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Biomedical subjects

B J Smith

Publications and source records attributed to B J Smith.

At least 235 records · Page 13Linked to original sources
PubMed1984

Health risk attitudes, beliefs and behaviors of students grades 7-12.

The purpose of this study was to identify trends for youths grades seven to 12 with respect to their attitudes, beliefs and behaviors related to smoking and weight. The results of this study indicate that the majority of students believe smoking is a real health problem. However, the strength of this belief decreases with age. The majority of students agree that smoking does not help people relax, however, the strength of this belief also decreases with age. The majority of students also agree that smoking is not socially okay and again the strength of this belief decreases with age. Another interesting finding, differing from the trends previously mentioned, is that of asking permission before smoking. It was consistent that about 75% of students at all grade levels believed that they would ask permission before smoking around others. Another finding consistently supported across the grades more than 80% believed that a separate area should be provided for those who want to smoke in buildings where smoking is permitted. Youths report a significant decline in the percent of their peers that do not smoke as grade level increases. The decline is from 76% at the seventh grade to 39% at the 12th. While students at each grade level report that approximately one-third of their mothers and 43% of their fathers smoke they also indicate that 16% of their fathers and 10% of their mothers have given up the smoking habit. Youths also consistently report that their parents would be upset if they were to smoke.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1983

A qualitative and quantitative study of subfractions of the histone H10 in various mammalian tissues.

The histone H10 was examined from seven mammalian species. All tissues were shown to contain two subfractions of H10, except for those of rabbit, in which little or no H10 was found. The subfraction composition was compared quantitatively in different mouse and hamster tissues, with the conclusion that this composition is tissue-specific. It is proposed that the wide occurrence of H10, together with the evidence of no more or less than two subfractions wherever it occurs, and the tissue-specific nature of the ratio of subfractions, signify that these two subfractions have specific individual functions.

Animals↗
PubMed1983

The effect of blister fluid from thermally injured patients on normal lymphocyte transformation.

Patients, after major thermal injury, often develop multiple in vitro immunologic abnormalities. The etiology of these immune defects is unknown, although there is evidence suggesting that these defects may be the results of circulating suppressor substance(s). To evaluate the role of the local injury in the development of immune incompetence the biologic effect of blister fluid from control lymphocyte mitogenic response to PHA was studied. Blister fluid from 35 patients, mean burn size 29% (range, 1-85% TBSA) was added to a standard lymphocyte blastogenic assay, using various concentrations of PHA (from 0.5 micrograms to 40 micrograms per well). Eight of these 35 patients (23%) had blister fluid which suppressed the control lymphocyte blastogenic response greater than 50%. Two patients with suppressive blister fluids also had suppressive serum. In contrast, only two of the nine patients whose blister fluid was not suppressive had suppressive serum. This suppressive activity was not related to bacterial contamination nor to the presence of detectable levels of endotoxin.

Adolescent↗
PubMed1983

The relationship between health risk attitudes and behaviors and parental presence.

The purpose of this study was to assess whether an association exists between a student's attitudes and behaviors about selected health risks, such as weight and smoking behavior, and the presence or absence of one or both parents. Data were collected from 5,411 central Illinois school-age youth in grades 7-12. Physical measurements were taken on all students. Also, a variety of attitudinal, behavioral and behavioral intention questions relative to risk factors including smoking and weight were developed. Comparisons for these areas were made between students identified as having both parents versus those having none or one parent. The data were analyzed using the Statistical Package of the Social Sciences (SPSS). Both a descriptive and chi-square statistical analysis were utilized. Results indicated that students with none or one parent report significantly higher health risk behaviors than students with both parents. Students with none or one parent reported being more overweight and having a significantly higher smoking rate. The students also reported significantly greater unfavorable attitudes about smoking and weight. While these findings do not imply a cause and effect relationship, it does appear that the students missing one or both parents are at much higher risk than students with both parents. This knowledge can be useful to those involved in intervention efforts. Identifying students at risk allows educators to focus their efforts on such groups. Further implications of the specific findings of this study are discussed.

