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Biomedical subjects

B Leshin

Publications and source records attributed to B Leshin.

34 records · Page 2Linked to original sources
PubMed1992

Eyewear, cataracts, and periorbital basal cell carcinoma.

Ultraviolet exposure is an important risk factor for basal cell carcinoma. Since eyewear may have a photoprotective effect, this study evaluated the use of prescription eyeglasses and sunglasses in patients with periorbital basal cell carcinoma compared with other facial sites. There was no difference in prescription eyewear use between the groups, and only four patients in each group had regularly worn glasses since childhood. There was an increased occurrence of cataracts and cataract surgery in the group of patients with periorbital tumors, which may indicate a greater cumulative ultraviolet exposure to the orbital and periorbital sites in these patients.

Basal Cell Carcinoma↗
PubMed1991

Vulvar pyoderma gangrenosum.

Pyoderma gangrenosum is an idiopathic dermatologic disease manifested by painful cutaneous ulceration. The ulcers are characterized by their undermined, violaceous borders and necrotic tissue at the ulcer base. The lesions may have an unusual response to physical manipulation known as pathergy, a phenomenon that is manifested by rapid progression following debridement. Pyoderma gangrenosum is frequently associated with systemic diseases such as inflammatory bowel disease, rheumatoid arthritis, chronic active hepatitis and hematologic malignancies. Conservative wound care and systemic corticosteroids are usually effective therapy. We report the second case in the gynecologic literature of a patient with vulvar pyoderma gangrenosum.

Adult↗
PubMed1991

Unusual auricular complications in cutaneous oncology.

The anatomic complexity of the pinna predisposes that structure to a variety of unique, site specific postoperative complications following management of skin cancer. We describe four unusual auricular complications: 1) radiochondronecrosis; 2) autonecrosis of skin during second intention healing; 3) hearing loss secondary to tragal retraction over the external auditory canal; and 4) extension of tumor through fenestrated cartilage. Well-known postoperative auricular complications are reviewed and anticipation and recognition of these unusual complications are emphasized.

Adult↗
PubMed1991

Cryomold: a device for tissue embedding in Mohs micrographic surgery.

We describe the use of a cryomold as a technique for tissue embedding in Mohs Micrographic Surgery. This technique regularly affords many advantages over other methods of tissue embedding, such as: 1) regularly and expeditiously yields complete margins for microscopic review; 2) facilitates flattening of large, thick, and irregularly shaped specimens; and 3) avoids crush artifact and tissue distortion that may be seen with forcible compression.

Mohs Surgery↗
PubMed1990

Folliculocentric basaloid proliferation. The bulge (der Wulst) revisited.

Twenty-two patients undergoing Mohs micrographic surgery for nasal or perinasal basal cell carcinoma (BCC) were noted to have folliculocentric basaloid proliferation (FBP) on standard horizontal frozen sections. This FBP probably represents "bulge" growth and may have striking similarity to BCC. Criteria that distinguish FBP from BCC are presented herein.

Aged↗
PubMed1990

Preoperative evaluation of the surgical patient.

Both the patient and the surgeon benefit from a complete and thorough preoperative evaluation. Such evaluation may permit the surgeon to identify surgical candidates at risk for problems, institute corrective measures, and thus reduce surgical complications. Time spent by the surgeon in preoperative patient education often yields increased patient confidence and enables patients to make informed decisions about their own care. The overall result is that surgical care becomes more efficient, more pleasant for the patient, and less stressful for the surgeon.

Humans↗
PubMed1990

Radiation-induced squamous sialometaplasia.

We describe a patient with recurrent acantholytic squamous cell carcinoma following radiation therapy. Mohs micrographic sections revealed extensive squamous sialometaplasia showing striking histologic similarity to the patient's squamous cell carcinoma. Criteria necessary to differentiate squamous sialometaplasia from neoplasm are presented. This differentiation is important to ensure adequate tumor resection without unnecessary sacrifice of tumor-free tissue.

