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Biomedical subjects

B Lindberg

Publications and source records attributed to B Lindberg.

263 records · Page 15Linked to original sources
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Placental transfer of methionine during protein restriction in the rhesus monkey studied by position emission tomography.

Four pregnant Rhesus monkeys were given a 1 week protein restricted diet with the objective to monitor possible effects on transplacental transfer of [11CH3]-L-methionine with positron emission tomography (PET). The weight was reduced in all monkeys, two of which later had an intrauterine fetal death. The mean venous serum concentrations of free methionine in the mothers were not significantly changed during the study period, although a tendency towards lower values during protein restriction was noted like in the majority of the amino acids. The uptake of trace amount of [11CH3]-L-methionine in the fetus was studied with PET before the reduced diet, after 1 week on the reduced diet and after the return to a habitual diet. Our results indicate an increase in the uptake of radioactivity in the amniotic cavity after protein restriction. The PET-technique in its present form seems to be a useful method in the investigation of transplacental transfer of several natural amino acids as well as of other compounds labelled with 11C.

Animals↗
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Medical, social and psychological factors as predictors of survival - a follow-up from 67 to 87 years of age.

All pensioners in a primary care district (n=142) participating in a multi-disciplinary population study were followed from 67 years of age to the age of 87 with regard to survival. A multivariate survival analysis of psychological and social factors and medical symptoms at 67 years of age was used to test the relationship between such data and survival. Out of the 23 original medical, social and psychological factors/variables, the successive ranking risk factors for men were: positive attitudes to old-age homes, high social class, many reported disease at age 67, low degree of need satisfaction, and many reported earlier disease. For women the ranking of risk factors for early death were: early death age of mother, low degree of social rigidity, smoking, field-dependency and need of social help. The results reflect the interplay between hereditary, medical, social and psychological factors in predicting survival and how this interplay differs between males and females.

Journal Article↗
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Carotid endarterectomy. A review of 104 operations.

A follow-up of 104 carotid endarterectomies in 90 patients is presented. The operations were performed under general anaesthesia with controlled positive pressure ventilation and with peroperative EEG-registration. The patients have been divided into four groups: Group 1: Patients with no neurological symptoms. Group 2: Patients with transitory ischemic attacks (TIA). Group 3: Patients with neurological deficits. Group 4: Patients with cerebro-lesional symptoms. The specific neurological symptoms as well as the early surgical results and the results of the follow-up are presented. An evaluation of different kinds of X-ray examinations and of EEG-registration has been performed.

Adult↗
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Acute carotid occlusion. Indication for surgery?

Six patients with acute carotid occlusion causing severe neurological deficits were operated within one to two hours after the first signs of deterioration. In one case the occlusion followed carotid arteriography and in five cases extra-cranial carotid surgery. It was possible to restore the blood flow in all six patients. In three patients the neurological deficits disappeared and in three patients they were unchanged. These cases and others reported in literature indicate that if an acute carotid occlusion is operated within one to two hours it will be possible in many cases to restore cerebral blood flow before the brain has suffered irreversible damage.

Aged↗