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Biomedical subjects

B Gasior-Chrzan

Publications and source records attributed to B Gasior-Chrzan.

24 records · Page 2Linked to original sources
PubMedDate not supplied

[Effect of ovalbumin lysozyme on healing of standard skin wounds in guinea pigs].

External application of ovalbumin Lysozyme in normal saline in enzyme concentration 1 mg/ml shortened evidently the time of healing of standard skin wounds in guinea pigs (p less than 0.00001) as compared to control groups. The inflammatory reaction around the wound was reduced also. No manifestations of allergy to ovalbumin lysozyme were noted. This favourable effect of lysozyme on wound healing seems to be related to the cationic influence of lysozyme on cell membranes of keratinocytes and on change of wound pH.

Administration, Cutaneous↗
PubMedDate not supplied

Serum alpha 2-macroglobulin levels in psoriatic patients treated with UVB and PUVA.

BACKGROUND: Abnormalities in proteinase metabolisms have been found in psoriasis and higher concentrations of neutral proteinases in psoriatic skin lesions than in unaffected skin of psoriatic patients have been observed. AIM: The aim of the study was to determine whether repeated whole body UV-(UVB and PUVA) irradiation is associated with changes in proteinase inhibitor alpha 2-macroglobulin (alpha 2-M) in patients with active plaque psoriasis. PATIENTS AND METHODS: In this study, the sera alpha 2-M levels were evaluated in cases of active plaque psoriasis before UV-, four weeks UVB (15 patients) and PUVA (11 patients) irradiation, and two weeks after completed treatment. RESULTS: Both UVB and PUVA treatment had no significant influence on alpha 2-M levels in psoriatic sera, it was, however, sufficient to treat most of the skin lesions. DISCUSSION: The beneficial effect of phototherapy in psoriasis seems not to be mediated through increased binding of proteinases by proteinases inhibitor alpha 2-M from serum.

Adult↗