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Biomedical subjects

B Gregg

Publications and source records attributed to B Gregg.

10 recordsLinked to original sources
PubMed2005

An investigation of the impact of the Force Sensing Array pressure mapping system on the clinical judgement of occupational therapists.

OBJECTIVES: To examine the impact of pressure mapping technology on the clinical decisions of occupational therapists and to examine the role of the Braden Scale in assisting with the selection of pressure-reducing cushions. DESIGN: Case studies. SETTING: Community. SUBJECTS: Forty clients. INTERVENTIONS: Clients were pressure mapped on their current seating surface and on four pre-selected cushions by the principal researcher. An occupational therapist completed the Braden Scale and a decision tree to assist in recommending a suitable pressure-reducing cushion. MAIN OUTCOME MEASURES: Interface pressure maps, Braden Scale, and the cushion recommended, using a decision tree to guide clinical judgement. RESULTS: Thirty per cent (12) of the 40 cushions recommended were changed when the pressure maps from the Force Sensing Array (FSA) system were viewed. In 70% (26) of cases, the maps supported the cushion recommended. In 25% (10) of the cases, the maps showed that the client's current seating surface was unsuitable. After viewing the pressure maps, a surface other than the client's current surface was recommended in 47% (19) of the cases. There was a lack of agreement between the risk level of the clients as identified by the Braden Scale score, and the risk level of the clients as identified by the occupational therapist using a decision tree and the FSA maps. CONCLUSION: Pressure mapping technology has a positive impact on clinical decisions regarding the provision of pressure-reducing cushions. Future research should examine the predictive validity of this technology. The Braden Scale may underpredict the risk level of the clients.

Activities of Daily Living↗
PubMed1996

Paradigm for SCI nurse competency on adult-geriatric SCI rehabilitation unit.

This article is based upon an SCI Model Project, funded by the American Association of Spinal Cord Injury Nurses (AASCIN). The purpose of this project was to develop a model to validate theoretical and practical knowledge of Registered Nurses and Licensed Practical Nurses/Licensed Vocational Nurses in an SCI rehabilitation setting. The investigators were direct care providers in a 68 bed SCI rehabilitation service at the James A. Haley Veterans Hospital in Tampa, Florida. The theoretical framework was based upon three aspects: Competency Validation, Theoretical Knowledge, and Practical Knowledge. Competency Validation was directed towards incorporating the elements of assessment, maintenance, demonstration, and improvement of competencies on an ongoing basis. Theoretical knowledge encompassed the cognitive and psychomotor aspects of SCI nursing, and Practical Knowledge highlighted the application of principles of caregiving. Two instruments were developed to harmonize theoretical and practical dimensions for competency validation: SCI Knowledge/Skill Appraisal (SKA) and Expertise in SCI Nursing Practice (ESNP). The purpose of this project was to design a model for validating theoretical and practical knowledge of Registered Nurses (RN's) and Licensed Practical Nurses/Licensed Vocational Nurses (LPN/LVN's) in an SCI rehabilitation setting. The investigators were direct care Licensed Practical Nurses/Licensed Vocational Nurses (LPN/LVN's) in an SCI rehabilitation setting. The investigators were direct care providers in a 68 bed spinal cord injury (SCI) rehabilitation service at the James A. Haley Veterans Hospital in Tampa, Florida.

Adult↗
PubMed1989

Expert systems survey on biodegradation of xenobiotic chemicals.

To determine the feasibility of developing an expert system for biodegradability assessment, a survey was conducted in which biodegradation experts were asked to estimate rates and products of degradation for 50 chemicals. These chemicals, which varied widely in structure, were considered representative of the spectrum of premanufacture notice chemicals subject to EPA review under the Toxic Substances Control Act. There was substantial agreement among the 22 experts on both sites of initial attack and rates of degradation. The approximate order in which various groups were viewed as contributing to aerobic biodegradability is as follows: ester, amide, anhydride greater than hydroxyl greater than carboxyl, epoxide, site of unsaturation greater than benzene ring, methyl, methylene. Hydrolyzable groups, azo bonds, halogens, and nitro groups were preferred sites of anaerobic attack. Among the negative influences on aerobic biodegradability were molecular mass, branching, halogenation, and nitrogen heterocycles. Results also indicate that estimates of removal by biodegradation in aerobic wastewater treatment and time for aerobic ultimate and primary degradation were well correlated, and that the predictive value of such correlations could be improved using correction factors for certain classes of chemicals. The results lend support to existing rules of thumb, but also offer additional insight that will prove useful in designing a prototype system.

