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Biomedical subjects

B J Bailey

Publications and source records attributed to B J Bailey.

17 recordsLinked to original sources

The relationship between the nasal cycle and mucociliary clearance.

Nasal airway resistances were measured bilaterally on subjects at 30-minute intervals over 6 hours using anterior rhinomanometry. The first 10 subjects found to exhibit alternating congestion and decongestion of the nasal mucosa (i.e., the nasal cycle) were included in the study. Using the saccharin method, nasal mucociliary clearance was determined for each subject in both the congested and decongested phases of the cycle. The results were statistically significant at the P less than .09 level, highly suggestive of a difference in nasal mucociliary clearance between the two phases of the cycle, with the congested phase having the more rapid clearance. However, when compared to the mucociliary clearance times in disease states, the difference in transport times between the two phases is probably not clinically significant.

Adult

Stapedectomy techniques in residency training.

The KTP-532 laser has decreased the technical difficulty involved in teaching and performing a stapedectomy in our residency program. Use of this laser has resulted in improved hearing and a decreased number of major and minor complications compared to an equal number of large fenestra stapedectomies performed with hand-held instruments. The major disadvantages of the KTP-532 laser are its cost and limited availability, and the inconvenience of a micromanipulator. The laser should not be relied upon entirely in performing a stapedotomy on a thick footplate. The University of Texas Medical Branch experience in training residents in both large and small fenestra stapedectomy is reported.

Adolescent

Short stature and school performance--the Wessex Growth Study.

The relationship between short stature and school performance was examined by comparing an unselected cohort of 140 'normal' short children (below 3rd centile) aged between 7 and 9 years with 140 control children of normal height (10th-90th centiles). The short children had unimpaired self-esteem and normal patterns of behaviour, but a tendency towards hyperactivity and poor concentration. Their IQ scores were normal, but attainment, especially in reading, was low. The underachievement observed in the short children is largely due to the low socio-economic status of this group. All the children in the study were prepubertal and these data will serve as a baseline for further follow-up during and after puberty.

Body Height

Maxillofacial injury.

This chapter has emphasized the relative infrequency of severe skeletal maxillofacial injuries in children. When they do occur, it is extremely important that they be approached by a team of physicians, each of whom is competent to manage the injury and complications related to his specialty. Particular attention must be given to the issues of general facial bone growth as well as future dental development. All operative procedures must be designed to avoid further injury to unerupted teeth, and the traditional methods of immobilization must be modified in order to avoid the avulsion of deciduous teeth.

Child

Olfactory neuroblastoma. Management and prognosis.

Olfactory neuroblastoma is an uncommon malignant tumor originating in the olfactory epithelium in the roof of the nose. It usually produces nasal obstruction and secondary sinus disease and is often mistaken by the physician for a nasal polyp. Olfactory neuroblastoma has been observed to cause death by distant metastasis or by invasion through the cribriform plate and secondary meningitis in most instances, and is generally associated with a low cure rate. During the past eight years, we have treated three patients with olfactory neuroblastoma by a combination of extensive local surgery using the lateral rhinotomy approach with ethmoidectomy and medial partial maxillectomy, combined with either preoperative or postoperative irradiation therapy. From a review of the literature we have tried to draw meaningful conclusions regarding treatment.

Adult

On estimating the frequency of a recessive gene in a random mating population.

The maximum likelihood estimator of the frequency of a recessive gene in a random mating population is simply the square root of the proportion of recessive individuals in a random sample. However, its asymptotic variance, i.e. the inverse of Fisher's information, has an unexpected functional form, and its use may lead to incorrect inferences. An explanation for this is sought by deriving an expansion for the exact variance of the estimator. Further, a number of calculations reveal conditions under which the asymptotic variance provides a reasonable approximation to the exact variance. Lastly, the problem of setting confidence limits to the gene frequency is discussed, with a number of approximations being considered.

Gene Frequency

Glottic reconstruction after hemilaryngectomy: bipedicle muscle flap laryngoplasty.

This paper presents the techniques for glottic reconstruction after partial laryngectomy using a bipedicle muscle/perichondrial flap. The use of this technique extends the scope of lesions amenable to conservation surgery and maximizes the postoperative laryngeal function in terms of satisfactory phonation, respiration, and deglutition.

Drainage

Otolaryngology.

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Acupuncture Therapy

An implanted electronic laryngeal prosthesis.

The authors present a preliminary progress report on their investigations dealing with the development of an implanted electronic laryngeal prosthesis system. Their initial observations indicate success in the design and fabrication of the implantable, retropharyngeal transducer and secondary induction coil elements. The surgical procedure for implantation is described, and the complications encountered during the first thirteen procedures are reported. These complications included five seromas, one postoperative abscess, one partial wound breakdown secondary to animal-inflicited traumn, and two anesthetic deaths at the time of follow-up radiographic procedures. Additional observations are presented regarding the acoustical output of the transducer in air and after implantation. Projections are made concerning the use of this laryngeal prosthesis system in human patients for vocal rehabilitation after total laryngectomy.

Animals