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B Hindman

Publications and source records attributed to B Hindman.

5 recordsLinked to original sources
PubMed1995

Con: glucose priming solutions should not be used for cardiopulmonary bypass.

In conclusion, the advantage of glucose-containing CPB priming solutions are quite modest. In contrast, the weight of current evidence strongly supports the notion that hyperglycemia is far more likely to be detrimental than beneficial to a brain challenged by ischemia, especially when there is reperfusion (hypotension or circulatory arrest) or when the brain is normothermic. Because neurologic complications pose such a serious threat to cardiac surgery patients, avoidance of hyperglycemia during surgery and CPB seems prudent at this time. Hence, CPB priming solutions should not contain glucose.

Cardiopulmonary Bypass↗
PubMed1994

Cerebral physiology during cardiopulmonary bypass: pulsatile versus nonpulsatile flow.

In summary, neurological injury continues to be a significant source of perioperative morbidity and mortality in cardiac surgical procedures. To reduce the incidence and/or severity of these complications, a better understanding of the cerebral physiology of CPB is needed. Specifically, it is important to determine how the conduct of CPB either contributes to or modifies the response of the brain to neurological insults. Our research indicates that, in the uninjured brain, nonpulsatile perfusion per se does not appear disadvantageous in terms of brain blood flow or oxygen metabolism at 27 degrees C. Conversely, pulsatile perfusion does not appear to confer any special benefits. Whether pulsatility might influence neurological outcome in the presence of an ischemic insult remains to be determined.

Animals↗
PubMed1986

Role transition.

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Education, Nursing, Baccalaureate↗
PubMedDate not supplied

Mechanisms of perioperative cerebral infarction.

Perioperative cerebral infarction occurs in less than 1% of general surgical procedures; the mechanism is usually unknown. The clinical features of 12 consecutive perioperative strokes were retrospectively reviewed. Although intraoperative hypotension was frequent, onset of deficit occurred postoperatively in 83% and intraoperatively in 17%. Cardiogenic embolism was a common cause of stroke (42%), with atrial fibrillation present in 4 patients (33%) at the time of stroke. The potential roles of hypercoagulability, hypotension and carotid occlusive disease are discussed. Future reports concerning perioperative stroke should consider the multiple mechanisms and temporal relationship of stroke to the operative procedure.

Aged↗