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Biomedical subjects

B Kurtz

Publications and source records attributed to B Kurtz.

68 records · Page 4Linked to original sources
PubMed1981

[Etiology of pericardial effusion following radiation therapy of Hodgkin's disease].

Radiation doses delivered to the anterior pericardium between 1969 and 1979 were ascertained in 16 patients with Hodgkin's disease, in whom pericardial effusions had developed after multiple-field therapy using 5 ventral fixed fields to the mediastinum as a supra-diaphragmatic primary treatment. The appearance of effusions was directly dependent on the dosage, if doses between 53 and 128 Gy had been delivered; in such patients, seriousness of the clinical symptoms was related to the importance of the dose delivered to the anterior pericardium. Control groups consisted of two collectives comprising 9 patients with primary pericardial affection due to Hodgkin's disease, and 11 comparable further patients without complications after mantle treatment; in these collectives, one case in the second group excepted, antisarcolemmal antibodies were not observed. On the other hand, these antibodies could be detected in 5 out of 11 patients with Hodgkin's disease who suffered from pericardial complications following radiation therapy. Possible diagnostic and pathogenetic significance of the present findings is discussed.

Adolescent↗
PubMedDate not supplied

[Computer assisted production of individual anatomic endoprostheses].

Long-term anchorage of foreign material in vital bone has proven to be the main problem in endoprosthetics. In the authors opinion, modelling of an individual anatomic anchorange component is, at present, the best way to transmit stresses harmoniously in order to utilize functional adaptation of bone and to attain long-term function. The production of a true-to-scale joint model is possible with computer-assisted-tomography. This model of a joint surface or bone canal can be used to construct an individual endoprosthesis prior to surgery. Our procedure of manifactoring a hip stem and a knee-surface-prosthesis is described.

Computers↗
PubMedDate not supplied

[How accurately can the rotation in the hip joint be estimated from ordinary plain film alone?].

Plain films were taken from 5 adults femura (with different angles of antetorsion) varying the rotation between +70 degrees to -50 degrees. An astonishingly constant relations between the structures of proximal femur and the axis of the femural condyle has been found, independent from the angle of antetorsion. According to our opinion the rotation in an adult hip joint can be estimated with an accuracy of +/- 10% from a.-p. film alone. A simple method for determining the rotation has been suggested and may be put to further discussion.

Adult↗
PubMedDate not supplied

Focal lesions of the spleen: preliminary results with fast MR imaging at 1.5 T.

Sixteen patients with splenic lymphoma and six with nonlymphomatous splenic lesions underwent magnetic resonance (MR) imaging, ultrasound (US), and dynamic CT. All patients were studied at 1.5 T with gradient echo sequences using a repetition time of 80 ms, echo time of 16 ms, and two pulse angles of 30 and 60 degrees. In 14 patients with lymphomatous lesions fast MR showed circumscribed areas of low signal intensity at both pulse angles. The lesion-to-spleen contrast was better on images acquired with a pulse angle of 30 degrees. For fast MR with pulse angles of 30 degrees, the mean lesion-to-spleen contrast was similar to US and contrast-enhanced CT. However, with fast MR the contrast showed a lower variability and was considerably better than with unenhanced CT. In one patient fast MR showed splenic involvement that was missed on both CT and US. The signal characteristics of lymphomatous, leukemic, and sarcoid involvement and of healed infarcts were similar and indistinguishable on fast MR images. Recent splenic infarctions (three cases) were, however, distinctly different, characterized by regions of high signal intensity at both pulse angles. The results of this preliminary study suggest that fast MR imaging is a promising diagnostic tool for the assessment of splenic disorders.

Diagnosis, Differential↗
PubMedDate not supplied

Dynamic sequential MR imaging of focal liver lesions: initial experience in 22 patients at 1.5 T.

The feasibility of dynamic sequential magnetic resonance (MR) imaging of focal hepatic lesions using Gd-diethylenetriamine pentaacetic acid (DTPA) was evaluated in this study. Three patients with hepatocellular carcinoma, 12 patients with metastases, and 7 patients with hemangiomas were studied with pre- and postcontrast multislice spin echo (SE) images using a repetition time of 500 ms and an echo time of 15 ms. The dynamic distribution phase of Gd-DTPA (0.1 mmol/kg) was investigated by using a sequential, transverse partial flip imaging sequence [fast low angle shot (FLASH)] before and after intravenous administration of Gd-DTPA. The lesion-liver contrast-to-noise ratio showed a great variability in patients with metastases and was significantly improved following administration of Gd-DTPA in patients with hemangiomas, two patients with hepatocellular carcinoma, and eight patients with metastases both on FLASH and SE images. Hemangiomas appeared darker than liver parenchyma on precontrast SE and FLASH images, increasingly enhanced over 5 min postinjection (pi) on FLASH images, and were still greatly enhanced at 10 min pi on SE images. During the dynamic sequential image acquisition the contrast enhancement of hemangiomas was significantly different from the enhancement observed in malignant lesions. The results of this study indicate the clinical potential of dynamic sequential imaging for the MR assessment of focal hepatic lesions.

Carcinoma, Hepatocellular↗
PubMedDate not supplied

Hypoechoic lesions without halo in echogenic liver. A frequent sonographic dilemma.

Sonographic evaluation for the presence of hypoechoic hepatic lesions without halo was carried out in 365 consecutive patients with echogenic livers. In 115 patients (31%) such lesions could be demonstrated. Computed tomography of the liver was performed in 52 of these patients, a long term sonographic follow-up in 76, and a biopsy in 3 cases. In 103 patients the hypoechoic lesions were due to sonographic pseudolesions (PL's), probably representing normal liver tissue in otherwise diffusely fatty infiltrated livers. The PL's showed characteristic sonographic appearances such as a missing mass effect, a 'landscape'-like configuration with angulated margins and slender extensions of hypoechoic tissue. The PL's were located below the capsule, near the gallbladder (41%), and ventral to the portal vein (37%). In 75 per cent they occurred in a liver with considerably increased echogenicity. In 12 patients hypoechoic lesions were caused by circumscribed malignant or infectious involvement of the liver. They could be discriminated from PL's by their mass-like appearance in 8 subjects. In 4 of these 12 cases the foci were of PL-typical appearance, but not of PL-typical location. In the light of these results and of recently published reports a rational diagnostic approach to hypoechoic lesions without halo in echogenic livers varies, depending on such factors as known primary malignancy or site of the lesion.

Diagnosis, Differential↗