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Biomedical subjects

B Levin

Publications and source records attributed to B Levin.

At least 307 records · Page 17Linked to original sources

The prognosis of carcinoma of the colon and rectum complicating ulcerative colitis.

Thirty-three carcinomas of the colon and rectum occurring in patients with ulcerative colitis have been compared with matched controls from a population without colitis. There is no difference in length of survival between the patients in the two groups. More extensive tumor spread in the control group is due to the method of selection.

Adenocarcinoma↗

Ultrastructure of the "transitional" mucosa adjacent to large bowel carcinoma.

The transitional mucosa immediately adjacent to large bowel carcinoma was examined in 13 patients by scanning electron microscopy (SEM), and this was correlated with transmission electron microscopy (TEM) and light microscopy (LM). Marked abnormalities were present in this mucosa in 9/13 patients with distortion and loss of the normal architecture. Examination of adenomas showed abnormalities also to be present adjacent to the neoplastic mucosa. In all patients, the transitional mucosa was compared with two pieces of normal mucosa; in one patient, typical changes of transitional mucosa were found in this region. In the remaining patients, normal mucosa by SEM was found to consist to large deep furrows (primary crypts) as well as the crypts of Lieberkuhn (secondary crypts). The secondary crypts structure showed marked individual variation between patients but one type was present in nine patients. It is uncertain whether this is a pattern with a high incidence in the general population, or whether patients with this type of mucosa are particularly predisposed to large bowel carcinoma. SEM may, therefore, play a part in identifying patients particularly likely to develop large bowel carcinoma.

Adenoma↗

Azathioprine-associated acute pancreatitis.

Azathioprine therapy in a patient with granulomatous ileocolitis was associated with an attack of acute pancreatitis, which was confirmed by laparotomy. Recurrence of pancreatitis occurred after rechallenge with a single dose of azathioprine.

Acute Disease↗

Pancreatic cancer screening. Analysis of the problem and the role of radionuclide imaging.

The clinical, surgical, and pathologic findings in a five year prospective study of 192 patients referred with a high probability of pancreatic cancer are reported. We have defined the requirements of any pancreatic imaging procedure as its ability to distinguish a normal pancreas from pancreatic cancer or chronic pancreatitis and the capability of detecting tumors less than 5 cm in diameter. There was a 47 percent incidence of pancreatic disease (27 percent pancreatic cancer and 20 percent chronic pancreatitis). Prospective radionuclide imaging as routinely performed was found to be of little clinical value in this patient population; it was neither specific nor sensitive to pancreatic cancer or chronic pancreatitis. Preliminary data with longitudinal multiplane emission tomography show an improved diagnostic accuracy and the ability to detect resectable tumors, but its efficacy needs to be prospectively compared with other screening tests on a carefully defined patient population.

Adenoma↗

An overdenture survey: preliminary report.

The preliminary conclusions from this survey are listed: 1. The exceedingly high incidence of periodontal pathology seems to be the major problem in the long-term use of overdentures. 2. The incidence of caries is fairly low, but it remains a potential problem. 3. Subjective evaluations by the patients are favorable. 4. The overdenture technique as described by Lord and Teel seems to be practical and advantageous. 5. Additional research to find the most effective agent for inhibiting caries in overdenture support roots should be initiated. 6. Need exists for more surveys by other schools, institutions, or prosthodontists. 7. The overdenture is a valid alternative to complete denture therapy.

Adult↗

A reliable reline-rebase technique.

A reliable reline-rebase technique is very important to the general dentist. There are many excellent techniques, but this particular one has provided the most consistent results and patient satisfaction. No technique has any value unless a careful treatment plan is followed and technical procedures are performed with skill and concern.

Dental Occlusion, Centric↗

A practical questionnaire for predicting denture success or failure.

The need and value to predict success and failure in treatment of denture patients are great. The psychological and emotional factors involved are just as important as if not more important than the oral and systemic findings. The value of a simple questionnaire for the edentulous and immediate denture patients has been presented. The authors believe that all schools should present advanced information on the psychological aspects of dental care.

Consumer Behavior↗