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Biomedical subjects

B J Rolls

Publications and source records attributed to B J Rolls.

At least 73 records · Page 4Linked to original sources

Effects of age on sensory-specific satiety.

The effects of age on sensory-specific satiety were investigated in adolescents (aged 12-15 y), young adults (22-35 y), older adults (45-60 y), and elderly subjects (65-82 y) (n = 24 per group). Subjects rated the pleasantness of the sensory properties and their desire to eat five foods and then ate either a fixed amount (300 g) or as much as they wanted of one of the foods (yogurt) and rerated the foods. No differences in food intake were found between the 300-g and the ad libitum experiments or among the age groups. Compared with the other age groups, elderly subjects did not show a decrease in the pleasantness of the taste of the eaten food compared with the uneaten foods in either experiment nor did the pleasantness of the texture or the desire to eat the yogurt decrease significantly in elderly subjects in the 300-g experiment. Sensory-specific satiety was pronounced in the adolescents and diminished in the elderly people.

Adolescent↗

Time course of effects of preloads high in fat or carbohydrate on food intake and hunger ratings in humans.

A high-carbohydrate (CHO) yogurt (81% CHO) and a high-fat yogurt (65% fat), containing similar levels of protein, were given in equal volumes as preloads to 14 normal-weight, nondieting males and 14 normal-weight, nondieting females. The yogurts were formulated to have similar energy densities and sensory properties, so that differences in responses to the preloads would depend on postingestive physiological effects. Three intervals (30, 90, and 180 min) between the preloads and a self-selection meal consisting of a variety of foods were utilized. The self-selection meal was served at the subject's normal lunchtime under all conditions. In the 30-min-delay condition, subjects accurately compensated for the calories in the preloads compared with a no-preload condition, but as the interval increased, compensation was less precise. No significant differences in subsequent food intake were found between the high-CHO and high-fat yogurts at any time interval. Also, there were no differences in ratings of hunger and fullness between the yogurts. The macronutrient composition of the preloads did not affect the types of foods, or macronutrients, consumed at lunch.

Adult↗

Effects of drinks sweetened with sucrose or aspartame on hunger, thirst and food intake in men.

Forty-two nondieting adult males were given 8 or 16 oz of lemonade, sweetened to equal intensity with either aspartame or sucrose, or the same volumes of water, or no drink. Subjects were separated into three groups receiving the drinks at different times: with a self-selection lunch, or 30, or 60 min before lunch. Food intakes did not differ when subjects received the drinks with lunch; however, when the calories from the drinks were included, intake was significantly greater with the sucrose-sweetened lemonades than in the other conditions. When subjects received the drinks 30 or 60 min before lunch, food intakes were not significantly different. Appetite ratings were not different among the conditions. When the drinks were consumed with the meal, the 8-oz sucrose-sweetened lemonade differed from the other drinks in that it did not significantly reduce thirst. The results indicate that in nondieting males, aspartame in concentrations similar to those in commercially available drinks did not increase hunger ratings or food intake. However, caloric drinks taken with lunch increased total energy intake in that meal. Also, sucrose-sweetened drinks may decrease thirst less than water or aspartame-sweetened drinks when taken with a meal.

Adult↗

Effects of temperature and mode of presentation of juice on hunger, thirst and food intake in humans.

Foods differ in their satiating effects; temperature and mode of presentation may be factors important for these differences. We tested the effects of these two variables in normal weight, non-dieting males and females using vegetable juice. The juice was offered as a preload, with females receiving 300 g and males receiving 400 g under conditions that systematically varied temperature (60-62 degrees C vs. 1 degrees C) and presentation (served in mug vs. bowl with spoon); a no-preload condition was also included. Each preload was followed within 5 min by a second course of grilled cheese sandwiches. In the males, intake was significantly lower after cold but not hot preloads in comparison to the no-preload condition; however, intakes following the hot and cold preloads did not differ significantly. Males also reported a significantly greater decline in thirst following the cold preloads. Temperature of the preloads did not affect food intake or thirst in the female subjects. Neither group was affected by the mode of presentation of the preloads. Further studies with other types of foods and drinks are needed to clarify whether temperature or mode of presentation can influence satiating efficiency.

Adult↗

Foods with different satiating effects in humans.

The aim of this study was to identify particular properties of foods that can affect satiety. Two levels (50 and 200 kcal) of three preloads (tomato soup, melon, cheese on crackers) were given just before two different second courses (macaroni and beef casserole, grilled cheese sandwiches), allowing us to examine the effects of caloric level, energy density, and sensory-specific satiety on food intake in normal weight, non-dieting males. Eating time and initial palatability ratings were held constant. Soup was found to reduce second course intake significantly more than the other preloads. This reduction could be partially accounted for by the low energy density of tomato soup; however, soup reduced intake more than the melon preload, which was matched for energy density. Sensory-specific satiety did not explain the satiating efficiency of the soup. Thus, during a meal, tomato soup is more satiating than the melon and cheese on crackers. Further studies are required to determine why these foods have different effects and to determine whether soup consumption can be beneficial in weight reduction programs.

