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Biomedical subjects

B Henry

Publications and source records attributed to B Henry.

At least 91 records · Page 5Linked to original sources
PubMed1988

Nursing administration research in hospitals and schools of nursing.

"Nursing service administration is in the most desperate need of research..." So said Herman Finer, well-known professor at the University of Chicago and in 1952, director of the Kellogg Nursing Service Administration Research Project. Today, 35 years later, the same need holds true. Administrators in hospitals and schools of nursing were canvassed to discover the nature of nursing administration research already in progress. Information about what is being studied, and amounts and sources of funding can be useful to nurse executives who are planning to implement research projects that build on existing knowledge. Findings from the study can also contribute to development of an overdue national research agenda for nursing administration.

Administrative Personnel↗
PubMed1987

Language, leadership, and power.

Analysis of language people use at work is an important way of making sense of what goes on in organizations. Words captivate and compel, or hobble and bag. Recognizing the variety, distribution, and relevance of language can help nurse executives understand the subtleties of leadership, varying dimensions of power, and paradoxes of organizational life.

Administrative Personnel↗
PubMed1983

Binding of proteins from the large ribosomal subunits to 5.8 S rRNA of Saccharomyces cerevisiae.

Specific binding of purified proteins from the large ribosomal subunits of Saccharomyces cerevisiae to 5.8 S rRNA was examined by three different methods: nitrocellulose membrane filtration, sucrose density gradient centrifugation, and RNA-Sepharose column chromatography. RNA-protein complex formation was proportional to the amount of proteins added to the reaction mixture. The binding of proteins to the RNA could be saturated. Such RNA-protein complexes were isolated on sucrose density gradients. Protein species present in these complexes were isolated, iodinated, and analyzed by two-dimensional polyacrylamide gel electrophoresis. Eleven proteins, L13, L14, L17, L19, L21, L24, L25, L29, L30, L33, and L39, were identified. By comparison, only six proteins interacted with the 5.8 S rRNA-Sepharose under similar ionic conditions. They were proteins L14, L21, L24, L27, L29, and L30. To better characterize these binding proteins, the interaction of individual proteins with 5.8 S rRNA was studied by nitrocellulose membrane filtration. Proteins L14, L19, L21, L29, L33, and L39 were observed to bind individually with 5.8 S rRNA. Binding of each protein to the RNA could be saturated. The apparent association constants (K'a), measured at 4 degrees C and in 30 mM Tris-HCl, pH 7.4, 20 mM MgCl2, 330 mM KCl, and 6 mM beta-mercaptoethanol, ranged from 1.05 to 3.70 X 10(6) M-1.

Chromatography, Affinity↗
PubMed1983

Epstein-Barr virus transcription in nasopharyngeal carcinoma.

Sequences which encode Epstein-Barr virus (EBV) RNA in nasopharyngeal carcinoma (NPC) tissue have been identified. We utilized human biopsy material directly as well as NPC grown in nude mice. Total RNA was extracted from the tumor material and separated into polyadenylated and nonpolyadenylated fractions by oligodeoxythymidylate-cellulose chromatography. This material was used as template to construct 32P-labeled cDNA. The labeled cDNAs were hybridized to Southern blots of recombinant EBV DNA fragments. Three of the biopsies, F, 49, and 55, contained polyadenylated RNA homologous to the EBV BamHI fragments V and K, and EcoRI-DIJhet. These same fragments encode the most abundant polyribosomal RNAs in latently infected lymphoblastoid cell lines. The sequences which encoded nonpolyadenylated RNA in NPC tumor 49 were more extensive and included BamHI fragments C, V, B, E, and K, and EcoRI fragments DIJhet, E, F, and G1, a result that indicates selective polyadenylation in EBV RNA processing. A fourth biopsy, NPC tumor 18, contained polyadenylated RNA homologous to the BamHI fragments H, B, K, Y, B1, I1, and A and EcoRI fragments F and G2. A similar pattern of transcription was identified in three tumor specimens from nude mice, 4, 5, and 8. Transformation of lymphocytes did not occur after cocultivation in vitro with explants from these nude mice tumors. This transcriptional pattern may represent an activated state of the EBV genome, formerly not detected in tumor tissue, which is analogous to the state of abortive infection identified in induced in vitro cell systems.

Animals↗
PubMed1983

[Diagnosis and therapy of temporomandibular dysfunctions. The experience of the Clinique de Stomatologie et de Chirurgie Maxillo-Faciale de Lyon].

Temporomandibular dysfunction is a relatively frequent disorder, affecting mainly young women, that remains a poorly recognized entity. Clinical symptoms usually associate pain and cracking of the jaw, frequently accompanied by limitation of opening of the mouth. Occlusal injury is the cause of the dysfunction in every case. Two panoramic radiographs, one in the usual terminal occlusion and the other with the mouth open, provide evidence of the amount of condylar movement and the morphology of the condyles. Active mandibular movements provide muscular re-education. The inhibitors of occlusion (palatine plate to increase incisor elevation or covering plate) have the objective of reducing muscle spasm. Treatment of the cause of the disorder is based on occlusal rehabilitation, surgery of the temporomandibular joint being doomed to failure as it attacks the consequences and not the origin of the occlusal dysfunction.

Dental Articulators↗
PubMed1982

Binding of rat ribosomal proteins to yeast 5.8S ribosomal ribonucleic acid.

