Proceedings: myoelectrical activity in the rectosigmoid in man.
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Biomedical subjects
Publications and source records attributed to B H Brown.
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Electrical and motor activities of the terminal ileum have been recorded in 25 patients with a permanent ileostomy. Records made within a week of formation of the ileostomy show an increased motor activity which is significantly reduced after four weeks. Intravenous infusion of gastrin, 1 mug/kg-hr, was accompanied by a significant increase in action potentials and in the percentage motility. Conversely, secretin 1 unit/kg-hr was associated with a decrease in action potentials and in percentage motor activity.
An automatic method using an analogue analyser is described for obtaining an index which is based on the mean phase duration of an EMG signal. This method gives similar values for motor unit action potential duration to an alternative digital method of analysis based on the distribution of time intervals between zero crossings of the EMG signal. The analysis has been found to give good discrimination of normal and myopathic EMG signals.
An automated method of quantitating small electromyographic changes, based on the ratio of action potential duration to the number of phases per potential, was applied to carriers of X-linked Duchenne type muscular dystrophy. The ratio was found to be significantly raised in a proportion of these cases.
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The pacesetter potential of the gastric antrum and proximal duodenum has been recorded in man by electrodes placed under the serosal coat of the gut. The typical 3 cycle/min of the stomach was found to be conducted across the pylorus into the first part of the duodenum at a rate (2 cm/sec) about four times as fast as its conduction in the more proximal antrum (0.5 cm/sec). A 3 cycle/min pacesetter potential could be detected as far distally in the duodenum as 10 cm from the pylorus.
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