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Biomedical subjects

B Guerrier

Publications and source records attributed to B Guerrier.

At least 55 records · Page 3Linked to original sources

Assessment of laryngeal cancer: CT scan versus endoscopy.

In order to assess the value of the systematic use of CT scan in the workup for laryngeal cancer, a retrospective study was conducted on 66 consecutive previously untreated cases of laryngeal cancer. Endoscopic and CT scan findings were systematically compared. The areas of particular difficulty in CT scan assessment are described. CT scan alone understaged laryngeal cancers in 10.6% of cases, all of them being superficial spreading tumors within the larynx or in the juxtalaryngeal areas. CT scan worsened the staging in 22.7% of cases, all of them being deep invasions overlooked by endoscopy. CT was most useful in lesions initially classified as T2 and T3, which included all those reclassified by CT. None of the T1 lesions was upgraded after CT, and systematic use of CT for this stage is not warranted. CT scan workup changed the therapeutic attitude in 10 of the 66 patients (15.1%), causing a switch to conservative surgery in seven patients and total laryngectomy with radiotherapy for the three others. CT was also valuable in choosing the most suitable technique for conservation surgery.

Carcinoma, Squamous Cell↗

[Pharyngo-esophageal risk of surgery of the cervical spine using an anterior approach].

The authors report six cases of pharyngo-oesophageal damage associated with fractures of the cervical spine treated by osteo-synthesis via the anterior route. These complications, not previously described, may have life threatening (especially mediastinitis) and functional consequences. They discuss the relative responsibility of: the initial trauma, which should be better defined by an initial endoscopic assessment. the surgical approach, the principles of which and its dangers and preventive aspects are discussed, early or late fixation failure justifying careful surveillance of the osteosynthesis material and in certain cases its systematic removal.

Adult↗

[Partial laryngectomies in the old patient (more than 70 years of age). Apropos of 25 cases].

Over a six-year period, from 1981 to 1985, the authors operated on 25 patient aged 70 years or more for infiltrative cancer of the larynx. Indications for surgery are identical to those for a younger patient. Contraindications of a general nature are scrupulously observed and the exploration of respiratory function is one of the key complementary examinations. Survival figures are very encouraging, as the increase in intercurrent mortality seen in this age group is balanced by the lesser degree of aggressivity of the initial tumour and of its ganglionic metastases.

Aged↗

[Our experience in reconstructive surgery in glottic cancers].

A retrospective study was carried out in 58 patients operated between 1978 and 1983 for cancer of larynx of glottic origin and mainly T1 and T2. Functional results were always of good quality, and the recurrence rate significantly lowered by the use of the Majer-Piquet or C.H.E.P. procedure when compared with results after thyroidectomy. A simplified technique is proposed.

Adult↗

Cancer of the piriform sinus: treatment by radiation therapy alone and with surgery.

To ascertain the optimal treatment for carcinoma of the piriform sinus, the authors determined survival rates and local and regional tumor growth for two groups of patients: those treated by radiation therapy alone (n = 209) and those treated by radiation therapy combined with surgery (n = 154). The two groups were similar with respect to the characteristics of primary tumor stage and degree of nodal involvement. The overall 3-year and 5-year actuarial survival rates were 19.2% and 15.5%, respectively. For 5-year actuarial survival, there was no significant difference between patients with T1 and T2 tumors, but there was a significant difference between patients with T1 + T2 tumors versus those with T3 tumor. There was no significant difference in 3- and 5-year survival between patients with N0 and N1 nodal involvement and those with N1 and N2 involvement, but there was a significant difference between patients with N0 versus those with N3 involvement. The 5-year actuarial survival rate is significantly better for patients who underwent surgery followed by radiation therapy than for those who received only radiation therapy. However, for patients with early-stage (T1 and T2) tumors, radiation therapy alone controls local tumor growth as well as the combination of surgery and radiation therapy does. For each treatment group, the causes of death and patterns of failure were studied and compared with investigations to date.

Actuarial Analysis↗

[Congenital vascular tumor of the larynx: cellular hemangioma].

A 9 year old child was operated upon for a very vascular tumor of the right piriform sinus, signs of which had been present at birth. Histopathologic and ultrastructural examinations showed the lesion to be composed of both endothelial and pericytic elements, suggesting the diagnosis of a cellular hemangioma. This tumoral variety, particularly rare in the larynx, has been distinguished from the group of hemangiopericytomas described by Stout and Murray, not only by its usual congenital character and course but also by its specific structure.

Child↗

[Muco-epidermoid tumors and acinic cell tumors of the parotid gland].

Mucoepidermoid and acini cel carcinoma of the salivary glands are relatively rare and have a tendency to recur locally and sometimes metastasize to lymph nodes and at a distance. Such an evolution is difficult to predict even if one uses anatomo-pathological criteria, which explains the uncertain prognostic of these neoplasms and the difficulty encountered in establishing their therapy. Seven cases of mucoepidermoid carcinoma and five cases of acinic cell carcinoma are reported with statistical, clinical, and anatomo-pathological data. The evolution of these tumors are studied according to the therapy used, which leads us to establish a therapeutic protocol.

Adolescent↗

[Congenital laryngeal membrane. Apropos of 2 case reports].

Two observations of congenital partial atresia of the larynx are studied. They thus illustrate the diagnostic and therapeutic difficulties with which the clinician is faced. A rare malformation (one out of a million births), sometimes in the same family (3,6%) the congenital partial atresia of the larynx presents a wide anatomical variety and consecutively a wide clinical variety. Diagnosis is always confirmed by endoscopy. Treatment uses either continuous gauging of the larynx (or discontinuous) with tracheotomy or surgery. It is at present impossible to define formally any therapeutic; nevertheless exhaustive study of the literature, and the progress of micro-surgery (with the contribution of the laser) should allow the therapy to be specified on the basis of the anatomy, the age and the degree to which the malformation is tolerated.

Abnormalities, Multiple↗