrombocytopenia with ischemic vascular complications. The clinical presentations were peripheral arterial ischemia (16 cases), hemiplegia (1 case) and deep vein thrombosis (4 cases). The vascular surgeon confronted by these complications in an emergency situation should recognise the difficulties of clinical diagnosis (atypical forms) and biological investigations (problems of tests of platelet aggregation). Arterial occlusions are usually accessible to disobliteration with a Fogarty catheter without peroperative heparinisation. Delayed diagnosis explains the seriousness of these complications; in our series of 21 patients, there were 2 deaths, 1 paraplegia, 4 amputations due to arterial problems, 4 severe post-deep vein thrombosis conditions, two of which followed trans-metatarsal amputation. The diagnosis of heparin-induced thrombocytopenia implies immediate withdrawal of heparin therapy. A relay with a low molecular weight heparin is not without risk and should only be undertaken after a negative platelet aggregation test (with the low molecular weight heparin). These tests are rarely practicable in emergency situations and a relay using oral anti-vitamin K antagonists with a rapid onset of action is probably the safest option.

Adult↗
PubMed1989

A comparison of two diet history questionnaires that measure usual food intake.

This study was conducted during the preparation of a case-control study on patients with adenomatous polyps or cancer of the large bowel. It was done to compare two dietary history methods for assessing individual current dietary intakes. Subjects were interviewed concerning their food consumption by meal in one of the questionnaires and by broad food groups in the other questionnaire. Two groups of 20 volunteers, comparable according to sex and age, were interviewed by a dietitian who used one of the questionnaires. Data on diets obtained with the questionnaire were compared with those of a 14-day dietary record. The subjects were informed of the importance of the validation procedure. Whatever the type of questionnaire, mean daily intakes of nutrients and foods were rather similar for the questionnaires and for the 14-day records. Thus, there were more significant correlations between the questionnaire by meal and the record than between the questionnaire by food group and the record. When using tertiles, it appears that the questionnaire by meal was better at classifying individuals with regard to their food intake than the questionnaire by food groups. Although extrapolating these results to a patient population is not straightforward, it seemed likely that interviewing patients on diet without using a pattern of meals would prove even less reliable than for healthy subjects. The questionnaire by meal was preferred to the questionnaire by food groups for the ongoing case-control study. Further studies are needed to know whether these results could be extrapolated to studies on past diet and to non-Latin populations.

Adult↗