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Biomedical subjects

B J Mayou

Publications and source records attributed to B J Mayou.

31 records · Page 2Linked to original sources

The Laser Doppler flowmeter for microvascular monitoring: a preliminary report.

A preliminary report is presented of a free-flap monitoring technique using the Doppler shift of Laser light. It has provided useful information in five patients with free flaps. The technique is non-invasive and the apparatus is compact, portable and simple to use. Although a long term evaluation with a larger number of patients is required the technique has many advantages over others currently available and is sufficiently promising to warrant further investigation.

Blood Flow Velocity↗

Free microvascular and microneural transfer of the extensor digitorum brevis muscle for the treatment of unilateral facial palsy.

The operation of transfer of the extensor digitorum brevis muscle to the face in the treatment of unilateral facial palsy (Thompson and Gustavson, 1976) has been further modified by immediate anastomosis of its vascular pedicle to the superficial temporal vessels. Six of our ten patients showed some new movement but in only three did this approach symmetry with the other side. Long term follow-up showed that improvement can be expected for up to two years after transfer. Our technique is assessed critically and suggestions are made for further improvement.

Adult↗

An onlay vein patch technique for the repair of small vessels.

A method for the repair of defects in small blood vessels is described, using an oversized onlay autogenous vein patch tacked to the adventitia. The technique has been evaluated experimentally and it has been shown that vessels repaired with a patch remain patient with normal blood flow. By contrast, vessels repaired by direct suturing have a high incidence of mural thrombus formation and sluggish flow. The clinical usefulness of the method is illustrated by a case report describing the salvage of a free flap with a damaged vascular pedicle.

Adult↗

A new vascularized bone graft transferred by microvascular anastomosis as a free flap.

We describe a new, versatile bone and soft tissue compound free flap which may be transferred quickly and simply and describe its use in the treatment of compound fracture of the tibia and fibula with non-union due to loss of bone. The iliac crest and overlying soft tissue is transferred to the leg in one stage by microvascular anastomosis of the deep circumflex iliac vessels to vessels in the leg.

Adult↗

The length of flexor tendon grafts.

The distance between the origin of the lumbrical muscle and the insertion of the flexor digitorum profundus tendon was measured at surgery in forty-eight patients. It was found that this distance was predictable and could be estimated without measurement prior to operation. A standard technique of flexor tendon grafting is described where this distance equals the length of the tendon graft.

Hand↗

Tissue expanded free flaps.

Over the last few years there have been various reports of the use of tissue expanders as an adjunct to microvascular free transfer of tissue. This study looks at the effect of expanding the actual flap prior to transfer. Two case reports are given and it is proposed that expanded free flaps are large and thin. They have a capsule which enables them to be safely sutured under tension. They are "delayed" by the expansion process and the donor deformity is minimal. It is suggested that tissue expansion is a useful technique prior to free flap transfer for the reconstruction of large defects.

Adolescent↗

The surgical management of dystrophic epidermolysis bullosa (excluding the hand).

Fifty patients with Dystrophic Epidermolysis Bullosa (DEB) underwent surgery including release of limb, oral, anal, eye and penile contractures and treatment of chronic skin ulceration or skin tumours. Correction of contractures involves extensive release of skin and underlying tissues, with split skin grafting of secondary defects. Specific regions are discussed. Recurrence is inevitable due to ongoing disease; however, functional improvement is obtained for several years. Management of chronic skin ulceration with split skin grafting has failed to produce long term healing, with local flaps successful but limited by the problem of donor site instability. Nine of the 17 patients over 20 years of age developed squamous cell carcinomas (29 lesions), benign hyperkeratosis (9) or malignant melanoma (1) requiring excision and skin grafting or amputation of digits. Local recurrence was infrequent (3 squamous cell carcinomas), with distant metastatic spread occurring in 1 patient.

Adolescent↗

Experience in the surgical management of the hand in dystrophic epidermolysis bullosa.

Between 1981 and 1990, 45 patients (80 hands) underwent 122 hand operations, involving extensive release of contractures and pseudosyndactyly, with split skin grafting of secondary defects. Other procedures included the use of Kirschner wires, tendon release and arthroplasty. A postoperative programme of long term night splintage was employed. Finger extension was significantly improved for up to 5 years postoperatively, with a mean extension deficit preoperatively of 139 degrees, at 1 year postoperatively 60 degrees (p < 0.0001) and 4 years 84 degrees (p < 0.05). Preoperatively, pseudosyndactyly was present in 64.3% of web spaces, in comparison to 13.3% at 1 year, 37% at 4 years (p < 0.01) and 66.6% at 5 years (N.S.) postoperatively. Adduction contracture of the thumb was significantly improved for 2 years postoperatively. Functional assessment of 18 hands showed significant improvement postoperatively.

Adolescent↗