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Biomedical subjects

B Jarzab

Publications and source records attributed to B Jarzab.

61 records · Page 4Linked to original sources
PubMed1980

Thyrotropin stimulated colloid droplet formation in the thyroid of hypophysectomised mice after calcitonin administration.

The influence of calcitonin on colloid droplet formation in the thyroid gland of hypophysectomised mice after thyrotropin (TSH) stimulation was investigated. Calcitonin was injected 30 min before TSH administration. 30 min after TSH the colloid droplet index in the thyroid cells was twice as low in the calcitonin group in comparison with the control one (0.111 +/- 0.020, 0.228 +/- 0.025 respectively). 60 min after thyrotropin treatment the number of colloid droplets was higher in the animals treated with calcitonin (0.135 +/- 0.093) in comparison with the control group (0.083 +/- 0.025). The possible mechanism of calcitonin action on colloid droplet formation is discussed.

Animals↗
PubMed1978

Changes in serum TSH level after intraventricular injection of various neuromediators in rats.

The influence of various neuromediators on pituitary TSH secretion in rats has been investigated. Noradrenaline 50 microgram/rat, dopamine 50 microgram/rat, serotonine-creatinine-sulphate 100 micogram/rat, gamma-aminobutyric acid 100 microgram/rat, pilocarpine 1 mg/rat, histamine 100 microgram/rat were administered into the lateral ventricle of the brain. All agents were dissolved in Parker's fluid. Two control groups of animals were given Parker's fluid and subjected to surgical manipulations, respectively. Plasma TSH level was estimated after 30 min by means of radioimmunoassay. The increase in the TSH level was observed after the injection of serotonine and noradrenaline (4.0 and 3.1 ng/ml, respectively) as compared with control group (0.7 ng/ml).

Aminohippuric Acids↗
PubMed1977

The effect of serotonin given into the lateral ventricle of the brain on serum TSH level in normal and thyroxine-blocked rats.

The effect of serotonin given into the lateral ventricle of the brain in rats was investigated. Serotonin was solved in artificial cerebrospinal fluid and administered in three doses: 250 microgram, 50 microgram, 10 microgram. Only the highest dose of serotonin caused a statistically significant increase in serum TSH level 0.5 h after the injection. The possible role of serotonin in the blocking mechanism of thyroid hormones on TSH secretion was also taken into consideration. 50 microgram of serotonin significantly strengthened the lowering effect of 1-thyroxine given 0.5 h before on serum TSH level.

Animals↗