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Biomedical subjects

B I Sanin

Publications and source records attributed to B I Sanin.

8 recordsLinked to original sources

[Clinical significance of cellular and humoral immunity in tropical malaria].

Humoral and cellular immunity were studied in 34, 59 and 21 patients with mild, moderate and severe tropical malaria in the course of the disease. It was found that immunological indices in tropical malaria change with the disease severity. Some immunological indices may be indicative of the infection severity, outcome and prognosis of the disease and contribute to more effective chemotherapy and immunocorrection.

Adult↗

[Profiles of serological markers of HBV-infection in acute hepatitis B].

The authors demonstrate that severe and fulminant forms of acute hepatitis B (AHB) are associated with low concentrations of HBsAg and anti HBs in peripheral blood. In the majority of cyclic AHB cases HBeAg is registered in the serum for 2-3 weeks, whereas in more severe course of AHB its indication is shorter, with occasional occurrence of serological window. The more severe and longer was AHB course the lower was concentration of HBsAg in peripheral blood. The assessment of the complete profile of serological markers of HBV infection and HBsAg concentration in the serum in the course of the disease will promote more effective diagnosis of the disease pattern and outcome.

Acute Disease↗

[Microcirculatory function in viral hepatitis A and B].

Microcirculation was studied over time in 51 patients with acute viral hepatitides types A and B using bulbar microphotographic vasography. The results were compared with some immunological indices (the blood level of circulating immune complexes, the platelet aggregation test). The expression of microcirculatory changes correlated both with a type of virus hepatitis and the severity of disease. The relationship of disorders in the system of microcirculation with immune factors, in particular with immunopathological reactions developing during HBV infections, was discussed.

Adolescent↗