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Biomedical subjects

B Guerrier

Publications and source records attributed to B Guerrier.

84 records · Page 5Linked to original sources
PubMedDate not supplied

[Inflammation and laryngitis].

1. DISTINCT ENTITIES: Unlike inflammation or the middle ear or nasal or sinus cavities, there is no direct link between acute and chronic inflammation of the larynx. Chronic laryngitis is a distinct nosological entity. Patients with recurrent allergic laryngitis do not necessarily develop chronic laryngitis as is observed in patients with nasal allergy. 2. RESEARCH: There is no research data on infections of the larynx comparable to that available for the middle ear or the nasal cavities. This is probably related to the difficulty of accessing the laryngeal mucosa and the risks related with this condition. 3. CLINICAL TRIALS: While fundamental research remains to be conducted, their is a large body of clinical trials on the topic, although one must be prudent concerning the terms used. 4. NOSOLOGOGY: In French the term "croup" designates diphtheritic croup and must be distinguished from the more general term used in English. Clinical trials must be interpreted with caution since it is often difficult to ascertain which type of laryngitis is concerned. 5. GRAVITY SCORES: Widely used in the English literature, gravity scores are not generally used in French pediatric ENT units and have no real equivalent in French. 6. DYSPHONIA AND DYSPNEA: Dysphonia is the leading sign of chronic laryngitis. Dyspnea is the leading sign of acute laryngitis. Dyspnea is more frequent in children and is related to disease severity. 7. BACTERIA AND VIRUSES: Epiglottitis (supraglottic laryngitis) is related to bacterial infections while subglottic laryngitis is related to viral infections requiring antibiotics in combination with corticosteroids. 8. H. INFLUENZAE: The most common causal agent of epiglottitis, type B Haemophilus influenzae, is not the only culprit. 9. ADULTS: Epiglottitis can also occur in adults where it is as severe as in children. 10. SYSTEMIC CORTICOSTEROIDS: Emergency administration of systemic and inhaled glucocorticoids in the hospital setting is the basic treatment for glotto-subglottic laryngitis. Dosage must be high, more than 0.3 mg/kg dexamethasone for 48 hours, followed by oral corticosteroids.

Administration, Oral↗
PubMedDate not supplied

[MRI/CT x-ray comparison in the pre-operative evaluation of cancer of the larynx. Apropos of 46 cases].

The authors present the comparative value of CT scan and MRI in the pre-operative staging of 46 laryngeal carcinomas. The "in depth" evaluation conducts the choice of conservative surgery. CT scan is the reference but MRI reveals itself as effective and even more in certain cases. The spontaneous contrast gradient for soft tissues of the MR imaging explains this effectiveness of the method. The paraglottic space and the subglottic extension are more easily studied by MRI. If the expansion of the MRI Unities allows this indication of the pre-operative staging of laryngeal carcinomas is an excellent one.

Humans↗
PubMedDate not supplied

[Cervical paragangliomas. Results apropos of a series of 33 patients].

During the period 1971-1993, 33 patients were treated for cervical chemodectomas, 41 tumors were diagnosed. Seven patients had multicentric tumors. All patients expect one with bilateral carotid tumor were treated surgically. A carotid resection was performed in 4 patients. Six patients were given radiation therapy: five patient after surgery and one treated by irradiation alone. During the follow-up period one patient died of bone metastasis 6 year after a partial surgery and radiation therapy, and one had local recurrence treated with irradiation. The surgical management is the major treatment of these tumors, it revealed no postoperative cerebrovascular accident and limited complications secondary to unavoidable nerves sacrifice. Radiation therapy is performed only on particular cases: surgery contra-indications and nonradical resection.

Adult↗