Adolescent↗
PubMed1983

The relative importance of parental attitudes and behavior upon youth smoking behavior.

The purpose of the study was to assess the relative importance of parental attitudes about smoking and parental smoking behavior as factors associated with youth smoking behavior. Knowledge of the relative importance of each variable could enhance antismoking educational efforts. Data were collected from 5,409 central Illinois school-age youth in grades 7-12. Data were analyzed by sex. A variety of attitudinal, behavioral and behavior intention questions relative to risk factors, including smoking, were developed. Specific questions about parental attitudes, parental behavior, and the youth's smoking behavior were included. Descriptive and chi-square statistical analyses were utilized. Results indicate that both factors are significantly associated with youth smoking behavior. However, it appears that parental attitudes may exert a more significant impact than parental behavior. Whereas parental behavior seems to be associated with a doubling of the youth smoking rate, it appears that parental attitude is associated with an approximately fourfold increase. These results need to be interpreted within the larger context that a number of variables, and not just smoking attitudes and parental behavior have been found to be associated with youth smoking behavior. However, within this overall context it appears that parental attitude toward youth smoking is a more significant factor associated with youth smoking behavior than parental behavior. As such, those involved with youth antismoking educational efforts may find it helpful to include this factor.

Adolescent↗
PubMed1983

Measurement of plasma prostaglandin E2 using capillary gas chromatography negative ion chemical ionization mass spectrometry.

A stable isotope dilution assay for the measurement of plasma prostaglandin E2 (PGE2) employing capillary column gas chromatography-negative ion chemical ionization mass spectrometry (GC-NICIMS) is described. PGE2 was extracted from plasma using C18 and silica SEP-PAKS. Further purification and separation was accomplished by thin layer chromatography. The prostaglandin was analyzed as its pentafluorobenzyl ester-methoxime-trimethyl-silyl ether, using fragment ions at m/e 524 (protium) and m/e 528 (deuterium) for quantitation. The mean plasma concentration of PGE2 determined in 8 healthy volunteers was 2.8 +/- 2.0 pg/ml.

Adult↗
PubMed1982

Antibodies against the folding domain of histone H5 cross-react with H1(0) but not with H1.

Antibodies to the folding domain (residues 22-100) of histone H5 were elicited in rabbits. Analysis of the specificity of these antibodies by enzyme-linked immunoassay and by diazobenzyloxymethyl cellulose transfer techniques revealed that the antibody cross-reacts strongly with intact H5 and histones H1(0)a and H1(0)b purified from ox liver but not with the four core calf thymus, or with high mobility group proteins. We conclude that the globular region of H5 is serologically homologous to that of H1 degrees and suggest that possible functional similarities between the two proteins reside in this region.

Animals↗
PubMed1982

Clinical studies of protein-bound calcium in various diseases.

A recently developed gel-filtration technique allows protein-bound calcium fractions to be separated and quantitated; the protein is separated under physiological conditions of pH, temperature, and concentrations of Na, Mg, and Ca to assure that the calcium-proteinate equilibrium is not disturbed. We used this gel-filtration technique to study the protein-bound calcium fractions in 18 patients with hyperparathyroidism, multiple myeloma, diabetes, osteoporosis, or liver cirrhosis. We calculated the amount of calcium bound per gram of protein for each of the three protein peaks and the intrinsic association constant (Ka) for calcium/albumin. Results with the multiple myeloma patients (three IgG, one IgA) indicated that IgG did not bind calcium appreciably, that IgA had about the same affinity as albumin for Ca, and that Ka was slightly low for one patient of the IgG type (79 L/mol) and normal for the other three myeloma patients (106, 90, and 91 L/mol). Results for patients with the other diseases were also essentially normal, except for the osteoporesis patients (two men, one woman), whose Ka values (69, 75, and 73 L/mol) were lower than normal.

Adult↗