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Biomedical subjects

B Gattegno

Publications and source records attributed to B Gattegno.

At least 91 records · Page 5Linked to original sources
PubMed1990

[Treatment of hemorrhagic cystitis caused by cyclophosphamide using intravesical instillation of potassium alum. Apropos of 5 cases].

Five patients with malignant hemopathies, including four treated by bone marrow transplantation, developed cyclophosphamide-induced hemorrhagic cystitis that failed to respond to the usual treatments. Each was treated by continuous irrigation of the bladder with potassium alum. Hematuria ceased in three patients followed up for 5 to 10 months. A review of the literature confirmed the 75% success rate of this treatment. No local side effects were recorded, but one patient had a single seizure.

Administration, Intravesical↗
PubMed1990

[Hautmann enterocystoplasty. Clinical and urodynamic study in 24 patients].

Twenty-four patients with invasive bladder cancer underwent Hautmann enterocystoplasty. A study of the urinary continence revealed 100 per cent of good results during the day and 87.5 per cent of good results at night. Urodynamic investigation after 3 months revealed that only one patient presented with peristaltic waves and that the postmicturating residual urine volume was always less than 100 cc. There was no mortality in this series. The only uncertainty concerns the long-term outcome of these patients because of the risk of incomplete emptying and distension of the neobladder.

Aged↗
PubMed1990

[Report of a case of malignant vesical pheochromocytoma. Diagnosis and therapy].

Bladder pheochromocytoma is a rare, usually benign bladder tumor. An exceptionally malignant bladder pheochromocytoma is reported with more than 5 years follow-up. The study of our case, and the review of 15 other cases reported in the literature show that surgery is the only effective therapy. Partial cystectomy with regional lymphadenectomy, when feasible is the treatment of choice. Because metastatic occurrence may be late, we emphasize the importance of long term follow-up.

Adrenal Gland Neoplasms↗
PubMed1990

[Treatment of urethral stenosis using a pedicled flap of the scrotal skin. Long-term results in 16 patients].

The scrotal skin is vascularized in part by means of the superficial perineal branch of the internal pudendal artery. This nutrient pedicle, together with the scrotal skin dependent on it, can be isolated. The urethra is approached via the perineum. The stricture is incised longitudinally right down to the healthy area. The scrotal flap and pedicle are mobilized, and then anastomosed along the edges of the urethra. From March 1983 through April 1987, sixteen patients have been operated. Postoperative results: the mean follow-up for the 16 patients is 60 months with extremes of 24 and 66 months. 13/16 patients show good results (81%). 3/16 patients show poor results with recurrence of the stricture localized at the junction of the flap and healthy urethra. Such recurrences have yielded to treatment, in two cases, by optical urethrotomy and, in the other case, by means of a new scrotal flap.

Follow-Up Studies↗
PubMed1990

[Low-pressure enterocystoplasty after prostato-cystectomy for cancer. Apropos of 13 cases].

Thirteen patients were operated for bladder carcinoma, from November 1987 to September 1988, using a Camey type II low pressure ileal bladder replacement. Clinical, radiological and urodynamic findings were studied. Diurnal continence was always acquired at three months. In terms of nocturnal continence, only 75 percent of the patients are comfortable, while two patients require oxybutinin to remain continent. Urodynamic exploration showed a low pressure in 8 patients, but a high pressure peak in 4 patients. Radiological study showed integrity of the urinary tract. This work confirmed the improvement obtained with the Camey II procedure. Nevertheless, it also shows the failure of the method with occasional high pressure peaks. We think that a more anatomical bladder reconstruction, such as Hautmann Pouch, may improve the results for nocturnal continence. This needs to be confirmed by a comparative study.

Aged↗
PubMed1989

[Accidental discovery of renal cancer by ultrasonography].

A retrospective study of 152 consecutive patients admitted for renal carcinoma between January, 1969 and August, 1987 showed that these patients could be divided into two groups, the dividing line being 1980, date of the advent of ultrasonography. Compared with the 68 patients treated between 1969 and 1980, the 84 patients treated between 1981 and 1987 had a significantly greater number of asymptomatic renal carcinomas. The asymptomatic tumours discovered incidentally by ultrasounds were less advanced than the symptomatic tumours, the difference between the 2 groups being highly significant. The diagnosis of asymptomatic renal carcinoma at an early stage suggests that these tumours might have a better prognosis. These data underline the usefulness of a systematic study of the kidney during all abdominal or vesicoprostatic ultrasonographic explorations.

Female↗
PubMed1988

A serious complication of vesical ether instillation: ether cystitis.

