Search PubMed⌕ Search

Biomedical subjects

B L Marmorstein

Publications and source records attributed to B L Marmorstein.

5 recordsLinked to original sources
PubMed1976

Interstitial lung disease in polymyositis and dermatomyositis: analysis of six cases and review of the literature.

Interstitial pneumonitis may be the presenting manifestation of polymyositis-dermatomyositis, or may occur later in the evolution of the disease. The clinical picture is characterized by non-productive cough, dyspnea and hypoxemia. The chest radiograph demonstrates interstitial infiltrates with predilection for the lung bases, often with an alveolar pattern in addition. The histopathologic features are those of organizing and interstitial pneumonitis and pleuritis, with variable fibrosis. In the present series, the patients with mixed alveolar and interstitial infiltrates on chest radiograph and organizing pneumonia and bronchiolitis obliterans in addition to interstitial pneumonitis. In one patient evolution from pulmonary inflammation to interstitial fibrosis was demonstrated. The etiology of primary lung disease in PM-DM is not known, but cell-mediated autoimmunity to an unidentified component of lung tissue is suggested. Including the present series, 50 percent of patients have responded favorably to corticosteroids with decreased dyspnea, clearing of the chest radiograph and improved pulmonary function tests.

Adult↗
PubMed1975

A new radiologic sign of subpulmonic effusion.

A new radiologic sign of subpulmonic effusion is described. That is obliteration of the intrapulmonary blood vessels which are seen below the level of the diaphragmatic dome. One hundred normal chest films are reviewed as well as nine patients with subpulmonic effusions. In three of the patients with subpulmonic effusions, this sign was the first evidence of pleural effusion.

Diaphragm↗
PubMed1975

The role of nontuberculous mycobacterial skin test antigens in the diagnosis of mycobacterial infections.

A retrospective study of 212 patients with mycobacterial infection was conducted to determine intradermal reactivity to five tuberculin units (TU) of purified protein derivative of Mycobacterium tuberculosis (PPD-S), and purified protein derivatives (PPDs) derived from non-tuberculous mycobacteria. PPDs B, Y, A, G, and F were used. The study included 138 patients with Mycobacterium tuberculosis infection, and 74 with proved nontuberculous mycobacterial infection. Eight possible patterns of skin test reactivity were discerned using PPD-S, PPD-B, and PPD-Y. In this population, selection of the largest skin test reaction within any one pattern correlated with the infecting organism in 87 per cent of the cases. Use of PPD-A, PPD-G, and PPD-F did not increase diagnostic capability. We conclude that differential skin testing with PPD-S, PPD-B and PPD-Y, is useful in the diagnosis of mycobacterial disease.

Antigens, Bacterial↗
PubMed1975

A radiographic sign of left sided mediastinal lymph node enlargement.

This report draws attention to an apparent clear space, which is normally present on routine chest posterior-anterior roentgenograms, composed of the descending aorta, pulmonary outflow tract and left upper lobe vessels which form its medial, inferior and lateral boundaries respectively. The medial margin of this space has a concave outer border. Lymph nodes of the ligamentum group lie in close proximity to this space. In the absence of other processes involving structures of the middle mediastinum, encroachment of this space from the medial direction, with formation of a convex outer border is a reliable and frequently the first radiographic sign of left-sided mediastinal lymph node enlargement.

Humans↗