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Biomedical subjects

B Green

Publications and source records attributed to B Green.

At least 163 records · Page 9Linked to original sources
PubMed1982

Ploidy and progesterone-receptor distribution in flow-sorted deciduomal nuclei.

Nuclei from rat uterine deciduomata were analysed and sorted into different ploidy classes in a fluorescence-activated cell sorter. The highest proportion of 8 n and 16 n nuclei was observed on days 6-7 after decidualization. At this time the progesterone receptor content per unit DNA of the octaploid nuclei was less than half that of the diploid nuclei.

Animals↗
PubMed1982

Comprehensive evaluation of electrocardiographic methods for detection of myocardial infarction.

In two groups of patients the detection of myocardial infarction (MI) by analysis of four different electrocardiographic methods was evaluated. The various methods included the conventional 12 lead ECG (CV-ECG), the 12 lead ECG derived from Frank XYZ lead system signals (D-ECG), the polarcardiogram (PCG) and the vectorcardiogram (VCG). An invasive group consisted of 137 patients who had undergone cardiac catheterization. An MI was defined as a regional wall motion abnormality in the distribution of a coronary artery with at least 70% diameter reduction. The noninvasive group consisted of 116 patients in whom independent clinical information was limited to noninvasive assessments. In this group, Telemed Computer Systems' interpretation of the conventional (TC-ECG) and derived (TD-ECG) electrocardiogram was also available for comparison. An MI was defined in this group as either a compatible history with documented cardiac enzyme elevations, a resting defect on thallium scan, or a regional wall motion abnormality in a resting, radionuclide isotope ventriculogram. In this study the other methods of ECG evaluation demonstrated no advantage over the electrocardiographer's reading of the conventional ECG.

Adult↗
PubMed1982

Treadmill test responses to an early exercise program after myocardial infarction: a randomized study.

The effects of an exercise program started early after myocardial infraction and the added effects of an outpatient teaching-counseling program were studied. At random, 84 patients were allocated to a control group (A), 88 patients to an exercise group (B1) and 86 patients to an exercise and teaching-counseling group (B2). The same exercise program was prescribed for patients in groups B1 and B2 and was started about 4.5 days after myocardial infarction and continued for 3 months. The outpatient teaching-counseling program consisted of eight group sessions pertaining to risk factor reduction and psychosocial adjustment to myocardial infraction. A low-level treadmill test and an exercise test were performed at 3 months and the exercise test was repeated at 6 months. The clinical, hemodynamic and electrocardiographic responses to these tests were not different among the three groups. However, by the end of 3 months, patients in group B1 and B2 reported walking greater distances than patients in group A. The incidence of morbidity and mortality was not different between the groups. No deleterious or beneficial physiologic effects of an exercise program either by itself or combined with a teaching-counseling program were demonstrated. Routine medical care and our interventions were equally effective in permitting the spontaneous hemodynamics improvements after myocardial infraction. More than 3 months after myocardial infarction, the group as a whole manifested spontaneous recovery in the form of a significant decrease in resting heart rate (p less than 0.001) and a significant increase in systolic and diastolic blood pressure at rest and with submaximal exercise (p less than 0.001). No further improvements were observed between 3 and 6 months.

Blood Pressure↗
PubMed1982

Surviving stress.

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Adaptation, Psychological↗
PubMed1982

A few funny cells.

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Carcinoma in Situ↗
PubMed1981

In-hospital exercise after myocardial infarction does not improve treadmill performance.

Prolonged bed rest after myocardial infarction is thought to result in deconditioning, manifested by increased heart-rate and blood-pressure responses to exercise and decreased functional capacity. We studied the effects of early, supervised exercises in preventing deconditioning after acute myocardial infarction. Eighty-four patients were randomized to a control group and 174 to an exercise group. Enrollment in the exercise program occurred an average of 4.5 days after admission (range, one to nine). Discharge from the hospital occurred an average of 10.3 days after admission in the control group and 10.4 days in the exercise group. Most patients had a low-level treadmill test on the day before hospital discharge. There were no differences between the two groups in the clinical, hemodynamic, or electrocardiographic responses to the treadmill test. Incidences of complications and deaths (one death in each group) during hospitalization were not significantly different in the two groups, although six patients (3 per cent, all in the exercise group) required cardiac surgery--four because of recurrent chest pain and two because of rupture of heart muscle. Thus, we were unable to demonstrate any significant beneficial or deleterious effects of an early, in-hospital exercise program.