5.8 S RNA-protein complexes were prepared using purified yeast 5.8 S RNA and proteins from the large ribosomal subunit of rat liver. Formation of such hybrid complexes, as measured by Millipore filtration, was dependent on protein concentration. Binding of proteins to the RNA could approach saturation. Such complexes were isolated from sucrose density gradient centrifugation and shown to contain proteins L6, L8, L19, L35 and L35a. These proteins were identified by their molecular weights on polyacrylamide gels containing dodecylsulfate and their mobilities on two dimensional polyacrylamide gels.

Animals↗
PubMedDate not supplied

Biological fate of a polydisperse acrylate polymer in anaerobic sand-medium transport.

Soluble polyacrylate (PA), a polydisperse mixture of polyacrylate polymers, is strongly adsorbed and biodegradable. Biotic fate studies were carried out with once-through columns containing sand colonized with anaerobic biomass previously grown in a methanogenic fluidized bed. A fraction of soluble PA having a weight-average molecular weight of 16,700 and a range of molecular weight from 10(3) to 10(5) was biologically removed and mineralized to CO2. Due to its polydisperse nature, the breakthrough curve had a gradual increase to an apparent steady-state removal of approximately 60% near one day when the liquid detention time was 21 minutes. Modeling successfully explained the observed breakthrough result when the fraction was divided into components having a wide range of retardation factors (R): about 25% was strongly adsorbed (R = 200 and 500), 45% was moderately adsorbed (R = 50 and 100), and 30% was weakly adsorbed (R = 1-10). In this study, in which active biomass already was present from utilization of a primary substrate (glucose here), equilibrium adsorption increased the time to breakthrough, which also reduced the exiting concentration by increasing the substrate contact time.

Acrylic Resins↗
PubMedDate not supplied

Biodegradation and sorption properties of polydisperse acrylate polymers.

Polyacrylate (PA), which is widely used in disposable diapers, is synthesized by polymerization and cross-linking of acrylate. During the synthesis, 3-6% of the polyacrylate polymers is not incorporated into the absorbent material, but remains soluble. If the soluble PA is mobilized from a landfill, it could enter the groundwater. Therefore, the biodegradation and adsorption properties of soluble polymers contained in PA are determined in this study. The soluble PA is highly polydisperse, and the fraction tested has a weight-average molecular-weight of 16,700 and a range extending from 10(3) to 10(5). Sand-column tracer tests show that about 1% of the polyacrylate is unadsorbed, but the remainder has a retardation factor that averages at least 58. Biodegradation kinetics are determined in completely mixed biofilm reactors having a methanogenic consortium grown on glucose. The polyacrylate fraction, as well as glucose and acrylate, are removed and mineralized to CO2. The Monod parameters for the polyacrylate are: maximum specific rate of substrate utilization = 0.0016 gC/g biomass-day, and half-maximum-rate concentration = 0.79 gC/m3. Although these kinetics are much slower than for glucose and acrylate, significant degradation and mineralization are observed.

Acrylic Resins↗
PubMedDate not supplied

Leptin and the regulation of food intake and the neuroendocrine axis in sheep.

1. Leptin is secreted by fat and acts on the brain. 2. Central infusion of leptin reduces food intake but does not alter endocrine secretions in normally fed sheep. 3. Leptin treatment can correct for altered hormonal secretion in fasted animals. 4. Alterations in bodyweight (leptin status) affect the expression of a number of genes in the hypothalamus that are involved in the regulation of food intake and neuroendocrine function. 5. Leptin receptors are found in both the hypothalamus and pituitary and direct action of leptin can be demonstrated on the somatotrophs in the pituitary.

Animals↗
PubMedDate not supplied

Polymicrobial infective endocarditis in the 1980s.

Clinical experience over the past decade suggests that the number of cases of polymicrobial infective endocarditis has greatly increased. We found 101 reports of cases of polymicrobial endocardial infection in a review of the English-language literature published in the 1980s. The mean patient age, 36.5 years, reflected a relatively young population, with men outnumbering women almost 2:1. Seventy-one patients were intravenous drug users; only three described recent invasive medical procedures. More than one-half of the patients had infections of the tricuspid valve, and 31 patients developed septic pulmonary emboli. The mean age of patients who died was significantly (P = .004) greater than that of those who survived. In comparison with patients who were infected with three or more organisms, those who were infected with two pathogens were almost twice (38.3% vs. 20.8%) as likely to die of their infections. These differences in mortality reflected the relative paucity of endocardial infections involving the left heart in patients with polymicrobial infections caused by three or more organisms (compared with those infected with two pathogens, P = .0032) and the variability in virulence among infecting agents.

Adult↗
PubMedDate not supplied

Nursing services administration in Norway.

Despite the importance of nurse administrators to a nation's hospitals and health service, there are few systematic studies analyzing the environmental context of nursing administration and how nurses function to improve the quality of care, control costs and maintain morale. To rectify this situation--which is as true for Norway as for most nations of the world--an in-depth study was conducted of chief nurses in Norwegian hospitals. The aim was to improve understanding of 1) what nursing administration is like, 2) the demands made of nurse administrators in a variety of organizational and geographical contexts, and 3) the skills that are needed to be successful. Below, a report of the study.

Cost Control↗