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Biomedical subjects

B L Chia

Publications and source records attributed to B L Chia.

At least 37 records · Page 2Linked to original sources

Right sided chest lead electrocardiographic abnormalities in acute pulmonary embolism.

Twelve lead electrocardiograms together with right-sided chest leads V4R, V5R and V6R were recorded in four patients with acute pulmonary embolism. All four patients showed ST segment elevation and a qs or qr pattern (with prominent q waves) in one to three of the leads V4R, V5R and V6R. These abnormalities were absent in the repeat electrocardiograms which were recorded after the acute illness.

Acute Disease↗

Isolated right ventricular diverticulum with chest pain.

A 26-year-old man presented with severe chest pain. Subsequent investigations revealed a right ventricular diverticulum communicating with the right atrium. Surgery was performed, following which the chest pain disappeared completely.

Adult↗

Electrocardiographic abnormalities in right ventricular infarction associated with right bundle branch block.

An 80-year-old woman with pre-existing complete right bundle branch block presented with severe chest pain. The 12-lead electrocardiogram, together with right-sided chest leads, showed complete right bundle branch block and ST segment elevation in leads II, III, aVF, V5, V6 and V4R to V6R. These electrocardiographic abnormalities indicate acute 'Q wave' inferolateral and right ventricular infarction coexisting with right bundle branch block.

Aged↗

A case of unusual electrocardiographic presentation of right ventricular myocardial infarction.

This is a case of an unusual electrocardiographic manifestation of a patient with right ventricular (RV) myocardial infarction occurring in association with left ventricular inferoposterior myocardial infarction. There was massive ST-segment elevation in the precordial leads resembling that of an anterior myocardial infarct in addition to the ST-segment elevation seen normally in right ventricular leads. Two-dimensional echocardiography confirmed right ventricular hypokinesia and coronary angiography revealed single-vessel coronary artery disease involving the right coronary artery. It served to remind us that the presence of diffuse and massive ST-segment elevation in the precordial leads in a patient with inferior myocardial infarction may indicate simultaneous RV infarction and warrants further confirmatory tests.

Coronary Angiography↗

Two-dimensional and Doppler echocardiographic abnormalities in idiopathic dilatation of the pulmonary artery.

Although idiopathic dilatation of the pulmonary artery is uncommon, it requires to be distinguished from other important congenital heart diseases for which it may be confused clinically. We describe the two-dimensional (2D) and Doppler echocardiographic findings in two patients with this condition. Enlargement of the main pulmonary artery and right ventricle was demonstrated in both patients using 2D echocardiography. Pulmonary regurgitation was confirmed in Case 1 by both pulsed-Doppler echocardiographic and Doppler colour flow imaging studies and in Case 2 by microbubbles (which were generated from saline-injection into a peripheral vein) oscillating up and down across the pulmonary valve in systole and diastole respectively.

Adult↗

Sino-atrial Wenckebach conduction in thyrotoxic periodic paralysis: a case report.

A 28-year-old male presented with thyrotoxic periodic paralysis. On admission to hospital the serum potassium level was 1.4 mmol/l. The ECG showed classical features of hypokalaemia. In addition, sino-atrial block with Wenckebach conduction was also present. With the normalization of the serum potassium, the ECG became completely normal and showed no evidence of any arrhythmia.

Adult↗

Two-dimensional echocardiographic detection of biventricular thrombi.

A 42-year-old man presented with acute myocardial infarction. The ECG on admission to hospital showed "Q wave" inferior myocardial infarction and "non-Q wave" anterior infarction. Subsequently, he was readmitted to hospital on many different occasions for cardiac failure. About 15 months after the patient was first seen, two-dimensional echocardiogram (2D echo) showed dilatation of all 4 cardiac chambers and severe global hypokinesia of the left ventricle. In addition, a large echo dense mass was seen at the apex of the left ventricle and 2 smaller echo dense masses were present at the right ventricular apex. The echocardiographic characteristics of these 3 masses strongly suggest that they represent mural thrombi. Two-dimensional echocardiographic detection of biventricular thrombi has rarely been described in the past. This case together with the previously reported case by Friedman and Buda suggest that 2D echo may be a valuable test for the diagnosis of biventricular thrombi.

Adult↗

Simultaneous ST-segment elevation in lead V1 and depression in lead V2. A discordant ECG pattern indicating right ventricular infarction.

The major electrocardiographic change in right ventricular infarction (RVI) is ST-segment elevation in leads V4R-V6R. The authors describe a discordant electrocardiographic pattern of ST-segment elevation in lead V1 and ST-segment depression in lead V2 in five patients presenting with acute transmural (Q wave) inferior infarction and RVI. There were 51 patients with transmural inferior infarction from a thrombolytic trial. In 25 patients, the ST-segment in the right-sided precordial leads was elevated by > or = 1 mm indicating the presence of RVI. In 5 of these 25 patients, simultaneous ST-segment elevation of 1.0-8.0 mm (mean, 2.8 +/- 2.9 mm) in lead V1 and ST-segment depression of 2.5 to 4.0 mm (mean, 3.3 +/- 0.6 mm) in lead V2 were also present. The discordant pattern of the ST-segments in leads V1 and V2 is an important and specific sign for RVI.

Adult↗

Right chest electrocardiographic patterns in normal subjects.

Right-sided chest lead ECGs (V3R to V6R) were recorded in 110 normal male subjects who were between the ages of 17 and 22 years old (mean, 17.9 years). The prevalence of the rS pattern decreased from V3R (89 percent) to V6R (37 percent). However, the opposite was the case for the rSr pattern (10 percent in V3R and 36 percent in V6R). The amplitudes of the r wave, S wave and secondary r wave all progressively decreased from V3R to V6R. The prevalence of the qr and qS patterns was 0 and 1 percent, respectively in V3R and 14 and 2 percent, respectively in V6R. A positive ST segment deviation of 0.5 to 1 mm was present in 13 percent of subjects in V3R and 5 percent in V4R. T wave inversion was common and the prevalence increased from V3R (60 percent) to V6R (79 percent).

Adolescent↗

Intra-atrial smoke-like echoes and thrombi formation.

Between December 1980 and December 1987, approximately 6,000 two-dimensional echocardiographic examinations were performed in our noninvasive cardiac laboratory. During this period, five cases of intra-atrial smoke-like echoes were diagnosed. The four patients with dense smoke-like echoes in the left atria all had echocardiographic evidence of severe mitral stenosis and thrombi in the left atrial cavity, both of which were confirmed at open-heart surgery. One patient with right-sided cardiomyopathy had echocardiographic evidence of dense smoke-like echoes and thrombus in the right atrial cavity. One of our five patients was receiving anticoagulant therapy, and none had a history of thromboembolism. We conclude that using conventional two-dimensional echocardiographic techniques, smoke-like echoes in the atria are a very infrequent finding and are very commonly associated with formation of thrombi.

Adult↗