We report the fourth case of ether cystitis, which occurred after ether was used to dissolve a Foley catheter balloon. The severity of the lesions required an ileocystoplasty to preserve normal micturition. Ether dissolution of Foley catheter balloons should be replaced with mechanical disruption.

Administration, Intravesical↗
PubMed1988

[Extracorporeal lithotripsy and prophylactic antibiotic therapy].

During ESWL, bacteria which may be contained in the stone gets disintegrated. This study evaluates the role of prophylactic antibiotherapy in preventing such complications. Fifty patients whose urine culture was negative were randomized into two groups: the first group (25 patients) received a placebo, the second group received Ceftriaxone 1 g I.V. as a single injection performed 1 hour previous ESWL. There was no positive blood culture and no positive urine culture in the placebo group arm as well as in the antibiotic group. In this study, the risk of infection induced by ESWL seems to be minimal, so that prophylactic antibiotherapy does not appear to be necessary when urine before ESWL is sterile.

Bacterial Infections↗
PubMed1987

[Prophylactic antibiotic therapy in urology].

Prophylactic antibiotic therapy is used increasingly frequently in urology to prevent post-operative septic complications. The use of this method is based on experimental and clinical data which define the optimal time of administration of the antibiotic and the criteria for selection of the most effective drug. Transurethral resection of the prostate is the urological operation most frequently associated with antibiotic prophylaxis. It has been the subject of a large number of randomised studies which have confirmed the efficacy and usefulness of antibiotic prophylaxis. The other urological operations are reviewed and a critical study of the basis for antibiotic prophylaxis for each one is presented.

Anti-Bacterial Agents↗
PubMed1986

Primary nonseminomatous germ cell tumor of the prostate.

We describe a case of a primary nonseminomatous germ cell prostatic tumor and discuss the problem of extragonadal germ cell tumors. Prognosis, staging and management of these tumors are similar to that of metastatic primary testicular germ cell tumors.

Adult↗
PubMed1985

Biological tolerance to polydioxanone absorbable clips: a comparison with metallic ligating clips.

An experiment was conducted in 96 rats to determine the tissue tolerance to a hemostatic and absorbable clip made of polydioxanone, as compared to standard metallic clips. Clinical tolerance was similar and no bleeding or death occurred because of the material. Pathological studies showed a mild histiocytic reaction with absorbable clips and a stronger inflammatory reaction with metallic clips. This experiment indicates that absorbable clips are efficient and well tolerated and we strongly recommend the use of this material.

Absorption↗
PubMed1985

[What is the use of the radioimmunoassay of prostatic acid phosphatase?].

Radioimmunoassay (RIA) of prostatic acid phosphatases (PAP) using the Gammadab (R) PAP pack supplied by Clinical Assays in an effective method for determining extension of prostatic cancer. In patients with lymph node or metastatic invasion serum assay values are almost always elevated (sensitivity = 94%), especially with well differentiated cancer. Elevated levels of this variable are practically pathognomonic of external extension (specificity = 94%). This is of importance in therapy since the degree of invasion determines the choice between palliative and curative treatment. Strategy leading to this therapeutic choice can be greatly simplified and thus modified by RIA of PAP.

Acid Phosphatase↗
PubMed1985

[Inferior vena cava thromboses in renal cancers. 20 years' experience].

The authors present a detailed review of a personal series with careful evaluation of the level of the caval thrombus as far as the right auricle, the degree of lymph node involvement, the surgical treatment and the duration of survival. In contrast with earlier rather optimistic papers, this study revealed a generally poor prognosis. The authors consider that when the cancer has invaded the vena cava, distant microscopic metastases are already present at the time of operation. In the absence of an effective chemotherapy, this type of surgery should only be performed in carefully selected cases (good general health, no signs of metastases or lymph node involvement). In cases with supradiaphragmatic thrombus, cardio-pulmonary by-pass, which is now a common procedure, appears to be safest technique.

Adult↗
PubMed1984

Paraneoplastic hypercalcemia associated with bladder carcinoma: report of 2 cases.

Hypercalcemia associated with bladder carcinoma is rare. We report on 2 patients with hypercalcemia and bladder tumor without bone metastases. In both patients serum calcium returned to normal after removal of the tumor. Serum immunoreactive parathyroid hormone levels were normal in both patients. In 1 case a high gradient of immunoreactive parathyroid hormone across the tumor was demonstrated but the secretion of nephrogenous cyclic adenosine monophosphate was normal. Urinary excretion of prostaglandins also was normal in this case. These data show that hypercalcemia was caused by the tumoral production of some humoral factor different from parathyroid hormone.

Adult↗