Adult↗

Caloric compensation for lunches varying in fat and carbohydrate content by humans in a residential laboratory.

Two groups of three subjects participated in a residential study that assessed the effects of varying the macronutrient and caloric content of a required lunch meal on subsequent food choice and intake. Lunches contained 431 or 844 kcal, with the caloric differential created by manipulating the calories derived from either fat or carbohydrate (CHO). Each lunch condition (high-fat, high-CHO, low-fat, and low-CHO) was examined for 3 consecutive days. Subjects controlled their own patterns of food intake and could consume any item or number of items at any time during the day or night. There were no significant differences in total daily caloric intake across conditions, indicating that subjects compensated for the caloric content of the lunch regardless of the macronutrient content. Total daily caloric intake under the high-fat and high-CHO conditions was 2824 +/- 151 (mean +/- SEM) and 2988 +/- 187 kcal, respectively, whereas intake under the low-fat and low-CHO conditions was 2700 +/- 131 and 2890 +/- 247 kcal, respectively.

Adult↗

Aging and disturbances of thirst and fluid balance.

Fluid and electrolyte homeostasis depend on a balance between the intake and output of water. Aging is characterized by reduced homeostatic capacity. Changes in the control of both water intake and excretion accompany aging and may predispose the elderly to disturbances in sodium and water balance. Reduced thirst and water intake in response to water deprivation and thermal dehydration have been observed in healthy elderly persons. This reduction, combined with reduced renal water-conservation capacity, may predispose the elderly to dangerous dehydration when illness increases water losses or physical incapacity prevents access to water. The reasons for the thirst deficit are not clear. The elderly have a reduced capacity to excrete a water load, which means they are predisposed to water overload and hyponatremia. Furthermore, various neuroendocrine changes in the elderly affect fluid and electrolyte homeostasis. More studies are needed to understand the etiology of the disturbances of fluid intake and output so that they can be better prevented and treated.

Aging↗

The time course of sensory-specific satiety.

The time course of the changes in hedonic response following ingestion of three different foods was investigated. Normal weight, non-dieting female subjects rated the pleasantness of the appearance, smell, texture and taste of nine foods and then consumed as much as they wanted of cheese on cracker, tomato soup or orange jello. After this first course, subjects re-rated the pleasantness of the foods at 2, 20, 40 and 60 min. Following the 60 min rating, subjects were offered a second course of cheese on cracker or chocolate bar. For all sensory variables measured and for all foods consumed, the greatest decline in pleasantness occurred for the eaten food 2 min after consumption. For the food rate as most palatable (cheese on cracker) there was some recovery of pleasantness of the texture and taste over the hour. Intake in the second course was similar regardless of whether the food offered was different or the same as the food consumed in the first course. Since changes in the pleasantness of the foods occurred rapidly for all sensory variables studied and since the magnitude of these changes did not increase over time, it is concluded that the development of sensory-specific satiety is related primarily to the sensory stimulation accompanying ingestion as opposed to the postabsorptive effects of consuming these foods.

Adolescent↗

Hunger and food intake following consumption of low-calorie foods.

Although high-intensity sweeteners are widely used to decrease the energy density of foods, little is known about how this affects hunger and food intake. We have studied the effects of consumption of commercially available foods sweetened with either sucrose or aspartame on subjective appetite ratings and food intake. When normal-weight non-dieting males and females were given large portions of either a high- or low-calorie pudding or jello and instructed to eat as much as they liked, they ate similar weights of the different caloric versions of each food. Despite the resulting difference in caloric intake (up to 206 kcal), subjects showed only a non-significant trend towards caloric compensation when presented with a variety of foods 2 h later. Total caloric intake (preload plus test meal) did not differ between conditions. Ratings of hunger, desire to eat, the amount subjects wanted to eat, and the pleasantness of the taste of the eaten food were similarly decreased and fullness similarly increased by consumption of the different caloric versions of the foods. Awareness of the caloric content of the foods did not influence intake or appetite in that both informed and uniformed subjects responded similarly in the tests. Thus reduced calorie foods suppressed ratings of hunger for several hours after consumption, but were not associated with a significant reduction in total energy intake.

Adolescent↗

Sensory stimulation and energy density in the development of satiety.

