Search PubMed⌕ Search

Biomedical subjects

B Flannigan

Publications and source records attributed to B Flannigan.

11 recordsLinked to original sources
PubMed1992

Injuries of the superior portion of the glenoid labrum involving the insertion of the biceps tendon: MR imaging findings in nine cases.

The goal of this investigation was to describe the MR appearance of traumatic fraying or detachment of the superior portion of the glenoid labrum including the insertion of the tendon of the long head of the biceps. This condition is caused either by an acute injury or by repeated overhead motion during participation in sports. In nine patients with such a lesion, the arthroscopic report and MR images were available for review. These patients were 22-64 years old (mean, 38). In four patients only fraying was noted during arthroscopy, in four patients the superior part of the labrum was detached together with the insertion of the biceps tendon, and in one case there was a bucket-handle tear of the superior portion of the labrum. The MR images were retrospectively evaluated by three osteoradiologists in conference. Signal changes within the labrum and detachment of the labrum were noted, and the findings were compared with the results of arthroscopy. MR imaging did not allow recognition of simple fraying. In two of the five cases with arthroscopic findings of detachment of the superior labrum from the glenoid rim, differentiation between complete and partial labral detachments was not possible even with MR arthrography. However, in these cases the patient's age and history led to the correct diagnosis. We conclude that early traumatic abnormalities of the superior portion of the labrum cannot be detected with MR imaging. Complete detachment, however, can be demonstrated if the patient's age and history are taken into consideration.

Adult↗
PubMed1990

Quantification of airborne moulds in the homes of children with and without wheeze.

A population survey of 1000 7 year old children found a significant excess of wheeze among children whose homes were reported to be mouldy (odds ratio 3.70, 95% confidence limits 2.22, 6.15). The airborne mould flora was quantified by repeated volumetric sampling during the winter in three rooms of the homes of 88 children. All of these had previously completed spirometric tests before and after a six minute free running exercise challenge. Total airborne mould counts varied from 0 to 41,000 colony forming units (CFU)/m3, but were generally in the range 50-1500 CFU/m3, much lower than the concentrations found outdoors in summer. The principal types of fungi identified are all known to be common out of doors, and most were found on at least one occasion in most of the homes. Median and geometric mean total mould counts were not related to reports of visible mould in the home, or to a history of wheeze in the index child. The heterogeneous group of non-sporing fungi (mycelia sterilia) were the only airborne fungi present at significantly higher concentrations in the homes of wheezy children (geometric mean 2.1 v 0.7 CFU/m3. A non-significant increase in total mould counts was observed in the homes of children with a 10% or greater decline in FEV1 after exercise (geometric mean 354 v 253 CFU/m3). Questionnaire reports of mould in the home may be a poor indicator of exposure to airborne spores. The total burden of inhaled mould spores from indoor sources is probably not an important determinant of wheeze among children in the general population. Although the association with mycelia sterilia could be a chance finding, these non-sporing isolates may include a potent source of allergen.

Bronchi↗
PubMed1990

MR arthrography of the shoulder: comparison with conventional MR imaging.

Twenty-three patients underwent both conventional MR imaging of the shoulder and MR shoulder arthrography for clinically suspected labral or rotator cuff abnormalities. Images obtained before and after contrast administration were studied independently, and without knowledge of clinical findings, by two radiologists for the presence of abnormalities of the glenoid labrum or rotator cuff. Results were correlated with surgical findings in all patients. Nine patients had surgically proved labral tears. MR arthrography detected all nine labral abnormalities, while six of the nine were missed on conventional MR imaging. Fourteen patients had surgically proved rotator cuff tears. MR arthrography detected 11 of the 14 tears and missed three partial tears on the bursal surface. Conventional MR imaging detected nine cuff tears and missed five tears; two of these were complete rotator cuff tears and three were partial tears of the undersurface of the rotator cuff. Our results suggest that MR arthrography enhances the accuracy of MR in the evaluation of the glenoid labrum and rotator cuff tendon.

Adolescent↗
PubMed1988

Morphological studies on clinical isolates of Aspergillus fumigatus.

Morphological variation was examined in 19 strains of Aspergillus fumigatus Fres. isolated from the sputum of five patients with aspergilloma. For each patient a series of variant strains was obtained which exhibited gross differences in growth rate, colour and texture of the colony. On microscopical examination, some of the strains were found to produce markedly abnormal fruiting heads which were uncharacteristic for the species. Scanning electron microscopy revealed that the variant produced conidia of anomalous size, shape and surface-sculpturing. The significance of the isolation of morphological variants of A. fumigatus in sputum and their selection in vivo are discussed.

