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Biomedical subjects

B J Shepstone

Publications and source records attributed to B J Shepstone.

53 records · Page 3Linked to original sources

Observations on the combined effect of ultrasound and certain cytoxics on the growth of the roots of Zea mays.

Seedling roots of Zea mays were used in combined treatments with ultrasonic radiation (pulsed and continuous beams) and the cytotoxic drugs vincristine and hydroxyurea respectively. It has been found that ultrasound and the above-mentioned drugs act independently of each other, a result similar to that obtained with ultrasound and X rays. This leads to the suggestion that the mechanism of damage due to the drugs is different from that due to ultrasound. An increase in drug effectiveness under the action of ultrasound has not been found.

Antibiotics, Antineoplastic↗

Observations on the combined effect of ultrasound and x-rays on the growth of the roots of Zea mays.

The roots of Zea mays seedlings were exposed to ultrasonic radiations (1 MHz) of intensities in the range of 0-1-0-8 W cm-2 (pulsed or continuous modes) for times between 2 and 60 min, together with an X-ray dose of 775 rad which was given before, after or simultaneously with the ultrasound. These experiments have shown that ultrasound and X-rays seem to act independently of each other, suggesting that the mechanism of damage due to X-rays is different from that due to ultrasound. An increase in the X-ray effectiveness under the action of ultrasound, as reported by various authors who worked with different tissues, has not been found.

Plant Development↗

Preclinical detection of metastatic melanoma.

We present a patient with melanoma in whom the performance of combined immunoscintigraphy and immunolymphoscintigraphy indicated the presence of metastatic disease 16 months before clinical manifestation. This approach may be useful in the early detection of metastatic disease and the patient presented is a lesson that cutaneous foci of uptake should not be dismissed as false-positive in the absence of clinical correlation.

Female↗