To determine the contribution of sensory stimulation to the changing hedonic response to foods, the effects of consuming very low-calorie and higher calorie versions of soup and jello on the subjective pleasantness of foods were compared. Subjects were 24 normal weight females with low dietary restraint. Half the subjects were given test meals of low- and high-calorie tomato soup and half were given low- and high-calorie orange jello. They rated the pleasantness of the appearance, smell, texture and taste of nine sample foods as well as hunger and stomach fullness before and 2, 20, 40 and 60 min after consumption of the test meal. After the 60 min rating subjects were offered as much as they wanted to eat of a second course of cheese on crackers. Despite differences in the energy density of the test meals, there were no significant differences in the weights of food eaten in either the first or second course and no significant compensation in the second course for the energy differences of the first course. No differential effects of the caloric manipulation were observed in terms of hunger or fullness or in the development, time course and magnitude of sensory-specific satiety. That very low-calorie foods can produce sensory-specific satiety indicates that the sensory properties of foods are important for the changing hedonic response to foods as they are consumed.

Adolescent↗

The specificity of satiety: the influence of foods of different macronutrient content on the development of satiety.

The effects of consuming equicaloric preloads with different macronutrient contents on the development of satiety were investigated. Ten normal-weight, nondieting women fasted overnight and then rated hunger, fullness, and food preferences, and the pleasantness of the taste of food samples before and after five different preloads. The greatest changes in the pleasantness of the taste of the food occurred for the eaten food relative to the uneaten food. Macronutrient content of the preloads did not significantly influence the magnitude of these changes or the pleasantness of foods with similar nutrient contents. Therefore, no evidence of nutrient-specificity was obtained. Nutrient composition had a differential effect on hunger, fullness and food intake. Ratings of hunger decreased and fullness increased following the high starch and high protein preloads to a greater extent than after the high fat, high sucrose and mixed content preloads. When a self-selection meal was offered 2 hours after the preloads energy intake and preference for high carbohydrate and high fat food items were significantly decreased by the high protein and high starch preloads. However, no specific reduction in macronutrient intake was observed. In conclusion, differential effects of the preloads were observed in subjective ratings of hunger, fullness, preferences and subsequent food intake, but there was no indication that satiety was macronutrient-specific.

Adult↗

Food intake in dieters and nondieters after a liquid meal containing medium-chain triglycerides.

Medium-chain triglycerides (MCT) may be of benefit in the control of body weight by reducing food intake but this has not been established in humans. The effect of three doses (100, 200, and 300 kcal) of preloads of two complete liquid diets containing either 30% long-chain triglycerides (LCT) or 24% MCT with 6% LCT on subsequent intake was tested in dieting and nondieting females. Thirty minutes after consuming these preloads, subjects were offered a varied self-selection lunch. The major finding was that in the nondieters MCT at all doses was followed by a significantly decreased caloric intake in the lunch. Dieters were unresponsive to the type of dietary fat and tended to eat the same number of calories regardless of the preload. Although MCT can reduce short-term food intake in some individuals, further experiments are required to establish the possible benefit of MCT in weight control.

Adolescent↗

Comparison of the effects of aspartame and sucrose on appetite and food intake.

We have studied the effects of consumption of foods sweetened with either sucrose or aspartame on appetite ratings and food intake. Normal weight, non-dieting subjects ate the same amount of high- and low-calorie versions of pudding or jello and despite the resulting difference in caloric intake, showed only a non-significant trend towards compensation in a lunch one or two hours later. There were no significant differences between rated hunger, fullness, desire to eat, the amount subjects wanted to eat, or sensory-specific satiety following the high- and low-calorie foods. Knowing the caloric values of the foods did not influence intake or appetite ratings in that both informed and uninformed subjects responded similarly. Thus in the short term subjects tended to eat a constant amount of a particular food and this volume had a greater effect on appetite ratings and subsequent intake than the calories consumed.

Appetite↗

Altered water excretion in healthy elderly men.

The renal and vasopressin (AVP) response to a standard oral water load (20 ml/kg) was examined in a group of water-replete healthy elderly men (n = 6). Two groups, respectively, of water-replete and water-deprived young healthy volunteers acted as controls. After 2 h, the old group had excreted 41 +/- 2.4% (mean +/- SEM) of the water load compared to 100.7 +/- 8.8% in the water-replete young group and 70 +/- 3.8% in the water-deprived young group (P less than 0.01). Similarly, peak diuresis (7.01 +/- 0.48 ml/kg) and peak free-water clearance (5.7 +/- 0.48 ml/min) as determined from hourly sampling in the old group were delayed and significantly less than both young groups (P less than 0.01) (peak diuresis, young water-replete, 10.86 +/- 0.56 ml/kg, young water-deprived, 10.2 +/- 0.64 ml/kg, peak free-water clearance, young water-replete 8.4 +/- 0.72 ml/min, young water-deprived 9.5 +/- 0.88 ml/min). When these indices were adjusted for reduced creatinine clearance (Ccr) in the elderly, there was no significant difference between the young and old groups. Plasma AVP decreased similarly in all three groups following ingestion of water but there was no significant difference in mean plasma AVP between the young and old subjects throughout the study period. We therefore conclude that ability to excrete excess water promptly is impaired in healthy elderly men. This defect is due, at least in part, to an age-related reduction in glomerular filtration rate.

Adult↗