[Comparative characteristics of hemodynamic changes in man and animals after intravenous administration of noradrenaline].
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Biomedical subjects
Publications and source records attributed to B I Tkachenko.
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In acute experiments on cats, administration of hexonium (2 mg/kg) abolishes constrictory responses of the spleen resistance vessels in pressory sinocarotid reflex while the constrictory and dilatory responses of the capacitance vessels are preserved. Simultaneously, the high amplitude (over 15 mcV) sympathetic discharge is abolished in the spleen nerves which suggests its connection with the resistance vessels' responses, and the low-amplitude (up to 15 mcV) discharges are preserved. The reflex changes of these discharges' frequency are correlated in direction with the reflex responses of the capacitance vessels.
In acute experiments on cats, the diameter changes of the arterio-venous anastomoses in a number of vascular zones and their shunting coefficient were studied under the pressor reflexes; the method of injections of the microspheres was used. In these experiments the shunting capacity of the arterio-venous anastomoses was shown to be decreased in the small intestine, the spleen, the kidney and the gastrocnemius muscle under the pressor synocarotid reflex and the electrical stimulation of the somatic afferents.
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