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Biomedical subjects

B Gray

Publications and source records attributed to B Gray.

At least 109 records · Page 6Linked to original sources
PubMed1981

Correlation of Doppler-derived high thigh pressure and intra-arterial pressure in the assessment of aorto-iliac occlusive disease.

Ninety-five lower extremities in 53 patients underwent iliofemoral arteriography, high thigh wide cuff Doppler pressure measurements and direct intra-arterial pressure measurements at the common femoral level to determine the accuracy of the high thigh Doppler technique in the evaluation of aorto-iliac occlusive disease using the intra-arterial pressure as the standard. Results showed the high thigh cuff Doppler technique to be 79 per cent sensitive, 56 per cent specific and 63 per cent accurate in the evaluation of haemodynamically significant aorto-iliac disease. There was a false negative rate of 13 per cent, but a false positive rate of 59 per cent. All false positive tests were shown to be secondary to superficial femoral artery disease. These results indicate that a normal high thigh wide cuff Doppler pressure is generally reliable in ruling out haemodynamically significant aorto-iliac, occlusive disease at rest. An abnormal result, however, does not differentiate between aorto-iliac and superficial femoral artery disease.

Aorta, Abdominal↗
PubMed1980

Local leukocyte mobilization in irradiated or cyclophosphamide-treated rats.

Sprague-Dawley rats made neutropenic by 60Co irradiation or cyclophosphamide treatment retained a limited capacity for mounting a local leukocyte mobilization (LLM) response. Rats irradiated with 700 rad 60Co lacked an LLM. Rats treated with 100 mg/kg cyclophosphamide showed no LLM following an initial low response when assayed originally.

Agranulocytosis↗
PubMed1980

Survival of transitional cell carcinoma cases in 2 Yorkshire centres.

The survival of all cases of bladder cancer presenting in residents of the Huddersfield and Bradford Health Districts has been computed. Cases arising in the 2 districts have been contrasted using a sequential log rank survival method and an excess of deaths in early stage tumours is noted to have occurred in Huddersfield. The reasons for this are discussed.

Adult↗
PubMed1979

Effect of mebendazole on the larval development of three Hymenolepidid cestodes.

Mebendazole or Telmin (which contains 16.7% mebendazole) markedly retarded the development of Hymenolepis diminuta and H. nana when their intermediate hosts Tribolium confusum were fed on flour mixed with it from day 1 to day 10 p.i. Though retardation also occurred with H. microstoma, the effect of the drug on this parasite was noticeably less pronounced than with the other 2 species of this genus.

Animals↗
PubMed1977

Total and "activated" peripheral blood T lymphocytes in patients with thyroid disorders.

The percentage of total and "activated" peripheral blood T lymphocytes was measured in patients with (i) hyperthyroid Graves' disease selected for absence of ophthalmopathy, (ii) treated Graves' disease, with ophthalmopathy, and (iii) other thyroid disorders including subacute thyroiditis, using sheep red blood cell rosette tests. No patient had significantly increased levels of either total or "activated" T lymphocytes. On the other hand, the percentage of total T cells was below normal in 8 of 18 patients with hyperthyroid Graves' disease and in 6 of 18 patients with ophthalmopathy compared with only one of 12 patients with nodular goitres. Similarly, low levels of "activated" T cells were demonstrated in 5 of 18 patients with hyperthyroid Graves' disease and in 10 of 18 patients with ophthalmopathy compared with only one of 12 patients with nodular goitres. Three of four patients with subacute thyroiditis tested had depressed levels of total T lymphocytes whilst only one had low levels of "activated" T lymphocytes. Levels returned to normal during the recovery phase in the two patients with positive tests who were retested. Depressed levels of T lymphocyte populations in patients with Graves' disease and subacute thyroiditis may be due to feedback suppression and/or "exhaustion" in association with the thyroidal and orbital immunological reactions.

Adult↗
PubMed1976

Empathic listening test: an instrument for the selection and training of telephone crisis workers.

Although telephone crisis centers have been shown to be a viable mode of community service, they are not without problems. Empirically based research upon which to make appropriate clinical and administrative decisions, particularly in the selection and training of volunteers has been lacking. In response to that need, a construct was developed that fused listening, the primary communicative behavior, with empathy, the most important interpersonal function of crisis center workers, to provide a criterion for selection and training. A 60-item situational instrument was developed to measure three dimensions of Empathic Listening, (a) Understanding, (b) Interest, and (c) Response-Ability. This study was designed to establish validity and reliability data for the instrument. The instrument was shown to have potential for selecting and training crisis center workers.

Communication↗
PubMed1975

Letter: SI units.

Explore the source record for details and available documents.

Group Practice↗
PubMed1975

Angiotensin- and norepinephrine-induced myocardial lesions: experimental and clinical studies in rabbits and man.

The ability of large doses of exogenous angiotensin II to cause widespread multifocal microscopic myocardial necrosis in the rabbit has been confirmed. Angiotensin II also consistently produced acute renal failure with, less consistently, renal tubular necrosis. Norepinephrine infusions caused histologically indistinguishable myocardial lesions, but did not detectably affect renal function or histology. Severe renal failure, induced by bilateral nephrectomy (with or without concurrent glycerol administration) was not associated with similar cardiac lesions. Acute renal failure of comparable or greater severity to that induced by angiotensin II was produced by intramuscular cephaloridine, and was not associated with cardiac lesions. Rabbits infused with saline intravenously or "sham"-operated by simply opening and closing the peritoneal cavity did not develop renal failure and showed no cardiac or renal lesions histologically. Myocardial lesions, apparently identical to those seen in the rabbits, were observed postmortem in three patients known to have had high circulating levels of angiotensin II before death, although in all three cases alternative explanations are possible. Unexplained arrhythmia, cardiac arrest, and central chest pain without clear cardiographic or serum enzyme evidence of myocardial infarction occurred in two other subjects with very high plasma levels of angiotensin II. These attacks ceased after bilateral nephrectomy and a consequent fall in plasma angiotensin II. The cardiac attacks in these five patients all occurred during or shortly after procedures, such as sodium-depleting dialysis, renal artery surgery, or diazoxide administration, known to cause increase in plasma concentrations of renin and angiotensin II.

Acute Kidney Injury↗