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Biomedical subjects

B Kornovski

Publications and source records attributed to B Kornovski.

7 recordsLinked to original sources

[Gastric cancer. Treatment results in 237 patients].

Although current achievements of diagnostic and treatment process, including D II-III gastrectomy and neoadjuvant chemotherapy, the results from the treatment of patients with gastric cancer (GC) are still unsatisfactory. Retrospective study was performed analyzing the early and late results from the treatment of 237 pts admitted in the department with GC. 218 of them underwent operative treatment; 131 men and 87 women, aged between 26-88 years. Patients with esophageal cancer were excluded from the study. In 19 pts preoperative laparoscopy and staging of the process lead to refusal of surgery. The distribution according to clinical stage was: I st.--5; II st.--37; III st.--101 and IV st.--75 patients. Greatest importance for the exact preoperative diagnosis and staging of the process had: Fibrogastroscopy + biopsy; Ultrasonography; CT scan and Laparoscopy. Radical surgery was performed in 119 pts (54.58%). Total gastrectomy--59 /27.06%/, subtotal gastrectomy--36 /16.51%/, gastrectomy + splenectomy + pancreatic resection--14 /6.42%/; gastrectomy + hepatic resection--5; gastrectomy + hemicolectomy--2; gastrectomy + resection of c. transversum--3. The preferred method for reconstruction was Roux-en-Y. Palliative resections were performed in 18 pts. Only Gastroenteroanastomosis was performed in 41 pts. Postoperative morbidity was registered in 41 pts /18.8%/. Most common were wound complications--in 21 /9.61%/, cardio-pulmonal--14 /6.42%/, thromoemboly--3 /1.38%/. Early reoperations--13 /5.96%/ performed in 7 pts. Early postoperative mortality--7 /3.21%/, but for the radical operations it was 5.88%. The major risk factors for the postoperative morbidity and mortality were: coexisting diseases, advanced age, pancreatic resection, splenectomy and extended lymphadenectomy.

Adult↗

Changes in the electrical activity of the gastric remnant after Billroth II gastrectomy in dogs.

Chronic experiments were performed on dogs with Biller II gastrectomy followed by Roux-Y gastrojejunostomy. Gastric mucosa valve was made in the region of the gastrointestinal anastomosis in order to prevent the rapid gastric evacuation. Electrical activity of the gastric remnant, duodenum and jejunum was led off by six bipolar, silver, ball-shaped electrodes, implanted subserously on the muscle wall. Continuous bursting of groups of spike potentials with the slow gastric potentials in the usual rhythm (4.5-5 cpm) occurred during the 1st month after surgery. However, at the end of the 2nd month after surgery there were periods of tachygastria. The frequency of the gastric potentials was lower (7.52 +/- 1.37 cpm, n = 26) or higher (20.40 +/- 0.68 cpm, n = 30) compared to that of the jejunal slow waves (14.11 +/- 0.18 cpm, n = 50), i.e., it was different from the frequency of the jejunal slow waves.

Animals↗

[Manometry of the upper gastrointestinal tract in esophageal reflux disease].

Infusion manometry of the esophagus and the stomach after the permanent dynamic method of Winans [correction of Wynas] and Harris was carried out on 52 patients (30 women and 22 men) with hiatal hernia, volvulus of the stomach or peptic ulcer disease. Altogether 75 examinations were performed--35 preoperative and 40--postoperative. The mean preoperative pressure of the inferior esophageal sphincter was 9.1 (from 0 to 15) mmHg and the mean postoperative pressure was 18 (from 12 to 211 mmHg). The mean preoperative length of the inferior esophageal sphincter was 1.4 (from 0 to 4) cm and the mean postoperative length was 2.5 (from 1 to 6) cm. In 12 patients motor disturbances of the tubular esophagus were found: symmetric, hyperpersistaltic waves (Richter's nutcracker symptom)--in 3 patients, hypomotility--in 5 patients, diffuse esophageal spasm--in 4 patients. Esophageal manometry is a valuable noninvasive method for the functional diagnostic of the reflux disease and the motor esophageal disturbances as well as for the assessment of the postoperative function of the inferior esophageal sphincter.

Digestive System↗

Echinococcus multilocularis--a model for imaging research.

Magnetic resonance images of transverse, sagittal, and coronal sections of Meriones unguiculatus abdomens experimentally infected with Echinococcus multilocularis revealed alveolar cyst masses that were especially prominent in the late phase of infection.

Animals↗