Biodegradation, Environmental↗
PubMed1986

Type A behavior pattern and the judgment of control.

We investigated the control judgments of Type A and B actors and observers after five tasks in which actual response-outcome contingency and success were varied systematically. Results indicated that, overall, actors provided higher control judgments than did observers, and both actual contingency and success influenced judged control. Type A and B actors did not differ in their self-perceptions of control but observers judged the Type A actors to have exerted more control than the Type B actors, primarily on positive contingency tasks. These findings suggest that Type As, because of their more active, dynamic style, may be credited by observers with more control or competence than is warranted. By contrast, the more relaxed style of the Type B may lead to lower than warranted evaluations of control or competence. Lastly, Type As were found to learn the contingencies better than Type Bs with important implications for the actual exercise of control.

Achievement↗
PubMed1986

Brain stem reticular formation neuronal correlates of stimulus significance and behavior during discriminative avoidance conditioning in rabbits.

Multiple-unit activity in the reticular formation of the midbrain and pons was recorded in rabbits during discriminative conditioning of locomotor (wheel-running) avoidance behavior. The conditional stimuli (CS+ and CS-) were pure tones of different auditory frequency, and the unconditional stimulus (US) was a constant-current footshock (1.5-2.5 mA) delivered through the grid floor of the wheel. The pontine, but not the midbrain, sites manifested development during behavioral acquisition, of brief-latency (10-40-ms) discriminative neuronal discharges (i.e., greater discharges to the CS+ than to the CS-). The greatest magnitude of the discriminative discharges in the rostral pontine loci occurred in the first conditioning session. The discriminative response in the caudal loci developed more slowly, and it persisted to the criterial stage of training. Both rostral and caudal pontine loci, during the interval from CS onset to US onset, manifested a progressive build-up of neuronal firing in anticipation of the behavioral response. The occurrence in the rostral and caudal pontine areas, respectively, of early- and late-developing discriminative discharges is analogous to effects observed in past studies in the limbic mesocortical and thalamic systems. These findings provide a basis for establishing the possible functional relatedness or independence of these analogous effects.

Animals↗
PubMed1978

Ingestional aversion learning in preweanling rats.

Ingestional aversions were conditioned in 12- and 15-day-old rats by infusing a .5% solution of saccharin into the oral cavity and following this oral infusion by the injection of lithium chloride. At both ages, subjects for which the saccharin exposure was followed by lithium injection within 2-3 min drank less when the saccharin solution was again presented by oral infusion 12 hr later; such suppressions of intake were not observed in subjects that previously received the saccharin and lithium in an unpaired fashion (Experiments 1 and 3). Ingestional aversions were also learned by 12-day-olds when a 30-min interval was introduced between saccharin exposure and lithium toxicosis but not when toxicosis was delayed by 120 min (Experiment 2). In contrast, 15-day-olds learned aversions with both the 30- and 120-min-delay intervals (Experiment 3). Despite the absence of long-delay learning in 12 day olds, ingestional aversions conditioned at 12 days of age were retained for 2 wk (Experiment 4). These results provide further evidence of the associative abilities of neonatal rats and illustrate a developmental aspect of long-delay learning.

Age Factors↗
PubMed1977

Simplification of B-cell antisera of the Merrit system with platelets and lymphoblastoid cell lines.

Human sera with anti-HLA and anti-Merrit B-cell reactivities were absorbed with different volumes of a pool of packed outdated human platelets obtained from 237 donors. After absorption, each serum was tested against a panel of CLL cells and normal unfractionated peripheral blood lymphocytes that had given positive reactions with the same serum prior to absorption. The optimal platelet volume for complete absorption of anti-HLA and full preservation of anti-Merrit B-cell activities in these sera was found to be 1/10 to 1/5 of the volume of serum. Higher volumes of packed platelets, especially over 1/1, in most instances reduced anti-B-cell activity "nonspecifically." Among the platelet absorbed sera, those showing no HLA and strong anti-Merrit B-cell cytotoxicity were used for cross-absorption studies with cultured human lymphoid cell lines. Multi-specific anti-Merrit sera could be simplified by this method. Cultured lymphoblastoid cell lines represent a valuable resource, since large volumes of cells may be needed for absorption and simplification of human sera containing allogeneic B-lymphocyte antibodies.

B-Lymphocytes↗