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Biomedical subjects

B I Rose

Publications and source records attributed to B I Rose.

20 records · Page 2Linked to original sources

Use of a single intrauterine insemination of defrosted cryopreserved sperm for therapeutic donor insemination.

OBJECTIVE: To evaluate the efficacy of a protocol employing defrosted cryopreserved sperm as a single well-timed intrauterine insemination. DESIGN: A retrospective observational study. SETTING: A university fertility service and a private fertility practice located in small metropolitan areas. PARTICIPANTS: All 138 donor sperm recipients (348 cycles) treated on this protocol by the author during a 27 month period were evaluated. All 86 patients (200 cycles) treated using intracervical inseminations bracketing the time of ovulation during the same time period were also evaluated. RESULTS: A single well-timed intrauterine insemination had an associated pregnancy rate of 13.8% per cycle. In contrast, intracervical inseminations bracketing the time of ovulation had an associated pregnancy rate of 5% per cycle (P < .005). CONCLUSIONS: A single well-timed intrauterine insemination of defrosted cryopreserved sperm is more efficacious and less expensive than intracervical inseminations bracketing the time of ovulation.

Cryopreservation↗