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Biomedical subjects

B I Rees

Publications and source records attributed to B I Rees.

51 records · Page 3Linked to original sources

Observations on the muscle abnormality of the human sigmoid colon in diverticular disease.

1 Pharmacological experiments were performed on circular and longitudinal muscle strips of sigmoid colon from diverticular disease specimens, and their responses compared with those of similar muscle strips from sigmoid colon resected from carcinoma (control). 2 The longitudinal muscle strips from diverticular disease specimens were significantly less responsive to acetylcholine, histamine or noradrenaline than control longitudinal muscle strips. 3 The responses of the diverticular circular muscle strips showed a small decrease to acetylcholine, a small increase to noradrenaline and no change to histamine when compared to control strips.

Acetylcholine↗

Non-operative removal of retained stones in the common bile duct.

A method of removal of retained common bile duct stones under radiological control is described and its use in 16 patients reported. The ease of the method, the minimal associated morbidity and the inexpensiveness of the equipment suggest that this should be the primary method of removal of retained stones when a T tube has been placed into the common bile duct.

Adult↗

Low dose steroids and clinical relapse in Crohn's disease: a controlled trial.

The long-term effect of prednisone in Crohn's disease has been examined in a double-blind controlled trial. Clinical relapse, recurrence, and extension of the disease were examined in 64 patients followed-up for up to three years. Fourteen patients were withdrawn because of severe symptoms (eight on prednisone and six controls); the withdrawal rate in both groups was 30% at three years. Nine other patients had radiological recurrence or extension of disease (five prednisone and four controls). Prednisone did not improve the relapse rate, nor did it affect recurrence or extension of disease.

Adolescent↗

Nipple retraction in duct ectasia.

Thirty patients with nipple retraction associated with duct ectasia have been studied to determine the clinical features of this condition. This association is a common one and the similarity of these nipple changes to those produced by cancer is emphasized. While clinical evaluation of the nipple changes may give an indication of the diagnosis, it is by no means absolute and mammography is advocated in all cases. Combined clinical and mammographic assessment will allow confident differentiation of the two causes in many cases, and a policy for management of nipple retraction is presented.

Adult↗

Chronic intussusception in children.

Three children with chronic intussusception are reported together with a review of the literature. Neither the palpation of a mass nor the passage of blood per rectum was necessary for the diagnosis. Weight loss was seen in each case and 1 child was investigated for malabsorption. In all 3 children there was a delay in diagnosis, and it is suggested that a chronic intussusception should be considered more frequently in children with persistent abdominal symptoms for which no cause can be found. Although a barium enema was helpful diagnostically, it did not result in the reduction of the intussusception. The problem of a recurrence after a reduction and its subsequent management is discussed.

Child, Preschool↗

Secondary involvement of the penis by rectal cancer.

Two cases of metastasis to the penis from a primary rectal carcinoma are described. The clinical features, treatment and prognosis together with the probable modes of metastasis are discussed. All previously reported cases of penile metastasis from the rectum are reviewed. It is suggested that contrary to previous reports that prognosis is not uniformly poor and hence a more aggressive attitude to treatment should be adopted. Metastatic lesions in the penis should also be considered as a cause of urinary obstruction following abdominoperineal excision of the rectum.

Adenocarcinoma↗

Ureteric obstruction due to sigmoid diverticulitis.

Two cases in which the ureter was obstructed by an inflammatory diverticular mass are presented. The difficulties of distinguishing such a mass from a carcinoma both clinically and at operation are emphasized. In order to minimize the risk of ureteric injury and to facilitate planning of the operative procedure, it is recommended that intravenous pyelography should be performed before resection of a suspected diverticular mass.

Aged↗

Laparoscopic cholecystectomy.

The technique of laparoscopic cholecystectomy is probably the most significant major surgical advance of the last decade. It allows shorter hospitalization, rapid recovery and early return to work. Significant financial savings may be achieved over current conventional treatment. In this article the procedure is reviewed and its advantages and drawbacks are discussed.

Cholangiography↗

Laparoscopic colectomy.

Recent interest in laparoscopic surgery has led to an increasing number of procedures being performed by minimally invasive techniques. Initial experience with laparoscopic cholecystectomy and advances in instrument design and surgical technique have enabled more sophisticated procedures such as laparoscopic colectomy to be performed.

Colectomy↗