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Biomedical subjects

B H Goldstein

Publications and source records attributed to B H Goldstein.

32 records · Page 2Linked to original sources
PubMed1975

Histocompatibility and tooth transplantation in the rabbit.

Allogeneic orthotopic tooth transplants in the rabbit appear to stimulate transplantation immunity reactions comparable to those encountered with the transplantation of other organs. Intact untreated teeth were shown to be as quantitatively immunogenic as skin grafts between unrelated animals. Histocompatibility matching of donor and recipient and removal of pulpal tissues were demonstrated to be effective means of ameliorating the immune response to allogeneic orthotopic tooth transplants in the rabbit.

Animals↗
PubMed1975

Acute (toxic) epidermal necrolysis. Report of a case.

A case of acute (toxic) epidermal necrolysis is reported in the dental literature for the first time. This severe, life-threatening mucocutaneous syndrome resembles severely scalded skin. Sloughing vesiculobullous oral lesions are a frequent component. Staphylococcus aureus and drug reactions may cause separate entities presenting clinically as acute epidermal necrolysis. This case of drug-induced epidermal necrolysis ina child was successfully treated with methicillin and hydrocortisone.

Child, Preschool↗
PubMed1968

DAU at Penn.

Explore the source record for details and available documents.

Dental Assistants↗
PubMedDate not supplied

Spontaneous bacterial peritonitis following treatment for cervical carcinoma.

Spontaneous bacterial peritonitis (SBP) is an acute bacterial infection usually associated with ascites and cirrhosis or is a complication of peritoneal dialysis. There are very few case reports of cancer patients who developed this disease. Furthermore, there have been no published case reports of successfully treated gynecological cancer patients who later developed SBP. We present a case involving a 41-year-old woman who was treated for cervical carcinoma in 1992. She underwent radical surgery and adjuvant chemoradiation therapy. Two years later, the patient presented with streptococcal group B cellulitis associated with left leg lymphedema. She recovered following antibiotic treatment but had recurrent episodes of streptococcal cellulitis in her leg over the past 10 years. In 2003, the patient was admitted to the hospital because of sepsis, acute renal failure, and SBP. She was treated and recovered following treatment. SBP is usually associated with cirrhosis. Although SBP is rarely seen in successfully treated gynecological cancer patients, oncologists should be aware of this clinical entity. Timely treatment is essential to maximize chances of survival.

Adult↗
PubMedDate not supplied

Surgery alone or surgery with a combination radiation or chemoradiation for management of patients with bulky-stage IB2 cervical carcinoma.

The management of stage IB2 cervical carcinoma remains controversial. This retrospective review evaluates 47 IB2 cervical carcinoma patients treated with surgery alone (S), surgery plus postoperative radiotherapy (SR), or surgery plus postoperative chemoradiation (SRC). Median progression-free interval (PFI) was 70.3 months for the SR group (n= 21), 73.3 months for the SRC group (n= 15), and 33.5 months for the S group (n= 11). The survival rate was 76% for the SR group, 87% for the SRC group, and 55% for the S group. Overall 5-year survival rate for the three groups was 75%. Median follow-up for the patient population was 61.3 months. The number of the patient and the nonrandomized nature of this study preclude any definitive conclusions, but interestingly, the SRC and SR groups exhibited a substantially better PFI and overall survival compared to the S group. Selection bias does not appear to be a factor since patients in SR or SRC group were at greater risk for recurrence (eg, higher incidence of deep stromal invasion, parametrial involvement) than patients in the S group; yet, they still experienced superior PFI and overall survival. Further studies comparing postoperative irradiation and chemoradiation with these patients in a randomized phase 3 trial may be warranted.

Adenocarcinoma↗
PubMedDate not supplied

Neuropsychological treatment of dyslexia in the classroom setting.

The purpose of this study was to validate Bakker's (1990, 1992) clinical neuropsychological balance model of dyslexia when implemented in a traditional general education classroom environment. The sample included 45 middle school, right-handed boys and girls (mean age = 12.78) with L-type dyslexia (excessively fast readers who make substantive reading errors), P-type dyslexia (displaying accurate but slow and laborious reading), and M-type dyslexia (readers who commit a combination of L-type and P-type dyslexia errors). The experimental groups (L and P type dyslexia) were presented with hemisphere specific stimulation (HSS) and hemispheric alluding stimuli (HAS). HSS involves the presentation of words into the right visual field (RVF) or the left visual field (LVF) or through tactile exercises with the right or left hand. HAS is achieved by constructing semantically and phonetically challenging letters and words. The children with M-type dyslexia served as a control group and received traditional decoding and comprehension exercises. The readers were exposed to a specific treatment model for 16 weeks, depending on their reading accuracy and comprehension. Statistical analyses indicated that, although there were no significant changes in word recognition for the dyslexia subtypes, the readers with L-type, P-type, and M-type dyslexia exhibited significant improvement in reading accuracy and comprehension as assessed by results from pretest to posttest. These results suggest that Bakker's clinical neuropsychological intervention can be effectively applied to the general education setting as well.

Adolescent↗
PubMedDate not supplied

Unconventional dentistry: Part II. Practitioners and patients.

This is the second in a series of five articles providing a contemporary overview and introduction to unconventional dentistry (UD) and its correlation with unconventional medicine (UM). Dentists may provide unconventional services and use or prescribe unconventional products because of personal beliefs, boredom with conventional practice, lack of understanding of the scientific process or financial motivation. To promote these UD practices, unrecognized credentials and self-proclaimed specialties are advertised. Characteristics of users of unconventional practices are varied; however, UD users are more often female and highly educated. UD practitioners and users generally appear to be analogous to UM practitioners and users. Some UD treatments are more invasive or more costly than conventional dentistry.

Complementary Therapies↗