Aged↗
PubMed1981

Enzymes of galactose metabolism in livers of suckling and adult tammar wallabies (Macropus eugenii) and other marsupials.

The activities of galactokinase, hexose-1-phosphate uridylyl transferase and UDPglucose 4-epimerase in homogenates of livers of two adult and 20 suckling tammar wallabies aged from 6 to 50 weeks were investigated. The activities of all three enzymes were high until 24-30 weeks post partum, after which they declined to low levels. The activities of the three liver enzymes were high in pouch young of six other species of marsupial. Comparison of the activities of the three liver enzymes in suckling tammar wallabies with those in suckling rats showed no difference between the two species in regard to galactokinase and uridylyl transferase, but the UDPglucose 4-epimerase activity in tammar wallabies was approximately double than found in rats. This may be related to the high galactose content of tammar wallaby milk compared with rat milk. In suckling tammar wallabies, the liver had higher enzyme activities than other tissues studied. It is concluded that, contrary to the suggestion of Stephens et al. (1975), pouch young marsupials are not deficient in their ability to metabolize galactose.

Aging↗
PubMed1981

Characterization of a Nuclear Polyhedrosis Virus Isolated from Diseased Gonometa podocarpi (Lepidoptera:Lasiocampidae).

Gonometa podocarpi is an important pest of several species of pine in East Africa, and large numbers of trees in plantations in Kenya were partially or completely defoliated by the larval stage of this insect. After the infestation in the Mt. Elgon region, large numbers of dead and moribund larvae were found on the ground. Examination of extracts of these larvae demonstrated the presence of an occluded virus. Electron microscopy of purified sectioned polyhedra demonstrated the presence of virus particles containing from 1 to 12 nucleocapsids. Purification of virus particles from polyhedra was accomplished by using alkali solubilization and sucrose gradient centrifugation. Virus particles contained 15 proteins as determined by polyacrylamide gel electrophoresis. Detergent solubilization of the virus particles released polyhedra containing one major structural protein. Electron microscopy of purified virus particles and nucleocapsids demonstrated them to be similar in structure to previously recorded nuclear polyhedrosis viruses. The viral deoxyribonucleic acid was extracted and spread for electron microscopy and was determined to have a size of approximately 80 x 10 daltons.

Journal Article↗
PubMed1980

Nuclear progesterone and estradiol receptors in deciduomata induced in ovariectomised rats.

The levels of nuclear progesterone and estradiol receptors have been followed during the development and decline of deciduomata induced in the uteri of ovariectomised rats. There were broadly 2 phases of deciduomal growth, the first phase being associated with high estrogen nuclear receptor levels per unit DNA. Progesterone nuclear receptor levels did not greatly change (in relation to DNA content) during both phases of full deciduomal development but peak levels were observed on day 5 after decidualization. Alkaline phosphatase activity was maximal by day 3, before peak hormone receptor levels were reached in the nuclei.

Alkaline Phosphatase↗
PubMed1980

Ultrasonographic patterns of hepatic lymphoma.

The hepatic sonograms of 443 patients with lymphoma were reviewed. Of these patients, 357 had nonHodgkin lymphoma, while 86 had Hodgkin disease. Sonography was able to detect disease in 5.2% of the total patient population. Disease was found in 5.8% of Hodgkin patients and 5.0% of nonHodgkin patients. The various sonographic patterns of disease are described. Hypoechoic and diffuse disease were seen in both types of lymphoma, while target and echogenic lesions were only seen in nonHodgkin lymphoma.

Diagnosis, Differential↗
PubMed1980

Changes in milk composition during lactation in the tammar wallaby (Macropus eugenii).

Milk samples were obtained at regular intervals throughout lactation from tammar wallabies (M. eugenii). Total solids represented only 12% (w/w) of the milk at the commencement of lactation and gradually increased to about 40% at 36 weeks. Milk proteins represented 4% (w/w) of whole milk during the first 18 weeks of lactation, followed by a rapid increase to around 13% (w/w) at 36 weeks. Sodium and potassium concentrations were high in early samples of milk but declined to minimal values at 30 weeks. The milk was isosmotic to the plasma at all stages.

Animals↗