Search PubMed⌕ Search

Biomedical subjects

B Hayes

Publications and source records attributed to B Hayes.

At least 55 records · Page 3Linked to original sources

Diabetic autonomic dysfunction, blood pressure, and sleep.

We measured serially the blood pressure of 7 normal controls and 11 Type I insulin-dependent and 6 Type II non-insulin-dependent diabetic patients during sleep. All subjects underwent 2 or 3 nights of monitoring during which blood pressure was measured with an arteriosonde, a Doppler-type system with a cuff that automatically inflates every 15 minutes. All 7 normal controls, 3 of 11 Type I, and all 6 Type II diabetic patients had normal results from bedside tests of autonomic function. The Type I patients had abnormal systolic blood pressure measurements throughout the night. Unlike normal controls and Type II diabetics, their blood pressure did not rise progressively in the early morning hours. During rapid eye movement (REM) sleep, their blood pressure measurements were significantly higher and lower than values measured during non-REM sleep, in sharp contrast to those in the other two groups, whose REM sleep-related blood pressure values were slightly above the preceding non-REM sleep measurements.

Adult↗

An accurate method of measuring medical humidifier output.

A low-cost capacitance hygrometer capable of measuring steady-state and some transient changes in the output of medical humidifiers is introduced and evaluated. The method of operation is presented in detail, as is a comparison with the widely used gravimetric standard. The hygrometer produces results within 7% of those given by the gravimetric method when using units of percentage relative humidity (which give the widest discrepancies). This is shown to be an acceptable figure for the proposed application. Problems encountered when converting units of humidity are discussed in detail and methods of conversion explained.

Humans↗

Effectiveness of a sleep disorders center: a 9-month follow-up.

To assess the usefulness of a sleep disorders center the authors sent follow-up questionnaires to patients and referring physicians 9 months after each diagnostic evaluation. Findings suggest that sleep disorders centers provide a useful diagnostic service, especially for patients suffering from excessive daytime sleepiness. This problem usually has a medical etiology, and sleep laboratory evaluations seemed crucial for about two-thirds of all such patients. Insomnia was more likely to involve behavioral/psychological factors; about 30% of the patients with long-term, serious insomnia seemed to benefit markedly from the sleep center evaluation.

Disorders of Excessive Somnolence↗

An equipment logging system.

The application of Strafoplan logging to equipment used in the Intensive Care Unit is described and discussed.

Equipment and Supplies, Hospital↗

Streptococcal nucleases. II. Characterization of DNAse D.

Preparations of streptococcal DNAse D with high specific activity and free of other streptococcal nucleases have been obtained by zone electrophoresis and column chromatography. Antisera prepared by injecting rabbits with such preparations specifically neutralize the activity of this enzyme. As with DNAse B, preparations of DNAse D regularly exhibit ribonuclease activity. For both B and D enzymes, the order of substrate preference is thymus DNA, yeast RNA, bacterial RNA; but the specific activity of the D enzyme is higher than that of the B enzyme with respect to thymus DNA and lower with respect to bacterial RNA. Both the deoxyribonuclease and the ribonuclease activities exhibited by preparations of both enzymes are inhibited by bacterial RNA, but approximately 100-fold greater concentrations of bacterial RNA are required to achieve inhibition of the deoxyribonuclease activity of the D enzyme equivalent to the inhibition of the B enzyme. The deoxyribonuclease activity of the D enzyme is also inhibited by yeast RNA, but even larger amounts are required. These observations indicate that the D enzyme is immunologically distinct from the other streptococcal nucleases and that it differs quantitatively from the B enzyme with respect to relative specific activities on different substrates and behavior in the presence of the bacterial ribonucleic acid inhibitor.

Citrates↗