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Biomedical subjects

B Gosselin

Publications and source records attributed to B Gosselin.

At least 217 records · Page 12Linked to original sources
PubMed1975

Enzymes in the cerebrospinal fluid in diagnosis of brain death.

The increase of enzymes in the cerebrospinal fluid is shown to indicate an adverse prognosis, with the implication of irreversibility. The massive increase of glutamate-oxaloacetate transaminase and lactate dehydrogenase and the appearance of alkaline phosphatases in a sample of cerebrospinal fluid in which the cytology is normal constitute an easy and reliable test for brain death. The increase in lactate dehydrogenase fraction V and lysozyme in cerebrospinal fluid supports the macrophagic origin of these enzymes.

Alkaline Phosphatase↗
PubMed1975

[Atrio-ventricular block in Steinert's disease. Electrophysioligic and histologic study of the conduction system].

An anatomical study of the conducting pathways was carried out in a case of Steinert's disease complicated by a complete atrio-ventricular block with syncope. Electrical study of the potentials in the bundle of His located the block within and below the bundle. When the patient died, an anatomical study of the conducting pathways was carried out. There were foci of fibrosis mainly within the conducting system, but these changes were moderately marked only, and seemed to be the final stage of a disorder which was not itself visible optically. The basic underlying pathological process is probably biochemical, and the lesions seen microscopically are simply a late sign of the disorder.

Cardiomyopathies↗
PubMed1974

[Atrio-ventricular block in rheumatoid polyarthritis. Histological study of the His-Tawara system. Apropos of 2 cases].

A histological study of the conduction pathways was performed by serial sections in two patients who died with atrio-ventricular block in the course of rhumatoid arthritis. In the first case, the conduction disturbance was preceded by attacks of supra-ventricular paroxysmal tachycardia. The His-Tawara system was wholly infiltrated by a cast of lympho-plamocytes starting from rhumatoid nodules located at the base of both mitral and tricuspid valves and at the root of the aorta. The sinus node was the seat of a common fibrosis. In the second case, the atrio-ventricular block was secondary to amylosis which predominated in the central fibrous node and in the adjacent small coronary vessels. The His-Tawara system was completely destroyed down to its bifurcation. The sinus node was normal.

Adult↗