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Biomedical subjects

B Franc

Publications and source records attributed to B Franc.

At least 91 records · Page 5Linked to original sources

Time course of night sleep EEG in the first year of life: a description based on automatic analysis.

The aim of this study is to describe the time course of night sleep in the first year of life. Forty-eight infants aged between 1 and 54 weeks were polygraphically recorded for 1 night. The central occipital EEG derivation was processed with a lab computer in order to obtain every 30 sec an EEG parameter value. The parameter is based on the joint frequency-amplitude distribution of the EEG and displays fluctuations between 2 extreme levels, high voltage low frequency (HVLF) and low voltage high frequency (LVHF). The range of the fluctuations between HVLF and LVHF increases from the period of 1-6 weeks to the period of 7-14 weeks. A further increase of the parameter range occurs after 24 weeks, which remains restricted to the first half of the night. The recurrence time of LVHF and HVLF episodes (possibly corresponding to quiet sleep paradoxical sleep cycles) is about 56 min and does not change with age in the first year of life.

Brain↗

[Medullary cancer of the thyroid: morphological and immunohistochemical definitions. The pathologist's role in 1987].

The morphological and secretories aspects of medullary thyroid carcinomas are reviewed. Mixed follicular and medullary carcinomas are discussed. Criteria for discrimination between sporadic and hereditary forms are mentioned with special reference on C cell hyperplasia. After a brief report on what is known about normal human and animal C cell, a short histogenetic discussion is debated.

Calcitonin↗

[Extramembranous glomerulopathy in chronic B lymphoid leukemia. 5 years' follow-up].

A nephrotic syndrome due to membranous nephropathy and B chronic lymphocytic leukemia were simultaneously discovered in a 52 year old patient. Proteinuria was significantly reduced with chlorambucil therapy and nephrotic syndrome disappeared. Treatment withdrawal for 5 months resulted in a significant lowering of serum albumin level, while blood lymphocyte count increased. These observations indicate a probable causal relationship between the lymphoproliferative disease and the onset of the glomerulopathy which is supported by the efficacy of the chemotherapy on the evolution of the nephrotic syndrome.

B-Lymphocytes↗

[Syndrome of alveolar hemorrhage associated with systemic cholesterol embolism].

Vascular purpura and haemoptysis developed in a patient suffering from accelerated hypertension and rapidly progressive renal failure due to cholesterol embolism. Alveolar haemorrhage was diagnosed on the association of clinical and endoscopic results, and on the outcome of the disease. This syndrome is usually associated with other immunological disorders and raises the question of immunological phenomena being the cause of some of the clinical manifestations observed after cholesterol embolism.

Acute Kidney Injury↗

[A systemic-like disease: chronic vitamin A poisoning].

A 22-year-old man, had ingested more than 300 10(6) I.U. of vitamin A over a 2-year period. He presented with diffuse arthralgia, weight loss, low-grade fever, dryness and peeling of the skin, hair loss, liver enlargement with ascites and pleural effusion. He had a raised E.S.R., hypercalcemia and acute renal failure. Plasma levels of vitamin A and retinol-binding-protein were in the normal range. All symptoms disappeared after withdrawal of vitamin A except for the liver enlargement. Iliac bone biopsy showed cortical thickening, numerous resorptive lacunae and no index of bone formation. Liver biopsy showed obliteration of the space of Disse by swollen fat-storing cells (Ito cells). Tissue levels of vitamin A were very high in the liver. A second biopsy, 6 months later, showed a decrease of fat storage in the Ito cells but the development of a fibrosis.

Adult↗

[Vascular malformations of the digestive tract: a cause of severe digestive hemorrhage. Apropos of 2 cases].

We report on two cases of angiodysplasia of the digestive tract complicated by serious acute bleeding. The preoperative diagnoses were made by angiography. One case concerned a voluminous jejunal lesion which was macroscopically visible; the other concerned a punctiform lesion detected only by angiography and not found on the pathology specimen. The authors insist on the potential gravity of these angiodysplastic lesions, the necessity to perform an emergency celio-mesenteric angiogram when confronted with a serious digestive tract hemorrhage non-explained by conventional methods of exploration when they can be performed.

Adult↗

Data entry on a computer terminal: repetitive work strains on the oculomotor and central nervous systems.

Continuous telemetric recordings including E.K.G., E.O.G., and E.E.G. were carried out on two subjects during 4 working days: 1 day of "reference work" or classical clerical activities, 3 days of "data entry work". Although the time allowed for the task was not limited, the performance assessed from oculomotor patterns remained stable throughout the day, from one day to the next and from one subject to another. This stability was reflected on the stereotyped E.E.G. patterns recorded during the work period, the differences occurring between reading and typing were more acute in the left cortical hemisphere than in the right. As a result of these stable patterns, the ultradian oscillations of the behavioural and physiological parameters were less during data entry than during work reference. The only possible time adjustments were the interruptions or breaks between two document pages and their variations could be considered as indicators of work load.

Adult↗

[Angioma of the thyroid gland. Apropos of a case].

The discovery of one angioma of the thyroid among 1000 thyroidectomy specimens examined confirmed the extremely rare nature of this lesion. These angiomas, localized to the thyroid gland, are observed in adults and could result from an intrathyroidal mesenchymatous inclusion. They should be distinguished from childhood forms which occur within the framework of an almost always fatal multiple viscera angiomatous disease. Diagnosis is difficult before operation, while the prognosis is excellent after partial thyroid excision.

Female↗