Aspergillosis↗
PubMed1988

The use of MRI to assist in diagnosis of pigmented villonodular synovitis of the knee joint.

Pigmented villonodular synovitis (PVNS) of the knee joint remains a difficult and elusive entity to define and characterize. This entity most often appears in the young adult knee with nonspecific clinical features, including a painful range of motion and perhaps a sensation of locking. Detection and diagnosis of this localized soft-tissue mass are difficult because plain roentgenograms may be totally within normal limits. The case of a 21-year-old woman illustrates the use of magnetic resonance imaging (MRI) as an effective technique to define and characterize PVNS. Advantages of MRI include high-resolution/high-contrast multiplanar sections that depict bone, marrow, ligaments and tendons, fat, menisci, and articular cartilage in one image. In addition, MRI is noninvasive and requires no ionized radiation. MRI is an excellent clinical tool for the evaluation of intraarticular tumors of the knee joint.

Adult↗
PubMed1987

Magnetic resonance imaging in the diagnosis of disc degeneration: correlation with discography.

One hundred and one disc levels in 36 patients with low-back pain were studied with magnetic resonance imaging (MRI) (T2-weighted) sagittal images and conventional roentgenographic discography to detect early disc degeneration. Thirty-nine discs also were evaluated after discography with roentgenographic CT MRI findings were compared with discography results. MRI was 99% accurate in predicting normality or abnormality as determined by discography. Changes in disc signal on MRI accurately reflected the presence or absence of degenerative changes seen on discography in patients with low-back pain. Clinically, MRI is a useful technique for detecting early disc degeneration and for assessing the affected disc level and adjacent levels in patients with low-back pain and spondylolithesis.

Adolescent↗
PubMed1987

MR imaging of the intratemporal facial nerve by using surface coils.

MR images of the intratemporal portion of the facial nerve were obtained with surface coils using a 0.3-T permanent magnet whole-body imaging system. Various 2DFT spin-echo pulse sequences were used to produce 5-mm thick sections with 0.5-mm pixels on a 512 X 512 acquisition matrix. The MR images from normal volunteers were correlated with cryosection specimens of three fresh human cadavers. The seventh nerve was followed in the internal auditory and fallopian canal and through temporal bone to the stylomastoid foramen. The entire labyrinthine, tympanic, and mastoid portions, as well as the geniculate ganglion, could be shown with appropriate scan planes. MR produces excellent images of the facial nerve with high-contrast resolution. Unlike CT, no beam-hardening artifact from the temporal bone is apparent. MR should be a sensitive study for the evaluation of intratemporal facial nerve disease.

Facial Nerve↗
PubMed1986

Multiple-angle, variable-interval, nonorthogonal MRI.

Multiple-angle, variable-interval, nonorthogonal (MAVIN) MRI is a new, time-saving technique that allows for the independent choice of slice angle and position for each slice in a multiangle pulse sequence. By appropriate adjustment of the slice-select radiofrequency pulse and the slice-select and readout magnetic-field gradients, the interval and angle of each slice may be individually chosen. MAVIN can reduce examination time in studies of the lumbar spine, orbits, knees, and heart, where nonparallel oblique scanning may be necessary and would otherwise require the use of additional pulse sequences. Loss of signal in the region of intersection of multiple planes due to local changes in effective repetition time is a practical limitation. For this reason, scan planes are chosen so that the intersection does not overlie the region of interest.

Humans↗
PubMed1986

Dynamic-range compression in surface-coil MRI.

The large dynamic range in signal intensity present in MR surface-coil images makes proper windowing and photography difficult. By removing the low-spatial frequency information caused by variations in surface-coil field intensity from the high-spatial frequency information containing the image data, a considerable compression of this dynamic range of signal intensity is possible. To accomplish this, a technique was implemented on a digital computer for use with MR surface-coil image data. The compression was done as a postprocessing option after the patient scan had been completed and therefore did not alter actual scan times. Although the image signal-to-noise was not altered, the ease of photography for most images was improved. Thus, digital dynamic-range compression is a practical technique to aid in surface-coil MRI studies.

Adenocarcinoma↗