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Biomedical subjects

B Lindqvist

Publications and source records attributed to B Lindqvist.

At least 55 records · Page 3Linked to original sources

Extraction of third molars in cases of anticipated crowding in the lower jaw.

The purpose of this study was to ascertain whether the lower third molar, in combination with other variables such as facial morphology and space conditions, can contribute to the occurrence or aggravation of crowding. The subjects consisted of twenty-three boys and twenty-nine girls with impacted third molars on both sides of the mandible. The impacted molar on one side was removed, while the other, nonextracted side was used as a control. Average age at the time of operation was 15.5 years (range, 13 to 19). Close to the operation and annually for at least 3 years afterward, study casts and cephalograms (lateral, frontal, and oblique) were taken. The findings indicated that (1) despite analyses of many variables, this study has not been able to predict which patients should react favorably or unfavorably to removal of the third lower molars in cases of anticipated crowding; (2) in cases with severe crowding removal of the molars could be recommended; (3) correct proximal contacts seem to be of importance in keeping the space that is achieved by extraction, while incorrect ones may spoil it.

Adolescent↗

Fatal reaction following renal angiography and biopsy in diabetic patients with Azotemia.

Severe reactions to contrast media in two diabetic patients with azotemia are described. Both patients also showed signs of immunopathy. The reaction was fatal in one of them. Little is known about contrast media reactions and their natural history. Patients with diabetes mellitus and impaired renal function should be studied with caution and with careful consideration of the indication for the procedure. If an examination with contrast media is considered unavoidable, all diabetic patients with renal failure should be supervised closely to detect the development of acute renal failure. Dehydration should be avoided. Careful monitoring of blood glucose, serum electrolytes, serum creatinine and blood pressure will aid in the early detection of the adverse reaction.

Acute Kidney Injury↗

The protein tolerance of very low birth weight infants fed human milk protein enriched mother's milk.

Pooled breast milk was ultra-filtrated and freeze-dried to give a product with a protein content of 60 g/100 g powder. More than half of the secretory IgA activity against E. coli O antigen was preserved. This concentrated protein was added to the mother's fresh milk providing a protein supply of 3.0-3.5 g/kg/24 hours in four VLBW infants, at a calorie supply of 110 kcal/kg/24 hours. Growth followed the intrauterine rate. Free amino acid levels, acid-base balance and urea concentrations of peripheral whole blood indicated tolerance of the increased supply of human milk protein.

Amino Acids↗

Prognosis curves for patients with polycystic kidney disease.

In patients with polycystic kidney disease and in many patients with other chronic renal diseases kidney function decreases from year to year. When the increase in serum creatinine concentration is followed graphically, the time for dialysis/transplantation can be predicted long beforehand. Based on the course of azotaemia in 34 patients with polycystic disease prognosis curves have been prepared. By comparing the course of a patient with the average course of similar patients, additional information can be gained. A statistical method for making a prognosis curve for kidney function in end-stage polycystic renal disease is described.

Adult↗

Orthodontic care in the Swedish Public Dental Service, county of Västerbotten.

The extent of orthodontic care provided by the children's dentist in collaboration with the specialist in the Public Dental Service in Sweden has been surveyed in a northern county (55,000 sq km, 230,000 inhabitants and a university town with 80,000 inhibitants). All (925) children born in 1962, resident in a coastal, an inland or a mountain municipality, had received regular dental care. Orthodontic treatment up to and including 1976 has been noted from their dental service records. About 35 per cent of the children in the coastal and inland areas had needed and received some form of orthodontic treatment. In the mountain area only 2/3 of the children who needed treatment had received it; this was due to shortage of specialists. The continuing needs of 102 of the patients have been registered at a follow-up examination. The treatment need of the children was used as a measure of the success rate and the need was on average low. The ability of the general practitioner to determine the right time for treatment appears good, as does the capacity for giving treatment in collaboration with the specialist. Further orthodontic training for the general practitioner is recommended in order to maintain a high level of orthodontic ability. Orthodontic facilities in the mountain area ought to be strengthened.

