Biomedical subjects

B Heublein

Publications and source records attributed to B Heublein.

At least 91 records · Page 5Linked to original sources

PubMed1983

Detection and quantification of left main coronary artery stenosis by two-dimensional echocardiography.

This study was undertaken to determine the diagnostic feasibility of detecting both qualitatively and quantitatively stenotic wall abnormalities in the left main coronary artery (LMCA) and its bifurcation. Adequate two-dimensional echocardiographic (2DE) images of the LMCA were obtained in 18 of 20 patients with angiographically proven coronary artery disease (CAD). In 15 of 18 patients the LMCA was completely imaged but in different 2DE-planes in most of the cases. Only in 4 of 18 patients could adequate images of the bifurcation, including the central parts of left anterior descending and circumflex branches, be demonstrated. On the contrary, the 2DE detected calcification of the LMCA identified by fluoroscopy in only 2 of 5 patients. As to quantitative analysis, the correlation of luminal diameters in stenotic and non-stenotic coronary artery obtained from 2DE and coronary angiography was satisfactory (r = 0.69, p less than 0.01). These results suggest that 2DE can be useful for the follow-up study of LMCA disease. However, this method is not indicated for the detection of more distal left coronary artery stenosis occurring beyond the bifurcation.

Adult↗

PubMed1980

[Function of the left ventricle in pacing-induced angina pectoris].

In 48 patients with angiographically ascertained coronary arteriosclerosis and 15 patients with unconspicuous cardiac findings a complete pressure-flow-volume-analysis of the left ventricle in rest and under artificial atrial tachycardia (atrial pacing) was carried out. In 26 patients with coronary arteriosclerosis a typical angina pectoris could be induced, however, in this group a specific constellation of the findings of the initial values was not present. Under influence of angina pectoris an increase of the disturbances of the regional contraction, connected with a significant decrease of the ejection fraction and of the isovolumetric contractibility parameter Vpm. Apart from this a significant increase of the enddiastolic ventricular pressure and of the quotient deltaP/deltaV in the diastole as a sequel of a decreased distensibility of the ventricle was found. In one part of the patients as an expression of the efficacy of the Frank-Starling-mechanism also the enddiastolic volume increased. Altogether a broad spectre of the functional changes was the result, the direction and degree of severity of which could not be foreseen according to the adequate findings in rest.

Adult↗

PubMed1975

[Hemodynamics of the left ventricle during myocardial infarct].

It is issued from the fact that in acute myocardial infarction depending on expansion and localisation of the necrosis, on the degree of the possible functional adaptation of the not-affected myocardium or its previous injury must be reckoned with different changes of the haemodynamics. The sufficient judgment of the function of the left ventricle which is necessary for a differentiated therapy is possible only by the combination of several haemodynamic parameters. First results of direct measurements of pressure and volume of the left ventricle in patients with acute myocardial infarctions are demonstrated. Two types of haemodynamic constellation and their therapeutic influence are demonstrated. By the provable applanation of the functional curve of the left ventricle a change of the optimum working points develops; a secure differentiation between the reduction of the contractile function and reduced diastolic distensibility, however, is not only given on account of the displacement of the functional curve of the left ventricle. The results show that for a haemodynamic monitoring apart from the direct or indirect determination of the filling pressure of the left ventricle a practicable measurement of the cardiac output which must be repeated several times is necessary for an aimed therapy from haemodynamic aspects.

Blood Pressure↗

PubMed1975

The value of quantitative apex-cardiography as compared to intracardiac functional diagnostics of the left ventricle.

A quantitative procedure of recording the apex impulse as regards its duration, force and rate of development of force requires a DC amplification ensured by a semiconductor strain-gauge transducer. In addition, impact and diameter or stamp and internal diameter of the contact ring must be defined. Comparative measurements show a good correlation between timing, absolute values and the first derivatives.

Cardiac Catheterization↗

PubMed1975