Search PubMed⌕ Search

Biomedical subjects

B K Butland

Publications and source records attributed to B K Butland.

40 records · Page 3Linked to original sources

Diet and ischaemic heart disease in the Caerphilly Study.

In a South Wales Community Study, 2512 men aged 45-59 years were screened for evidence of ischaemic heart disease. Dietary questionnaires were given to all the men and, in a representative sub-sample of 665 men, 7-day weighed intake records were completed. Nutrient intakes of those who had ECG evidence of ischaemia but no symptoms were compared with those of men who had no evidence of IHD. Differences between the two groups were small. Those who had evidence of ischaemia on ECG tended to have lower intakes of energy, alcohol and most other nutrients. However, most of these differences appeared to be due to the difference in energy intake between the two groups. Allowing for the effect of differences between the groups in the distributions of age and body mass index did not alter the overall conclusions.

Coronary Disease↗

Alcohol and high-density-lipoprotein cholesterol: a randomized controlled trial.

1. A randomized controlled trial of cross-over design was set up to examine the effect of alcohol on blood lipids and certain haematological variates relevant to ischaemic heart disease. 2. One hundred subjects drank some alcohol for 4 weeks (mean intake 18.4 g/d) and abstained totally for 4 weeks, the order of these periods being randomized. 3. Alcohol appeared to produce a rise of 7% in serum high-density-lipoprotein (HDL) cholesterol, probably due to a rise in the HDL2 subfraction. 4. No significant change was detected in plasma fibrinogen or the other haematological indices. 5. These results are consistent with the hypothesis that a moderate intake of alcohol confers some protection against heart disease.

Adult↗

A randomised controlled trial to investigate the effect of a high fibre diet on blood pressure and plasma fibrinogen.

Two hundred and one subjects (147 men and 54 women) were randomly allocated to either a high cereal fibre diet or a low cereal fibre diet for four weeks. Each group then followed the alternative diet for a further four weeks. Cereal fibre intakes were 19g/d (31 g/d 21 g/d total fibre) and 6g/d (19g/d total fibre) on the high and low fibre diets respectively (p less than 0.001). Energy, protein, fat, carbohydrate, and alcohol intakes calculated from weighed intake records did not differ between the two diets, although there was a slight difference in body weight, the mean being 0.3 kg heavier at the end of the high fibre period. The high cereal fibre diet had no detectable effect on blood pressure or plasma fibrinogen.

Adolescent↗