Adolescent↗

Structural studies of the capsular polysaccharide from Streptococcus pneumoniae type 1.

The capsular polysaccharide from Streptococcus pneumoniae type 1 is composed of D-galactopyranosyluronic acid residues and 2-acetamido-4-amino-2,4,6-trideoxy-D-galactopyranosyl residues. The latter sugar, previously unknown in Nature, was not isolated but was identified from the products obtained on deamination of the polymer. Using n.m.r. spectroscopy, methylation analysis, and Smith degradation as the principal methods of structural investigation, it is concluded that the polysaccharide is composed of trisaccharide repeating-units having the structure: leads to 3)-alpha-Sugp-(1 leads to 4)-alpha-D-GalpA-(1 leads to 3)-alpha-D-GalpA-(1 leads to, in which Sug denotes the new sugar.

Carbohydrate Sequence↗

Hyperaminoaciduria in mild phosphate diabetes in adults.

Quantitative urinary amino acid excretion has been studied in 23 adult patients with mild phosphate diabetes (MPD), in 22 adult control patients with various renal disorders and in 15 children, 7--19 years old, with atopic disorders (normal controls). Statistically significant increases in urinary excretion of glutamine (p < 0.01), glycine (p < 0.01) and cystine (p < 0.05) were found in the MPD patients compared to the normal controls. The urinary excretion of glutamine was significantly increased while the increases in cystine and glycine excretions were non-significant when MPD patients were compared to the control patients. In addition to clinical signs and analyses of plasma and urinary phosphate, a quantitative evaluation of urinary amino acids might be a tool in the diagnosis of MPD. The significance of the increased urinary amino acid excretion in MPD is discussed.

Adult↗

The syndrome of inappropriate secretion of antidiuretic hormone. A case report.

A 72-year-old woman with the syndrome of inappropriate secretion of antidiuretic hormone of unknown cause during more than one year of observation is reported. Plasma vasopressin levels were excessively elevated, even during a water load test. Her serum electrolyte abnormalities and general state were ameliorated after fluid restriction. During treatment with demeclocycline the patient was able to increase fluid without deterioration.

Aged↗

Special considerations with regard to the dosage of tranexamic acid in patients with chronic renal diseases.

Tranexamic acid is a potent antifibrinolytic drug frequently used in the treatment of haematuria and a number of other haemorrhagic conditions. Since it is eliminated mainly in the urine, the drug accumulates in patients with uraemia. The excretion of tranexamic acid in patients with renal failure has been investigated and dosage recommendations are given for tranexamic acid therapy in cases of renal failure.

Biological Availability↗

Mild phosphate diabetes in adults.

Phosphate diabetes has been considered as rare and to occur almost exclusively in children. Upon examination of adult patients with rheumatic or kidney diseases it has, however, been found that the combination of hypophosphataemia and hyperphosphaturia is not so rare. This paper deals with 24 adult patients of this type, whom we have found during 6 months. Their mean serum phosphorus concentration was 0.7 mmol/l (range 0.5--0.8). Mean phosphate clearance was 31 ml/min/1.73 m2 (range 16--51). The diagnoses were myalgia, dorsalgia (n = 7), papillitis calcificans (n = 5), prostatitis or prostate accretions (n = 4), dizziness (n = 2), kidney stones, tubular defect, interstitial nephritis, medullary sponge kidney (1 case each), two patients had transplanted kidneys. Asthenia was a common additional diagnosis. The patients' complaints have been pain in the muscles, joints, bones (18 cases), tiredness (10 cases), dizziness (8 cases), shakyness, numbness, burning sensation (7 cases), tenderness in the muscles and bones ("the princess-on-the-pea syndrome") (7 cases). The most common findings upon examination were bone tenderness (13 cases), reduced manual power (8 cases), positive Romberg test (3 cases), slight muscle atrophy (2 cases), waddling gait (2 cases). The most common findings encountered in the laboratory, besides hypophosphataemia and hyperphosphaturia, were high pH in the urine, hyperaminoaciduria, and phosphate crystals in dried urine.

Adult↗