Pathology of the liver in early syphilis.
Explore the source record for details and available documents.
Humans↗
Biomedical subjects
B Hanchard
Publications and source records attributed to B Hanchard.
Cancer of the breast. A ten-year review at the University Hospital of the West Indies.
Explore the source record for details and available documents.
Adolescent↗
Primary hyperparathyroidism at the U.H.W.I.
Explore the source record for details and available documents.
Adolescent↗
Sinus histiocytosis with massive lymphadenopathy: clinico-pathological features of four cases.
Explore the source record for details and available documents.
Adolescent↗
Clonal evolution in two patients with autoimmune disease and lymphoreticular neoplasia.
Two cases are described, one with proven lymphosarcoma and doubtful autoimmune disease, and the second with the reverse situation, in which circulating abnormal mononuclear cells showed PHA responsiveness and an abnormal chromosomal constitution (clonal evolution). These findings are discussed in the light of previous cytogenetic studies of lymphoreticular neoplasia and autoimmune disease and the relationship between these two conditions.
Adult↗
Childhood infective dermatitis evolving into adult T-cell leukaemia after 17 years.
Explore the source record for details and available documents.
Child↗
Gastrology: the use of culinary terms in medicine.
Explore the source record for details and available documents.
Animals↗
Cervical intraepithelial neoplasia is not associated with elevated serum neopterin levels.
Neopterin, a marker of cellular immune activation, was elevated in patients who had cervical cancer in previous studies. To examine neopterin in the presence of precursors to cervical cancer (i.e., cervical intraepithelial neoplasia) we measured serum levels in 185 colposcopy patients in Jamaica, a country with high cervical cancer incidence, and in 72 age-matched Jamaican women selected from a large population-based sample. We also measured serum levels of beta-2-microglobulin, another commonly used marker of immune activation. Neopterin and beta-2-microglobulin levels were not elevated in colposcopy patients; neither were they related to severity of cervical neoplasia. In multivariable analysis, neither adjustments for detection of cervical human papillomavirus DNA by PCR nor detection of antibodies to human T-cell lymphotropic virus type I (a retrovirus endemic to Jamaica) altered our findings. The absence of a serologically detectable increase in cellular immune activation linked to cervical intraepithelial neoplasia suggests that the immunological response to cervical intraepithelial neoplasia does not involve substantial systemic cellular immune activation.
Biomarkers, Tumor↗