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Biomedical subjects

B Jordan

Publications and source records attributed to B Jordan.

At least 73 records · Page 4Linked to original sources
PubMed1981

A double-blind comparison of trebenzomine and thioridazine in the treatment of schizophrenia.

Forty inpatient volunteers with diagnoses of schizophrenia were randomly assigned to treatment either with trebenzomine or thioridazine in a double-blind study of clinical antipsychotic efficacy following a 1-week placebo treatment. Psychopathology was rated using the Brief Psychiatric Rating Scale (BPRS) and Clinical Global Impression (CGI). There was a significant difference in therapeutic response to the two drugs in that psychopathology decreased significantly for the thioridazine group, but not for the trebenzomine group. Serum prolactin was elevated during treatment with thioridazine, but not with trebenzomine. Side effects were more frequently reported for the thioridazine group. These results fail to confirm previous reports of clinical antipsychotic efficacy for trebenzomine.

Adolescent↗
PubMed1977

[Fetal heart rate patterns at death in utero (author's transl)].

In a comparative description of norm- and anencephal fetus typical heart rate patterns at death in utero are demonstrated and the imminent danger is described by 5 characteristic parameters. As several figures show heart rate patterns are not influenced by fetal deformation and immaturity. The sinusoidal oscillation is not imparative in prefinal stage.

Anencephaly↗
PubMed1977

[First experiences with the Fischer-score for antepartal cardiotocograms (author's transl)].

1048 antepartal cardiotocogram of 230 pregnant women have been staged on the basis of the Fischer-Score published in April 1976. Their clinical and prognostical value has been evaluated. We compared this staging with other antepartal diagnostic parameters as there are: human-placental-lactogen, estriol and retrospectively the morphology of the placenta. Fischer-Score shows in 96,5% of all defined cases an exact and actual diagnosis of the fetal status. A Fischer-Score of 4 or less is not compatible with an improvement of the fetal status. Further stage of labour must be observed very carefully and preparations for caesarean section should be performed.

Electrocardiography↗
PubMed1970

5S RNA synthesized by Escherichia coli in presence of chloramphenicol: different 5'-terminal sequences.

Escherichia coli cells, grown in the presence of chloramphenicol, synthesize a low molecular weight RNA (CM-5S RNA) not bound to ribosomes which is similar to ribosomal 5S RNA. Oligonucleotide patterns derived from ribonuclease digests of 5S RNA and of CM-5S RNA are indistinguishable except that the 5'-terminal oligonucleotides differ. Whereas the nucleotide sequence of the 5'-terminus of normal 5S RNA is (p)U(p)G-, there are three alternate sequences of the 5'-terminus of CM-5S RNA: (p)U(p)U(p)G-, (p)U(p)U(p)U(p)G-, and (p)A(p)U(p)U(p)U(p)G-.

Autoradiography↗
PubMedDate not supplied

Technical competency in flexible sigmoidoscopy.

BACKGROUND: Family practice residencies offer training in flexible sigmoidoscopy; however, there are no objective recommendations for determining competency in learners. We describe a longitudinal study designed to determine the mean procedure time and depth of insertion for family practice residents. METHODS: During a 21-month period, data were collected for 421 patients undergoing flexible sigmoidoscopy. Second- or third-year family medicine residents supervised by family medicine faculty did all procedures. The data were analyzed with simple descriptive statistics, t test, and linear and logistic regression. RESULTS: The mean procedure time was 18+/-9.3 minutes (17.2 - 19.6, 95% confidence interval [CI]). The mean insertion depth was 51.4+/-12.4 cm (50.4 - 52.6 cm, 95% CI). Performing a biopsy was associated with an increase in procedure time (17.0 vs 27.3 minutes, P < .0001). Women with a history of pelvic surgery had less depth of insertion than did those who had no history of pelvic surgery (47 vs 53 cm, P = .002, t test). CONCLUSION: Procedural competency consists of knowledge, technical skills, and attitudes. Knowledge and attitudes can be assessed with other items, such as examinations and observation. Primary care faculty can now use these standards of insertion depth and procedure time when determining technical skill proficiency for their residents in flexible sigmoidoscopy.

Attitude of Health Personnel↗