Aged↗
PubMed1989

Morphea after bromocriptine therapy.

A 57-year-old man developed morphea while taking bromocriptine. This drug is a semisynthetic ergot alkaloid, one of a class of drugs that is associated with fibrotic disorders. Other agents known for such association are serotonin (5-hydroxytryptamine) and beta-adrenergic blockers. A common pathogenesis to link these agents to fibrosis remains uncertain.

Biopsy↗
PubMed1988

Neutrophilic vascular reactions.

Dermatologic diseases are classified most commonly by morphology, by pathogenesis, or by etiology. Nontraditional classifications may be useful in terms of providing a reassessment of traditional views about disease interrelationships. This review of dermatoses characterized by neutrophilic infiltrates and dermal vessel changes reveals evidence suggesting that these dermatoses result from immune complex-mediated, neutrophil-induced dermal vessel damage. Therapeutic approaches to these heretofore unlinked dermatoses are remarkably similar.

Behcet Syndrome↗
PubMed1988

An approach to patient assessment and preparation in cutaneous oncology.

An outline of the many phases of preoperative evaluation of the dermatologic surgery patient is presented. Special emphasis is given to patient assessment and to patient preparation. The purpose of this review is not to create a compendium of steps that one must slavishly perform before each surgical procedure. Instead, it represents an effort to emphasize the importance of adequate preoperative evaluation and to discuss some of the subtleties that may be overlooked by the dermatologic surgeon.

Humans↗
PubMed1988

Carbon dioxide laser matricectomy.

We have performed a total of 13 matricectomies in 9 patients utilizing the carbon dioxide laser. To date, there have been no complications and minimal morbidity from this technique. With follow-up ranging from 8 to 24 months, no patient has experienced regrowth of nail at the treated site. In conclusion, we believe that carbon dioxide laser ablation is an effective technique for performing nail matricectomy.

Adolescent↗
PubMed1986

Lymphangioma circumscriptum following mastectomy and radiation therapy.

We describe a woman who developed clear, tense vesicles in an area of chronic lymphedema 8 years following mastectomy and radiation therapy. The vesicles showed the clinical and pathologic features of lymphangioma circumscriptum, which can develop as a late sequelae of the lymphatic damage inherent in some forms of cancer therapy.

Breast Neoplasms↗
PubMed1985

Vulvar lymphangioma circumscriptum: a rare complication of therapy for squamous cell carcinoma of the cervix.

The clinical and pathological features of a case of multifocal lymphangioma circumscriptum of the vulva are reported in a patient with chronic lymphedema of a lower extremity. Ten years previously the patient had been treated for squamous cell carcinoma of the cervix. Although lymphangioma circumscriptum is an extremely rare complication of altered lymphatic drainage, the presence of multiple noninflammatory vesicular appearing lesions in this setting should suggest the correct diagnosis.

Carcinoma, Squamous Cell↗
PubMedDate not supplied

Management of periocular basal cell carcinoma: Mohs' micrographic surgery versus radiotherapy.

In treating periocular basal cell carcinoma the goal is to achieve the most complete eradication of affected tissue while preserving as much healthy tissue as possible. In the first of these "Viewpoints" articles, Drs. Leshin and Yeatts discuss the success of Mohs' microsurgical technique (MMS) in both regards. Moreover, they note that MMS offers the additional advantage of placing all surgical and histological phases of tumor excision in the hands of one specialist, thus circumventing problems that may arise with procedures requiring the separate involvement of several specialists. In the second article, Drs. Anscher and Montana point out that modern radiotherapy techniques may offer adequate tumor control with less damage to surrounding tissues than is caused by surgical excision and reconstruction. With small lesions, radiotherapy has a success rate similar to that of surgery. With large lesions, the success rate is lower; however, if surgical excision would cause extensive disfigurement or functional damage, an initial trial of radiotherapy may be warranted, then followed by surgery, if necessary. In an editorial, Dr. Dutton summarizes the indications for and advantages and disadvantages of both techniques.

Basal Cell Carcinoma↗