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Biomedical subjects

B Ia Bart

Publications and source records attributed to B Ia Bart.

At least 19 recordsLinked to original sources
PubMed2002

[Experience of the use of nebivolol in the treatment of hypertension in postmenopausal women].

Nebivolol was given to 30 hypertensive postmenopausal women as monotherapy (5-10 mg/day) or in combination with hydrochlorothiazide. Clinical effect was achieved in 76.6 and 86.7% of women on mono- and combination therapy, respectively. Hypotensive effect was confirmed by 24-hour blood pressure monitoring. Blood pressure lowering was associated with decrease of total peripheral resistance and regression of left ventricular hypertrophy. Nebivolol appeared to be metabolically neutral and only sporadic adverse effects were registered.

Analysis of Variance↗
PubMed2001

[Effective treatment of cardiac failure with caposide at an outpatient clinic].

AIM: To evaluate results of long-term outpatient use of caposide in patients with cardiac failure. MATERIAL AND METHODS: 74 patients (59 males and 15 females aged 40-76 years) with chronic cardiac failure (CCF) received caposide in individual doses. CCF was caused by ischemic heart disease (IHD) and dilated cardiomyopathy in 65 and 9 patients, respectively. The treatment effect was assessed by changes in clinical symptoms, quality of life and physical activity. RESULTS: Clinical symptoms, functional class of IHD, exercise tolerance and quality of life improved. Serious side effects were absent. CONCLUSION: Caposide can be considered as first-line therapy in outpatient treatment of patients with CCF of different severity as monotherapy and adjuvant in combined treatment.

Aged↗
PubMed1997

[The therapeutic and prophylactic use of Olicard-Retard under outpatient polyclinical conditions in stenocardia patients].

Olicard-Retard, isosorbide-5-mononitrate drug, has been tried in a single daily dose 40 mg in 60 outpatients with angina pectoris. The drug reduced the frequency of anginal attacks and nitroglycerine intake in most of the patients. The antianginal properties were combined with anti-ischemic effects as shown by echocardiography. Side effects (head ache) were mild. Olicard-Retard proved effective in angina of effort both in monotherapy and combined treatment.

Aged↗
PubMed1997

[A trial of the long-term use of Sedacorone (amiodarone) under polyclinic conditions for the prevention of paroxysms of atrial fibrillation].

Sedacorone (amiodarone) was given to 70 outpatients with coronary heart disease for 1.5-2 years to prevent paroxysms of cardiac arrhythmia after recovery of sinus rhythm. Sedacorone was administered initially in the dose 600 mg/day for 10-12 days, then the dose lowering was adjusted to the tolerance, heart rate and ECG readings. The minimal dose of 200 mg/day was taken for 5 days a week with a 2-day interval. In adequate individual dose Sedacorone prevented paroxysms of cardiac fibrillation or made the paroxysms less frequent in 91.4% of patients. Careful selection of patients and regular control helped avoid serious cardial and extracardiac complications. Sedacorone is recommended as a first-line medicine for outpatients with frequent paroxysms of cardiac fibrillations after recovery of the sinus rhythm to prevent the paroxysms recurrences.

Aged↗
PubMed1996

[The use of the cephalosporin antibiotic Zinnat under polyclinic conditions in treating patients with bronchopulmonary infections].

The cephalosporin antibiotic zinnat was given to 171 outpatients with bronchopulmonary infections. Pneumonia patients received 500 mg, patients with acute bronchitis or exacerbation of chronic bronchitis 250 mg twice a day. The recovery was registered in 97.7, 98.8 and 91.8% of patients, respectively. The drug proved effective, low-toxic, convenient in use. Wide-spectrum action, significant activity against both gram-positive and gram-negative pathogens make zinnat a promising drug for outpatient treatment of bronchopulmonary infections.

Acute Disease↗
PubMed1995

[The diagnostic importance of different study methods in the recognition of renovascular hypertension at the prehospital stage].

A comparative study of diagnostic potential of excretory intravenous urography, radionuclide renography and angionephroscintigraphy, renal ultrasonography and ultrasonic dopplerography of renal arteries in prehospital examination for renovascular hypertension made it possible to give preference to the above dopplerography. The latter is able to provide reliable data on renal artery stenosis and genesis of arterial hypertension.

Adult↗
PubMed1995

[A comparative study of the expression of activation markers on T-lymphocyte subpopulations in different forms of bronchial asthma].

In this study we investigated a phenotype of intact and PHA-stimulated T-lymphocytes from peripheral blood of patients with allergic and nonallergic asthma. Expression of the activation markers (CD25, CD71, HLA-DR) on subsets of T-lymphocytes (CD4+ and CD8+) was determined using double-colour flow cytometry. It was found that nonallergic patients had increased percentages of CD4+CD25+, CD8+CD25+, CD4+HLA-DR+, CD8+HLA-DR+ cells. Allergic patients had a significant increase of CD4+CD25+ cells only. To examine functional significance of these changes mononuclear cells were cultivated with PHA in vitro. Thus, our findings improve our knowledge about asthma pathogenesis and create the grounds for pathogenetically validated immunocorrection.

Adult↗