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Biomedical subjects

B J Cremin

Publications and source records attributed to B J Cremin.

At least 109 records · Page 6Linked to original sources

Congenital aganglionosis of the entire colon in neonates.

A report of six cases and their radiological diagnosis in neonates. Total colonic aganglionosis (TCA) is a variety of what is commonly known as long segment Hirschsprung's disease. This is not a rare condition, but is often unrecognized. It has a high mortality, frequently with a complicating enterocolitis. Aganglionosis of some part of the colon should be suspected in all babies who show obstructive plain film changes. In TCA the barium enema changes may easily be passed as unremarkable. However, free ileal reflux during the examination, with a transition point in the ileum, and retention of barium in the entire colon after the examination, are diagnostic.

Colon↗

The multiple sclerotic osteogenic sarcoma of early childhood.

Two cases of sclerosing osteogenic sarcoma that occurred in early childhood are reported. They and the similar cases reviewed are unusual in their development at an unusually early age, their multicentric presentation and their densely sclerotic nature. These are uncommon manifestations of osteogenic sarcoma and are considered due to proliferative metastatic osteoid formation in areas of rapid bone growth.

Child↗

The radiology of sclerosteosis.

Sclerosteosis is an unusual disorder in which increased skeletal density is associated with abnormalities of bony modelling. The condition is progressive and complications arise due to cranial nerve involvement. Death from raised intracranial pressure occurs in early adulthood. In order to define the range and extent of the bony abnormalities, the radiographic features of 18 affected individuals have been analysed. The recognition of characteristic changes permits diagnostic precision.

Adolescent↗

Biliary ascariasis in children.

The ascaris is a common human parasite and has a world wide distribution. In areas where it is endemic, biliary complications are common. In our locality it occurs mainly in children, presenting with upper abdominal colicky pain usually without jaundice. We have analyzed the positive roentgenological findings of 67 cases which presented in one year. The findings on cholangiography are diagnostic. The worm is seen as a linear translucent filling defect in a dilated common bile duct. Usually it is only faintly outlined by thin tram lines and occasionally there may not be excretion of the contrast material. The attention of radiologists is brought to this condition and the appearances of ascariasis infestation of the intestines are also noted.

Age Factors↗

Retrosternal density: a sign of pulmonary hypoplasia.

An anterior increased density, that parallels the posterior border of the sternum, was noted on the lateral radiograph of two children who were at first thought to have an accessory diaphragm. After a long follow-up and further investigations, it is now felt that this sign is solely due to upper lobe hypoplasia.

Child, Preschool↗

Paediatric renal masses. Some experiences with ultrasound and arteriography.

Renal masses in children are common, their pathology varying in different age groups. Using ultrasound to establish a diagnosis, the supine position should first be attempted. For black-and-white echography a medium frequency of 2,5 megahertz is suitable, but careful technique and interpretation are essential. Arteriography using a 70-mm camera is not suitable for selective evaluation of avascular masses. Four illustrative cases to show diagnostic points and pitfalls are recorded.

Aortography↗

Urinary ascites and obstructive uropathy.

Seven infants with urinary ascites caused by obstructive uropathy are reported. The extravasation occurs in the kidneys and produces an opaque halo, best seen in delayed films at excretory urography. The common cause is a posterior urethral valve which forms an obstructive sail-like structure.

Ascites↗

Chronic Gaucher's disease: radiological findings in 17 South African cases.

This paper reports radiological findings in a series of 17 South African patients with chronic (adult or non-neuronopathic) Gaucher's disease. Osteoarticular signs are briefly analysed on the basis of their pathogenesis. The visceral findings included an enormous calcified spleen and three cases with pulmonary lesions. Important advances have been made recently in diagnosing. Gaucher's disease and detecting carriers by demonstration of deficiency of beta-glucosidase. Radiographs are not diagnostic, but they may provide valuable clues to the nature and extent of lesions in bone, and they are essential in orthopaedic management of Gaucher's disease.

Adolescent↗