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Biomedical subjects

B Haldar

Publications and source records attributed to B Haldar.

At least 19 recordsLinked to original sources
PubMed1985

Studies on vitiligo. I. Epidemiological profile in Calcutta, India.

An epidemiological profile of vitiligo in Calcutta is presented. Prevalence data were gathered from 15,685 individuals drawn from the general population; pedigree data were collected through 293 vitiligo patients. The overall prevalence of vitiligo is about 5 per 1,000 individuals. There are no significant sex or age differences in prevalence rates. About a 4.5-fold increase in prevalence is observed among close biological relatives of affected individuals. There is, however, no clearcut correspondence between relative risks and kinship coefficients. There are no significant differences in the frequencies of various types of vitiligo between probands with and without positive family history. The overall mean and modal ages of onset are about 22 years and 15 years, respectively. The mean ages among males (24.8 years) and females (19.3 years) are significantly different.

Adolescent↗
PubMed1985

Studies on vitiligo. II. Familial aggregation and genetics.

Data on 298 pedigrees, each collected through an affected proband, have been analyzed to study familial aggregation and genetics of vitiligo. The extent of familial aggregation is statistically significant at the 5% level. The disease does not appear to be inherited in a simple dominant or recessive fashion. The heritability of liability to the disease is 46% +/- 4.82%. Neither common family environment nor a major locus with additional sources (environmental and/or polygenic) can be excluded as a cause of familial aggregation. Association of the disease with six polymorphic genetic marker loci have been studied. Significant associations with ACP1 and RH loci have been found. This and earlier studies indicate that the disease is associated with genetic loci on different chromosomes, which points to a polygenic nature of the disease.

Acid Phosphatase↗
PubMed1983

Foot drop, mimicking neuritic leprosy induced by a Baker's cyst.

A Baker's cyst of the left knee joint induced foot drop insidiously in a male, Hindu, aged 25 years. On clinical suspicion, that this malady was caused by neuritic type of leprosy, he was administered antileprosy drugs for 6 months without any benefit. On exploration a globular cystic mass, containing gelatinous fluid, was seen to be pressing over the left lateral popliteal nerve. Following removal of this mass, which on histology confirmed to be a Baker's cyst, foot drop and associated motor power impairment disappeared. This case thus highlights the importance of an early exploration and histological diagnosis of a suspected case of neuritic leprosy inducing foot drop and progressively deteriorating, inspite of regular antileprosy therapy.

Adult↗
PubMed1983

Leiomyoma cutis.

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Adolescent↗
PubMed1976

The urticarias.

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Adult↗